Deep learning reconstruction for improving image quality of pediatric abdomen MRI using a 3D T1 fast spoiled gradient echo acquisition
- 18.07.2025
- Research
Erschienen in:
- Verfasst von
- Evan J. Zucker
- Eugene Milshteyn
- Fedel A. Machado-Rivas
- Leo L. Tsai
- Nathan T. Roberts
- Arnaud Guidon
- Michael S. Gee
- Teresa Victoria
- Erschienen in
- Pediatric Radiology | Ausgabe 10/2025
Abstract
Background
Deep learning (DL) reconstructions have shown utility for improving image quality of abdominal MRI in adult patients, but a paucity of literature exists in children.
Objective
To compare image quality between three-dimensional fast spoiled gradient echo (SPGR) abdominal MRI acquisitions reconstructed conventionally and using a prototype method based on a commercial DL algorithm in a pediatric cohort.
Materials and methods
Pediatric patients (age < 18 years) who underwent abdominal MRI from 10/2023–3/2024 including gadolinium-enhanced accelerated 3D SPGR 2-point Dixon acquisitions (LAVA-Flex, GE HealthCare) were identified. Images were retrospectively generated using a prototype reconstruction method leveraging a commercial deep learning algorithm (AIR™ Recon DL, GE HealthCare) with the 75% noise reduction setting. For each case/reconstruction, three radiologists independently scored DL and non-DL image quality (overall and of selected structures) on a 5-point Likert scale (1-nondiagnostic, 5-excellent) and indicated reconstruction preference. The signal-to-noise ratio (SNR) and mean number of edges (inverse correlate of image sharpness) were also quantified. Image quality metrics and preferences were compared using Wilcoxon signed-rank, Fisher exact, and paired t-tests. Interobserver agreement was evaluated with the Kendall rank correlation coefficient (W).
Results
The final cohort consisted of 38 patients with mean ± standard deviation age of 8.6 ± 5.7 years, 23 males. Mean image quality scores for evaluated structures ranged from 3.8 ± 1.1 to 4.6 ± 0.6 in the DL group, compared to 3.1 ± 1.1 to 3.9 ± 0.6 in the non-DL group (all P < 0.001). All radiologists preferred DL in most cases (32–37/38, P < 0.001). There were a 2.3-fold increase in SNR and a 3.9% reduction in the mean number of edges in DL compared to non-DL images (both P < 0.001). In all scored anatomic structures except the spine and non-DL adrenals, interobserver agreement was moderate to substantial (W = 0.41–0.74, all P < 0.01).
Conclusion
In a broad spectrum of pediatric patients undergoing contrast-enhanced Dixon abdominal MRI acquisitions, the prototype deep learning reconstruction is generally preferred to conventional methods with improved image quality across a wide range of structures.
Graphical Abstract
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- Titel
- Deep learning reconstruction for improving image quality of pediatric abdomen MRI using a 3D T1 fast spoiled gradient echo acquisition
- Verfasst von
-
Evan J. Zucker
Eugene Milshteyn
Fedel A. Machado-Rivas
Leo L. Tsai
Nathan T. Roberts
Arnaud Guidon
Michael S. Gee
Teresa Victoria
- Publikationsdatum
- 18.07.2025
- Verlag
- Springer Berlin Heidelberg
- Erschienen in
-
Pediatric Radiology / Ausgabe 10/2025
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998 - DOI
- https://doi.org/10.1007/s00247-025-06313-3
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