Erschienen in:
24.10.2018 | Original Paper
Depressive Symptoms at HIV Testing and Two-Year All-Cause Mortality Among Men Who Inject Drugs in Vietnam
verfasst von:
Sara N. Levintow, Brian W. Pence, Tran Viet Ha, Nguyen Le Minh, Teerada Sripaipan, Carl A. Latkin, Pham The Vu, Vu Minh Quan, Constantine Frangakis, Vivian F. Go
Erschienen in:
AIDS and Behavior
|
Ausgabe 3/2019
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Abstract
People who inject drugs (PWID) with HIV experience an elevated risk of death. A potentially important determinant of survival is the high burden of depression. This study examined the relationship of depressive symptoms at HIV testing with 2-year all-cause mortality among newly diagnosed HIV-positive PWID in Vietnam. At HIV testing, 141 PWID (42%) experienced severe depressive symptoms, and over the 2 years following diagnosis, 82 PWID (24%) died. Controlling for potential confounders, the 2-year risk of death among those with depressive symptoms was 9.7% (95% CI − 1.2, 20.6%) higher than the risk among those without depressive symptoms. This increased risk of mortality for PWID with depressive symptoms was relatively consistent throughout the 2-year period: at 6, 12, and 18 months, the risk difference was 12.6% (5.5–19.7%), 13.9% (4.6–23.2%), and 11.0% (0.9–21.1%), respectively. HIV diagnosis may provide an important opportunity for depression screening and treatment, subsequently improving survival in this key population.
Trial registry: ClinicalTrials.gov NCT01689545.