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Annals of Hematology

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01.03.2004 | Rapid Communications

Deletion (11)(q13) as the sole anomaly in myeloid malignancies: four new cases and a short review

verfasst von: Anna D. Panani, Vasiliki Pappa, Sotirios Papageorgiou, Francs Stamatelli, Sotirios A. Raptis

Erschienen in: Annals of Hematology | Ausgabe 3/2004

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Abstract

Chromosomal abnormalities are of significance in the study of hematologic malignancies. We describe one case of myelodysplastic syndrome (MDS) diagnosed 22 years ago as polycythemia vera (PV) as well as a case of unclassified myeloproliferative disease (MPD) with a poor clinical course. Both patients presented del(11)(q13) as the sole clonal abnormality. This abnormality was also found in two additional cases of MDS. Summarizing the literature, only ten other cases of myeloid malignancies with deletion of 11q involving band q13 as the sole anomaly have been reported. All but one of these cases presented interstitial deletions.

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Titel: Deletion (11)(q13) as the sole anomaly in myeloid malignancies: four new cases and a short review
verfasst von: Anna D. Panani
Vasiliki Pappa
Sotirios Papageorgiou
Francs Stamatelli
Sotirios A. Raptis
Publikationsdatum: 01.03.2004
Verlag: Springer-Verlag
Erschienen in: Annals of Hematology / Ausgabe 3/2004
Print ISSN: 0939-5555
Elektronische ISSN: 1432-0584
DOI: https://doi.org/10.1007/s00277-003-0823-x

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