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Erschienen in: Archives of Women's Mental Health 6/2014

01.12.2014 | Original Article

Decisional conflict among women considering antidepressant medication use in pregnancy

verfasst von: Georgia D. Walton, Lori E. Ross, Donna E. Stewart, Sophie Grigoriadis, Cindy-Lee Dennis, Simone Vigod

Erschienen in: Archives of Women's Mental Health | Ausgabe 6/2014

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Abstract

The purpose of this study was to examine decision-making among women considering antidepressant medication use in pregnancy. Decisional conflict was assessed using the Decisional Conflict Scale (DCS) among pregnant women considering antidepressant medication treatment (N = 40). Overall DCS and subscale scores were compared between women who were antidepressant users and non-users. Semi-structured interviews (N = 10) explored barriers and facilitators of decision-making. Twenty-one women (52 %) had moderate or high decisional conflict (DCS ≥ 25). Overall DCS scores did not differ between groups, but antidepressant use was associated with feeling more adequately informed (subscale mean 17.5, SD 17.9 vs. 42.1, SD 23.8, p = 0.001) and clear about values (subscale mean 16.7, SD 15.1 vs. 29.8, SD 24.0, p = 0.043). Barriers to decision-making were (1) difficulty weighing maternal versus infant health, (2) lack of high quality information, (3) negative external influences, and (4) emotional reactions to decision-making. Facilitators were (1) interpersonal supports, (2) accessible subspecialty care, and (3) severe depressive symptoms. Many pregnant women facing decisions regarding antidepressant medication use experience decisional conflict. Interventions that provide accurate information, assistance with weighing risks and benefits of treatment, management of problematic external influences, and emotional support may reduce decisional conflict and facilitate the decision-making process.
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Literatur
Zurück zum Zitat Battle CL, Salisbury AL, Schofield CA, Ortiz-Hernandez S (2013) Perinatal antidepressant use: understanding women’s preferences and concerns. J Psychiatr Pract 19(6):443–453PubMedCrossRef Battle CL, Salisbury AL, Schofield CA, Ortiz-Hernandez S (2013) Perinatal antidepressant use: understanding women’s preferences and concerns. J Psychiatr Pract 19(6):443–453PubMedCrossRef
Zurück zum Zitat Beck CT (1998) The effects of postpartum depression on child development: a meta-analysis. Arch Psychiatr Nurs 12(1):12–20PubMedCrossRef Beck CT (1998) The effects of postpartum depression on child development: a meta-analysis. Arch Psychiatr Nurs 12(1):12–20PubMedCrossRef
Zurück zum Zitat Bonari L, Koren G, Einarson TR, Jasper JD, Taddio A, Einarson A (2005) Use of antidepressants by pregnant women: evaluation of perception of risk, efficacy of evidence based counseling and determinants of decision making. Arch Womens Ment Health 8(4):214–220PubMedCrossRef Bonari L, Koren G, Einarson TR, Jasper JD, Taddio A, Einarson A (2005) Use of antidepressants by pregnant women: evaluation of perception of risk, efficacy of evidence based counseling and determinants of decision making. Arch Womens Ment Health 8(4):214–220PubMedCrossRef
Zurück zum Zitat Braun V, Clarke V (2006) Using thematic analysis in psychology. Qual Res Psychol 3:77–101CrossRef Braun V, Clarke V (2006) Using thematic analysis in psychology. Qual Res Psychol 3:77–101CrossRef
Zurück zum Zitat Chambers CD, Hernandez-Diaz S, Van Marter LJ, Werler MM, Louik C, Jones KL, Mitchell AA (2006) Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N Engl J Med 354(6):579–587PubMedCrossRef Chambers CD, Hernandez-Diaz S, Van Marter LJ, Werler MM, Louik C, Jones KL, Mitchell AA (2006) Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N Engl J Med 354(6):579–587PubMedCrossRef
Zurück zum Zitat Gavin NI, Gaynes BN, Lohr KN, Meltzer-Brody S, Gartlehner G, Swinson T (2005) Perinatal depression: a systematic review of prevalence and incidence. Obstet Gynecol 106(5 Pt 1):1071–1083PubMedCrossRef Gavin NI, Gaynes BN, Lohr KN, Meltzer-Brody S, Gartlehner G, Swinson T (2005) Perinatal depression: a systematic review of prevalence and incidence. Obstet Gynecol 106(5 Pt 1):1071–1083PubMedCrossRef
Zurück zum Zitat Gibson J, McKenzie-McHarg K, Shakespeare J, Price J, Gray R (2009) A systematic review of studies validating the Edinburgh Postnatal Depression Scale in antepartum and postpartum women. Acta Psychiatr Scand 119(5):350–364PubMedCrossRef Gibson J, McKenzie-McHarg K, Shakespeare J, Price J, Gray R (2009) A systematic review of studies validating the Edinburgh Postnatal Depression Scale in antepartum and postpartum women. Acta Psychiatr Scand 119(5):350–364PubMedCrossRef
Zurück zum Zitat Grigoriadis S, VonderPorten EH, Mamisashvili L, Eady A, Tomlinson G, Dennis CL, Ross LE (2013a) The effect of prenatal antidepressant exposure on neonatal adaptation: a systematic review and meta-analysis. J Clin Psychiatry 74(4):e309–e320PubMedCrossRef Grigoriadis S, VonderPorten EH, Mamisashvili L, Eady A, Tomlinson G, Dennis CL, Ross LE (2013a) The effect of prenatal antidepressant exposure on neonatal adaptation: a systematic review and meta-analysis. J Clin Psychiatry 74(4):e309–e320PubMedCrossRef
Zurück zum Zitat Grigoriadis S, VonderPorten EH, Mamisashvili L, Roerecke M, Rehm J, Dennis CL, Ross LE (2013b) Antidepressant exposure during pregnancy and congenital malformations: is there an association? A systematic review and meta-analysis of the best evidence. J Clin Psychiatry 74(4):e293–e308PubMedCrossRef Grigoriadis S, VonderPorten EH, Mamisashvili L, Roerecke M, Rehm J, Dennis CL, Ross LE (2013b) Antidepressant exposure during pregnancy and congenital malformations: is there an association? A systematic review and meta-analysis of the best evidence. J Clin Psychiatry 74(4):e293–e308PubMedCrossRef
Zurück zum Zitat Grigoriadis S, VonderPorten EH, Mamisashvili L, Tomlinson G, Dennis CL, Koren G, Ross LE (2013c) The impact of maternal depression during pregnancy on perinatal outcomes: a systematic review and meta-analysis. J Clin Psychiatry 74(4):e321–e341PubMedCrossRef Grigoriadis S, VonderPorten EH, Mamisashvili L, Tomlinson G, Dennis CL, Koren G, Ross LE (2013c) The impact of maternal depression during pregnancy on perinatal outcomes: a systematic review and meta-analysis. J Clin Psychiatry 74(4):e321–e341PubMedCrossRef
Zurück zum Zitat Guest G, Bunce A, Johnson L (2006) How many interviews are enough? An experiment with data saturation and variability. Field Methods 18(1):59–82CrossRef Guest G, Bunce A, Johnson L (2006) How many interviews are enough? An experiment with data saturation and variability. Field Methods 18(1):59–82CrossRef
Zurück zum Zitat Hammen C, Brennan PA (2003) Severity, chronicity, and timing of maternal depression and risk for adolescent offspring diagnoses in a community sample. Arch Gen Psychiatry 60(3):253–258PubMedCrossRef Hammen C, Brennan PA (2003) Severity, chronicity, and timing of maternal depression and risk for adolescent offspring diagnoses in a community sample. Arch Gen Psychiatry 60(3):253–258PubMedCrossRef
Zurück zum Zitat Janis I (1977) Decision making. The Free Press, New York Janis I (1977) Decision making. The Free Press, New York
Zurück zum Zitat Kennedy SH, Lam RW, Parikh SV, Patten SB, Ravindran AV (2009) Canadian Network for Mood and Anxiety Treatments (CANMAT) clinical guidelines for the management of major depressive disorder in adults. Introduction. J Affect Disord 117(Suppl 1):S1–S2PubMedCrossRef Kennedy SH, Lam RW, Parikh SV, Patten SB, Ravindran AV (2009) Canadian Network for Mood and Anxiety Treatments (CANMAT) clinical guidelines for the management of major depressive disorder in adults. Introduction. J Affect Disord 117(Suppl 1):S1–S2PubMedCrossRef
Zurück zum Zitat Marcus SM, Flynn HA (2008) Depression, antidepressant medication, and functioning outcomes among pregnant women. Int J Gynaecol Obstet 100(3):248–251PubMedCrossRef Marcus SM, Flynn HA (2008) Depression, antidepressant medication, and functioning outcomes among pregnant women. Int J Gynaecol Obstet 100(3):248–251PubMedCrossRef
Zurück zum Zitat Martins C, Gaffan EA (2000) Effects of early maternal depression on patterns of infant-mother attachment: a meta-analytic investigation. J Child Psychol Psychiatry 41(6):737–746PubMedCrossRef Martins C, Gaffan EA (2000) Effects of early maternal depression on patterns of infant-mother attachment: a meta-analytic investigation. J Child Psychol Psychiatry 41(6):737–746PubMedCrossRef
Zurück zum Zitat Murray L (1992) The impact of postnatal depression on infant development. J Child Psychol Psychiatry 33(3):543–561PubMedCrossRef Murray L (1992) The impact of postnatal depression on infant development. J Child Psychol Psychiatry 33(3):543–561PubMedCrossRef
Zurück zum Zitat Nulman I, Rovet J, Stewart DE, Wolpin J, Pace-Asciak P, Shuhaiber S, Koren G (2002) Child development following exposure to tricyclic antidepressants or fluoxetine throughout fetal life: a prospective, controlled study. Am J Psychiatry 159(11):1889–1895PubMedCrossRef Nulman I, Rovet J, Stewart DE, Wolpin J, Pace-Asciak P, Shuhaiber S, Koren G (2002) Child development following exposure to tricyclic antidepressants or fluoxetine throughout fetal life: a prospective, controlled study. Am J Psychiatry 159(11):1889–1895PubMedCrossRef
Zurück zum Zitat O’Connor AM (1995) Validation of a decisional conflict scale. Med Decis Making 15(1):25–30PubMedCrossRef O’Connor AM (1995) Validation of a decisional conflict scale. Med Decis Making 15(1):25–30PubMedCrossRef
Zurück zum Zitat O’Connor A (1997) Decisional conflict. In: McFarland G, McFarlane E (eds) Nursing diagnosis and intervention, 3rd edn. The CV Mosby Co., St. Louis, pp 486–496 O’Connor A (1997) Decisional conflict. In: McFarland G, McFarlane E (eds) Nursing diagnosis and intervention, 3rd edn. The CV Mosby Co., St. Louis, pp 486–496
Zurück zum Zitat O’Connor A, Jacobsen M (2007) Decisional Conflict: supporting people experiencing uncertainty about options affecting their health. Ottawa Health Decision Centre, Ottawa O’Connor A, Jacobsen M (2007) Decisional Conflict: supporting people experiencing uncertainty about options affecting their health. Ottawa Health Decision Centre, Ottawa
Zurück zum Zitat O’Hara MW, Swain AM (1996) Rates and risk of postpartum depression—a meta-analysis. Int Rev Psychiatry 8(1):37–54CrossRef O’Hara MW, Swain AM (1996) Rates and risk of postpartum depression—a meta-analysis. Int Rev Psychiatry 8(1):37–54CrossRef
Zurück zum Zitat Orr ST, Miller CA (1995) Maternal depressive symptoms and the risk of poor pregnancy outcome. Review of the literature and preliminary findings. Epidemiol Rev 17(1):165–171PubMed Orr ST, Miller CA (1995) Maternal depressive symptoms and the risk of poor pregnancy outcome. Review of the literature and preliminary findings. Epidemiol Rev 17(1):165–171PubMed
Zurück zum Zitat Ross LE, Grigoriadis S, Mamisashvili L, Vonderporten EH, Roerecke M, Rehm J, Cheung A (2013) Selected pregnancy and delivery outcomes after exposure to antidepressant medication: a systematic review and meta-analysis. JAMA Psychiatry 70(4):436–443PubMedCrossRef Ross LE, Grigoriadis S, Mamisashvili L, Vonderporten EH, Roerecke M, Rehm J, Cheung A (2013) Selected pregnancy and delivery outcomes after exposure to antidepressant medication: a systematic review and meta-analysis. JAMA Psychiatry 70(4):436–443PubMedCrossRef
Zurück zum Zitat Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, Fava M (2006) Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry 163(11):1905–1917PubMedCrossRef Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, Fava M (2006) Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry 163(11):1905–1917PubMedCrossRef
Zurück zum Zitat Sinclair D, Murray L (1998) Effects of postnatal depression on children’s adjustment to school. Teacher’s reports. Br J Psychiatry 172:58–63PubMedCrossRef Sinclair D, Murray L (1998) Effects of postnatal depression on children’s adjustment to school. Teacher’s reports. Br J Psychiatry 172:58–63PubMedCrossRef
Zurück zum Zitat Sjöberg L (1983) To smoke or not to smoke: conflict or lack of differentiation? In: Humphreys P, Sevenson O, Vari A (eds) Analysing and aiding decision processes. Elsevier, New York Sjöberg L (1983) To smoke or not to smoke: conflict or lack of differentiation? In: Humphreys P, Sevenson O, Vari A (eds) Analysing and aiding decision processes. Elsevier, New York
Zurück zum Zitat Stacey D, Bennett CL, Barry MJ, Col NF, Eden KB, Holmes-Rovner M, Thomson R (2011) Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev(10), CD001431 Stacey D, Bennett CL, Barry MJ, Col NF, Eden KB, Holmes-Rovner M, Thomson R (2011) Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev(10), CD001431
Zurück zum Zitat Steer RA, Scholl TO, Hediger ML, Fischer RL (1992) Self-reported depression and negative pregnancy outcomes. J Clin Epidemiol 45(10):1093–1099PubMedCrossRef Steer RA, Scholl TO, Hediger ML, Fischer RL (1992) Self-reported depression and negative pregnancy outcomes. J Clin Epidemiol 45(10):1093–1099PubMedCrossRef
Zurück zum Zitat Vlemmix F, Warendorf JK, Rosman AN, Kok M, Mol BW, Morris JM, Nassar N (2013) Decision aids to improve informed decision-making in pregnancy care: a systematic review. BJOG 120(3):257–266PubMedCrossRef Vlemmix F, Warendorf JK, Rosman AN, Kok M, Mol BW, Morris JM, Nassar N (2013) Decision aids to improve informed decision-making in pregnancy care: a systematic review. BJOG 120(3):257–266PubMedCrossRef
Zurück zum Zitat Volk R, Llewellyn-Thomas H (2012) The 2012 IPDAS Background Document: bibAn Introduction. In: Volk R, Llewellyn-Thomas H (Eds.), 2012 Update of the International Patient Decision Aid Standards (IPDAS) Collaboration’s Background Document. http://www.ipdas.ohri.ca/resources.html. Accessed 4 April 2014 Volk R, Llewellyn-Thomas H (2012) The 2012 IPDAS Background Document: bibAn Introduction. In: Volk R, Llewellyn-Thomas H (Eds.), 2012 Update of the International Patient Decision Aid Standards (IPDAS) Collaboration’s Background Document. http://​www.​ipdas.​ohri.​ca/​resources.​html. Accessed 4 April 2014
Zurück zum Zitat Weinberg MK, Tronick EZ (1998) The impact of maternal psychiatric illness on infant development. J Clin Psychiatry 59(Suppl 2):53–61PubMed Weinberg MK, Tronick EZ (1998) The impact of maternal psychiatric illness on infant development. J Clin Psychiatry 59(Suppl 2):53–61PubMed
Zurück zum Zitat Wen SW, Yang Q, Garner P, Fraser W, Olatunbosun O, Nimrod C, Walker M (2006) Selective serotonin reuptake inhibitors and adverse pregnancy outcomes. Am J Obstet Gynecol 194(4):961–966PubMedCrossRef Wen SW, Yang Q, Garner P, Fraser W, Olatunbosun O, Nimrod C, Walker M (2006) Selective serotonin reuptake inhibitors and adverse pregnancy outcomes. Am J Obstet Gynecol 194(4):961–966PubMedCrossRef
Zurück zum Zitat Wills CE, Holmes-Rovner M (2003) Preliminary validation of the satisfaction with decision scale with depressed primary care patients. Health Expect 6(2):149–159PubMedCrossRef Wills CE, Holmes-Rovner M (2003) Preliminary validation of the satisfaction with decision scale with depressed primary care patients. Health Expect 6(2):149–159PubMedCrossRef
Zurück zum Zitat Zuckerman B, Amaro H, Bauchner H, Cabral H (1989) Depressive symptoms during pregnancy: relationship to poor health behaviors. Am J Obstet Gynecol 160(5 Pt 1):1107–1111PubMedCrossRef Zuckerman B, Amaro H, Bauchner H, Cabral H (1989) Depressive symptoms during pregnancy: relationship to poor health behaviors. Am J Obstet Gynecol 160(5 Pt 1):1107–1111PubMedCrossRef
Zurück zum Zitat Zuckerman B, Bauchner H, Parker S, Cabral H (1990) Maternal depressive symptoms during pregnancy, and newborn irritability. J Dev Behav Pediatr 11(4):190–194PubMedCrossRef Zuckerman B, Bauchner H, Parker S, Cabral H (1990) Maternal depressive symptoms during pregnancy, and newborn irritability. J Dev Behav Pediatr 11(4):190–194PubMedCrossRef
Metadaten
Titel
Decisional conflict among women considering antidepressant medication use in pregnancy
verfasst von
Georgia D. Walton
Lori E. Ross
Donna E. Stewart
Sophie Grigoriadis
Cindy-Lee Dennis
Simone Vigod
Publikationsdatum
01.12.2014
Verlag
Springer Vienna
Erschienen in
Archives of Women's Mental Health / Ausgabe 6/2014
Print ISSN: 1434-1816
Elektronische ISSN: 1435-1102
DOI
https://doi.org/10.1007/s00737-014-0448-1

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