Skip to main content
Erschienen in: Zeitschrift für Gerontologie und Geriatrie 2/2017

01.02.2017 | Gastritis | CME

Ulcus duodeni, Ulcus ventriculi und Helicobacter pylori

verfasst von: Prim. Dr. Peter Dovjak

Erschienen in: Zeitschrift für Gerontologie und Geriatrie | Ausgabe 2/2017

Einloggen, um Zugang zu erhalten

Zusammenfassung

Die Mortalität der Ulkuskrankheit ist bei Patienten im Alter über 80 Jahren im Fall von Komplikationen, wie Blutungen oder Perforationen, höher als bei der Gesamtbevölkerung. Mit einer Helicobacter-pylori-Infektion sind 90 % der Ulcera duodeni (UD) und 70 % der Ulcera ventriculi (UV) assoziiert. Die Behandlung älterer Patienten ist durch die oftmals begleitende Multimorbidität und Polypharmazie schwierig und bedarf einer geriatrischen Komplexbehandlung. Ulzera treten unter der Einnahme von nichtsteroidalen Antirheumatika (NSAR) oder Acetylsalicylsäure (ASS) häufig auf. Obschon Therapiefortschritte Prävalenz und Prognose der Erkrankung verbessert haben, stellt die Behandlung älterer Patienten mit einer Ulkuskrankheit (Ulcus duodeni und Ulcus ventriculi) eine Herausforderung dar.
Literatur
1.
Zurück zum Zitat Sung JJ, Kuipers EJ, El-Serag HB (2009) Systematic review: the global incidence and prevalence of peptic ulcer disease. Aliment Pharmacol Ther 29:938–946CrossRefPubMed Sung JJ, Kuipers EJ, El-Serag HB (2009) Systematic review: the global incidence and prevalence of peptic ulcer disease. Aliment Pharmacol Ther 29:938–946CrossRefPubMed
2.
Zurück zum Zitat Bartholomeeusen S, Vandenbroucke J, Truyers C, Buntinx F (2007) Time trends in the incidence of peptic ulcers and oesophagitis between 1994 and 2003. Br J Gen Pract 57:497–499PubMedPubMedCentral Bartholomeeusen S, Vandenbroucke J, Truyers C, Buntinx F (2007) Time trends in the incidence of peptic ulcers and oesophagitis between 1994 and 2003. Br J Gen Pract 57:497–499PubMedPubMedCentral
3.
Zurück zum Zitat Aro P, Storskrubb T, Ronkainen J, Bolling-Sternevald E, Engstrand L, Vieth M, Stolte M, Talley NJ, Agréus L (2006) Peptic ulcer disease in a general adult population: the Kalixanda study: a random population-based study. Am J Epidemiol 163:1025–1034CrossRefPubMed Aro P, Storskrubb T, Ronkainen J, Bolling-Sternevald E, Engstrand L, Vieth M, Stolte M, Talley NJ, Agréus L (2006) Peptic ulcer disease in a general adult population: the Kalixanda study: a random population-based study. Am J Epidemiol 163:1025–1034CrossRefPubMed
4.
Zurück zum Zitat Christensen S, Riis A, Nørgaard M, Sørensen HT, Thomsen RW (2007) Short-term mortality after perforated or bleeding peptic ulcer among elderly patients: a population-based cohort study. BMC Geriatr 7:8CrossRefPubMedPubMedCentral Christensen S, Riis A, Nørgaard M, Sørensen HT, Thomsen RW (2007) Short-term mortality after perforated or bleeding peptic ulcer among elderly patients: a population-based cohort study. BMC Geriatr 7:8CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Marshall BJ, McGechie DB, Rogers PA, Glancy RJ (1985) Pyloric Campylobacter infection and gastroduodenal disease. Med J Aust 142:439–444PubMed Marshall BJ, McGechie DB, Rogers PA, Glancy RJ (1985) Pyloric Campylobacter infection and gastroduodenal disease. Med J Aust 142:439–444PubMed
6.
Zurück zum Zitat Wang YK, Kuo FC, Liu CJ, Wu MC, Shih HY, Wang SS, Wu JY, Kuo CH, Huang YK, Wu DC (2015) Diagnosis of Helicobacter pylori infection: current options and developments. World J Gastroenterol 21:11221–11235CrossRefPubMedPubMedCentral Wang YK, Kuo FC, Liu CJ, Wu MC, Shih HY, Wang SS, Wu JY, Kuo CH, Huang YK, Wu DC (2015) Diagnosis of Helicobacter pylori infection: current options and developments. World J Gastroenterol 21:11221–11235CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Sonnenberg A (2007) Time trends of ulcer mortality in Europe. Gastroenterology 132:2320–2327CrossRefPubMed Sonnenberg A (2007) Time trends of ulcer mortality in Europe. Gastroenterology 132:2320–2327CrossRefPubMed
8.
Zurück zum Zitat Thorsen K, Søreide JA, Kvaløy JT, Glomsaker T, Søreide K (2013) Epidemiology of perforated peptic ulcer: age- and gender-adjusted analysis of incidence and mortality. World J Gastroenterol 19:347–354CrossRefPubMedPubMedCentral Thorsen K, Søreide JA, Kvaløy JT, Glomsaker T, Søreide K (2013) Epidemiology of perforated peptic ulcer: age- and gender-adjusted analysis of incidence and mortality. World J Gastroenterol 19:347–354CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Tsukanov VV, Kasparov EV, Tonkikh JL, Shtygasheva OV, Butorin NN, Amelchugova OS, Vasyutin AV, Bronnikova EP, Fassan M, Rugge M (2016) Peptic ulcer disease and Helicobacter pylori infection in different Siberian ethnicities. Helicobacter. doi:10.1111/hel.12322 PubMed Tsukanov VV, Kasparov EV, Tonkikh JL, Shtygasheva OV, Butorin NN, Amelchugova OS, Vasyutin AV, Bronnikova EP, Fassan M, Rugge M (2016) Peptic ulcer disease and Helicobacter pylori infection in different Siberian ethnicities. Helicobacter. doi:10.​1111/​hel.​12322 PubMed
10.
11.
Zurück zum Zitat Hsu CC, Hsu YC, Chang KH, Lee CY, Chong LW, Lin CL, Kao CH (2016) Association of dementia and peptic ulcer disease: a nationwide population-based study. Am J Alzheimers Dis Other Demen. doi:10.1177/1533317515617546 PubMed Hsu CC, Hsu YC, Chang KH, Lee CY, Chong LW, Lin CL, Kao CH (2016) Association of dementia and peptic ulcer disease: a nationwide population-based study. Am J Alzheimers Dis Other Demen. doi:10.​1177/​1533317515617546​ PubMed
12.
Zurück zum Zitat Hsu CC, Hsu YC, Chang KH, Lee CY, Chong LW, Lin CL, Shang CS, Sung FC, Kao CH (2015) Depression and the risk of peptic ulcer disease: a nationwide population-based study. Medicine (Baltimore) 94:e2333CrossRef Hsu CC, Hsu YC, Chang KH, Lee CY, Chong LW, Lin CL, Shang CS, Sung FC, Kao CH (2015) Depression and the risk of peptic ulcer disease: a nationwide population-based study. Medicine (Baltimore) 94:e2333CrossRef
13.
Zurück zum Zitat Wong CM, Tsang H, Lai HK, Thach TQ, Thomas GN, Chan KP, Lee SY, Ayres JG, Lam TH, Leung WK (2016) STROBE-long-term exposure to ambient fine particulate air pollution and hospitalization due to peptic ulcers. Medicine (Baltimore) 95:e3543CrossRef Wong CM, Tsang H, Lai HK, Thach TQ, Thomas GN, Chan KP, Lee SY, Ayres JG, Lam TH, Leung WK (2016) STROBE-long-term exposure to ambient fine particulate air pollution and hospitalization due to peptic ulcers. Medicine (Baltimore) 95:e3543CrossRef
14.
Zurück zum Zitat Lau JY, Sung J, Hill C, Henderson C, Howden CW, Metz DC (2011) Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion 84:102–113CrossRefPubMed Lau JY, Sung J, Hill C, Henderson C, Howden CW, Metz DC (2011) Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion 84:102–113CrossRefPubMed
15.
Zurück zum Zitat Pschyrembel W (2015) Pschyrembel Klinisches Wörterbuch, 266. Aufl. De Gruyter, Berlin Pschyrembel W (2015) Pschyrembel Klinisches Wörterbuch, 266. Aufl. De Gruyter, Berlin
16.
Zurück zum Zitat Moayyedi P, Forman D, Braunholtz D, Feltbower R, Crocombe W, Liptrott M, Axon A (2000) The proportion of upper gastrointestinal symptoms in the community associated with Helicobacter pylori, lifestyle factors, and nonsteroidal anti-inflammatory drugs. Leeds HELP Study Group. Am J Gastroenterol 95:1448–1455CrossRefPubMed Moayyedi P, Forman D, Braunholtz D, Feltbower R, Crocombe W, Liptrott M, Axon A (2000) The proportion of upper gastrointestinal symptoms in the community associated with Helicobacter pylori, lifestyle factors, and nonsteroidal anti-inflammatory drugs. Leeds HELP Study Group. Am J Gastroenterol 95:1448–1455CrossRefPubMed
17.
Zurück zum Zitat Laine L (2016) Upper gastrointestinal bleeding due to a peptic ulcer. N Engl J Med 374:2367–2376CrossRefPubMed Laine L (2016) Upper gastrointestinal bleeding due to a peptic ulcer. N Engl J Med 374:2367–2376CrossRefPubMed
18.
Zurück zum Zitat Moayyedi P, Talley NJ, Fennerty MB, Vakil N (2006) Can the clinical history distinguish between organic and functional dyspepsia? JAMA 295:1566–1576CrossRefPubMed Moayyedi P, Talley NJ, Fennerty MB, Vakil N (2006) Can the clinical history distinguish between organic and functional dyspepsia? JAMA 295:1566–1576CrossRefPubMed
19.
Zurück zum Zitat Dore MP, Pes GM, Bassotti G, Usai-Satta P (2016) Dyspepsia: when and how to test for Helicobacter pylori infection. Gastroenterol Res Pract 2016:8463614CrossRefPubMedPubMedCentral Dore MP, Pes GM, Bassotti G, Usai-Satta P (2016) Dyspepsia: when and how to test for Helicobacter pylori infection. Gastroenterol Res Pract 2016:8463614CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Roorda AK, Marcus SN, Triadafilopoulos G (2011) Algorithmic approach to patients presenting with heartburn and epigastric pain refractory to empiric proton pump inhibitor therapy. Dig Dis Sci 56:2871–2878CrossRefPubMed Roorda AK, Marcus SN, Triadafilopoulos G (2011) Algorithmic approach to patients presenting with heartburn and epigastric pain refractory to empiric proton pump inhibitor therapy. Dig Dis Sci 56:2871–2878CrossRefPubMed
21.
Zurück zum Zitat Buri L, Zullo A, Hassan C, Bersani G, Anti M, Bianco MA, Cipolletta L, Giulio ED, Matteo GD, Familiari L, Ficano L, Loriga P, Morini S, Pietropaolo V, Zambelli A, Grossi E, Tessari F, Intraligi M, Buscema M, Group SAW (2013) Upper GI endoscopy in elderly patients: predictive factors of relevant endoscopic findings. Intern Emerg Med 8:141–146CrossRefPubMed Buri L, Zullo A, Hassan C, Bersani G, Anti M, Bianco MA, Cipolletta L, Giulio ED, Matteo GD, Familiari L, Ficano L, Loriga P, Morini S, Pietropaolo V, Zambelli A, Grossi E, Tessari F, Intraligi M, Buscema M, Group SAW (2013) Upper GI endoscopy in elderly patients: predictive factors of relevant endoscopic findings. Intern Emerg Med 8:141–146CrossRefPubMed
22.
Zurück zum Zitat Nonaka M, Gotoda T, Kusano C, Fukuzawa M, Itoi T, Moriyasu F (2015) Safety of gastroenterologist-guided sedation with propofol for upper gastrointestinal therapeutic endoscopy in elderly patients compared with younger patients. Gut Liver 9:38–42CrossRefPubMed Nonaka M, Gotoda T, Kusano C, Fukuzawa M, Itoi T, Moriyasu F (2015) Safety of gastroenterologist-guided sedation with propofol for upper gastrointestinal therapeutic endoscopy in elderly patients compared with younger patients. Gut Liver 9:38–42CrossRefPubMed
23.
Zurück zum Zitat Travis AC, Pievsky D, Saltzman JR (2012) Endoscopy in the elderly. Am J Gastroenterol 107:1495–1501CrossRefPubMed Travis AC, Pievsky D, Saltzman JR (2012) Endoscopy in the elderly. Am J Gastroenterol 107:1495–1501CrossRefPubMed
24.
Zurück zum Zitat Mentis A, Lehours P, Mégraud F (2015) Epidemiology and diagnosis of Helicobacter pylori infection. Helicobacter 20(Suppl 1):1–7CrossRefPubMed Mentis A, Lehours P, Mégraud F (2015) Epidemiology and diagnosis of Helicobacter pylori infection. Helicobacter 20(Suppl 1):1–7CrossRefPubMed
25.
Zurück zum Zitat Chung CS, Chiang TH, Lee YC (2015) A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers. Korean J Intern Med 30:559–570CrossRefPubMedPubMedCentral Chung CS, Chiang TH, Lee YC (2015) A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers. Korean J Intern Med 30:559–570CrossRefPubMedPubMedCentral
27.
28.
Zurück zum Zitat Malmi H, Kautiainen H, Virta LJ, Färkkilä MA (2016) Increased short- and long-term mortality in 8146 hospitalised peptic ulcer patients. Aliment Pharmacol Ther. doi:10.1111/apt.13682 Malmi H, Kautiainen H, Virta LJ, Färkkilä MA (2016) Increased short- and long-term mortality in 8146 hospitalised peptic ulcer patients. Aliment Pharmacol Ther. doi:10.​1111/​apt.​13682
29.
Zurück zum Zitat Murata A, Mayumi T, Muramatsu K, Ohtani M, Matsuda S (2015) Effect of dementia on outcomes of elderly patients with hemorrhagic peptic ulcer disease based on a national administrative database. Aging Clin Exp Res 27:717–725CrossRefPubMed Murata A, Mayumi T, Muramatsu K, Ohtani M, Matsuda S (2015) Effect of dementia on outcomes of elderly patients with hemorrhagic peptic ulcer disease based on a national administrative database. Aging Clin Exp Res 27:717–725CrossRefPubMed
30.
Zurück zum Zitat Malfertheiner P, Megraud F, O’Morain CA, Atherton J, Axon AT, Bazzoli F, Gensini GF, Gisbert JP, Graham DY, Rokkas T, El-Omar EM, Kuipers EJ, Group EHS (2012) Management of Helicobacter pylori infection – the Maastricht IV/Florence Consensus Report. Gut 61:646–664CrossRefPubMed Malfertheiner P, Megraud F, O’Morain CA, Atherton J, Axon AT, Bazzoli F, Gensini GF, Gisbert JP, Graham DY, Rokkas T, El-Omar EM, Kuipers EJ, Group EHS (2012) Management of Helicobacter pylori infection – the Maastricht IV/Florence Consensus Report. Gut 61:646–664CrossRefPubMed
31.
Zurück zum Zitat Cizginer S, Ordulu Z, Kadayifci A (2014) Approach to Helicobacter pylori infection in geriatric population. World J Gastrointest Pharmacol Ther 5:139–147CrossRefPubMedPubMedCentral Cizginer S, Ordulu Z, Kadayifci A (2014) Approach to Helicobacter pylori infection in geriatric population. World J Gastrointest Pharmacol Ther 5:139–147CrossRefPubMedPubMedCentral
32.
Zurück zum Zitat Matsuzaki J, Hayashi R, Arakawa T, Ueno F, Kinoshita Y, Joh T, Takahashi S, Naito Y, Fukudo S, Chan FK, Hahm KB, Kachintorn U, Fock KM, Syam AF, Rani AA, Sollano JD, Zhu Q, Fujiwara Y, Kubota E, Kataoka H, Tokunaga K, Uchiyama K, Suzuki H, Group ITIGCSS (2016) Questionnaire-based survey on diagnostic and therapeutic endoscopies and H. pylori eradication for elderly patients in east asian countries. Digestion 93:93–102CrossRefPubMed Matsuzaki J, Hayashi R, Arakawa T, Ueno F, Kinoshita Y, Joh T, Takahashi S, Naito Y, Fukudo S, Chan FK, Hahm KB, Kachintorn U, Fock KM, Syam AF, Rani AA, Sollano JD, Zhu Q, Fujiwara Y, Kubota E, Kataoka H, Tokunaga K, Uchiyama K, Suzuki H, Group ITIGCSS (2016) Questionnaire-based survey on diagnostic and therapeutic endoscopies and H. pylori eradication for elderly patients in east asian countries. Digestion 93:93–102CrossRefPubMed
33.
Zurück zum Zitat Yuan JQ, Tsoi KK, Yang M, Wang JY, Threapleton DE, Yang ZY, Zou B, Mao C, Tang JL, Chan FK (2016) Systematic review with network meta-analysis: comparative effectiveness and safety of strategies for preventing NSAID-associated gastrointestinal toxicity. Aliment Pharmacol Ther 43:1262–1275CrossRefPubMed Yuan JQ, Tsoi KK, Yang M, Wang JY, Threapleton DE, Yang ZY, Zou B, Mao C, Tang JL, Chan FK (2016) Systematic review with network meta-analysis: comparative effectiveness and safety of strategies for preventing NSAID-associated gastrointestinal toxicity. Aliment Pharmacol Ther 43:1262–1275CrossRefPubMed
34.
Zurück zum Zitat Goldstein JL, Johanson JF, Hawkey CJ, Suchower LJ, Brown KA (2007) Clinical trial: healing of NSAID-associated gastric ulcers in patients continuing NSAID therapy – a randomized study comparing ranitidine with esomeprazole. Aliment Pharmacol Ther 26:1101–1111CrossRefPubMed Goldstein JL, Johanson JF, Hawkey CJ, Suchower LJ, Brown KA (2007) Clinical trial: healing of NSAID-associated gastric ulcers in patients continuing NSAID therapy – a randomized study comparing ranitidine with esomeprazole. Aliment Pharmacol Ther 26:1101–1111CrossRefPubMed
35.
Zurück zum Zitat Tang RS, Wu JC (2013) Managing peptic ulcer and gastroesophageal reflux disease in elderly Chinese patients – focus on esomeprazole. Clin Interv Aging 8:1433–1443PubMedPubMedCentral Tang RS, Wu JC (2013) Managing peptic ulcer and gastroesophageal reflux disease in elderly Chinese patients – focus on esomeprazole. Clin Interv Aging 8:1433–1443PubMedPubMedCentral
36.
Zurück zum Zitat Chan FK, Ching JY, Suen BY, Tse YK, Wu JC, Sung JJ (2013) Effects of Helicobacter pylori infection on long-term risk of peptic ulcer bleeding in low-dose aspirin users. Gastroenterology 144:528–535CrossRefPubMed Chan FK, Ching JY, Suen BY, Tse YK, Wu JC, Sung JJ (2013) Effects of Helicobacter pylori infection on long-term risk of peptic ulcer bleeding in low-dose aspirin users. Gastroenterology 144:528–535CrossRefPubMed
37.
Zurück zum Zitat Bhatt DL, Scheiman J, Abraham NS, Antman EM, Chan FK, Furberg CD, Johnson DA, Mahaffey KW, Quigley EM, Harrington RA, Bates ER, Bridges CR, Eisenberg MJ, Ferrari VA, Hlatky MA, Kaul S, Lindner JR, Moliterno DJ, Mukherjee D, Schofield RS, Rosenson RS, Stein JH, Weitz HH, Wesley DJ, Documents ACoCFTFoCEC (2008) ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol 52:1502–1517CrossRefPubMed Bhatt DL, Scheiman J, Abraham NS, Antman EM, Chan FK, Furberg CD, Johnson DA, Mahaffey KW, Quigley EM, Harrington RA, Bates ER, Bridges CR, Eisenberg MJ, Ferrari VA, Hlatky MA, Kaul S, Lindner JR, Moliterno DJ, Mukherjee D, Schofield RS, Rosenson RS, Stein JH, Weitz HH, Wesley DJ, Documents ACoCFTFoCEC (2008) ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol 52:1502–1517CrossRefPubMed
38.
Zurück zum Zitat Ciociola AA, McSorley DJ, Turner K, Sykes D, Palmer JB (1999) Helicobacter pylori infection rates in duodenal ulcer patients in the United States may be lower than previously estimated. Am J Gastroenterol 94:1834–1840CrossRefPubMed Ciociola AA, McSorley DJ, Turner K, Sykes D, Palmer JB (1999) Helicobacter pylori infection rates in duodenal ulcer patients in the United States may be lower than previously estimated. Am J Gastroenterol 94:1834–1840CrossRefPubMed
39.
Zurück zum Zitat Wong GL, Wong VW, Chan Y, Ching JY, Au K, Hui AJ, Lai LH, Chow DK, Siu DK, Lui YN, Wu JC, To KF, Hung LC, Chan HL, Sung JJ, Chan FK (2009) High incidence of mortality and recurrent bleeding in patients with Helicobacter pylori-negative idiopathic bleeding ulcers. Gastroenterology 137:525–531CrossRefPubMed Wong GL, Wong VW, Chan Y, Ching JY, Au K, Hui AJ, Lai LH, Chow DK, Siu DK, Lui YN, Wu JC, To KF, Hung LC, Chan HL, Sung JJ, Chan FK (2009) High incidence of mortality and recurrent bleeding in patients with Helicobacter pylori-negative idiopathic bleeding ulcers. Gastroenterology 137:525–531CrossRefPubMed
40.
Zurück zum Zitat Yu EW, Bauer SR, Bain PA, Bauer DC (2011) Proton pump inhibitors and risk of fractures: a meta-analysis of 11 international studies. Am J Med 124:519–526CrossRefPubMedPubMedCentral Yu EW, Bauer SR, Bain PA, Bauer DC (2011) Proton pump inhibitors and risk of fractures: a meta-analysis of 11 international studies. Am J Med 124:519–526CrossRefPubMedPubMedCentral
42.
43.
Zurück zum Zitat Yang YX, Metz DC (2010) Safety of proton pump inhibitor exposure. Gastroenterology 139:1115–1127CrossRefPubMed Yang YX, Metz DC (2010) Safety of proton pump inhibitor exposure. Gastroenterology 139:1115–1127CrossRefPubMed
44.
Zurück zum Zitat Moayyedi P, Soo S, Deeks J, Forman D, Harris A, Innes M, Delaney B (2003) Systematic review: antacids, H2-receptor antagonists, prokinetics, bismuth and sucralfate therapy for non-ulcer dyspepsia. Aliment Pharmacol Ther 17:1215–1227CrossRefPubMed Moayyedi P, Soo S, Deeks J, Forman D, Harris A, Innes M, Delaney B (2003) Systematic review: antacids, H2-receptor antagonists, prokinetics, bismuth and sucralfate therapy for non-ulcer dyspepsia. Aliment Pharmacol Ther 17:1215–1227CrossRefPubMed
45.
Zurück zum Zitat Thorsen K, Glomsaker TB, von Meer A, Søreide K, Søreide JA (2011) Trends in diagnosis and surgical management of patients with perforated peptic ulcer. J Gastrointest Surg 15:1329–1335CrossRefPubMedPubMedCentral Thorsen K, Glomsaker TB, von Meer A, Søreide K, Søreide JA (2011) Trends in diagnosis and surgical management of patients with perforated peptic ulcer. J Gastrointest Surg 15:1329–1335CrossRefPubMedPubMedCentral
46.
Zurück zum Zitat Nahon S, Hagège H, Latrive JP, Rosa I, Nalet B, Bour B, Faroux R, Gower P, Arpurt JP, Denis J, Henrion J, Rémy AJ, Pariente A, l’ANGH GdHDHd (2012) Epidemiological and prognostic factors involved in upper gastrointestinal bleeding: results of a French prospective multicenter study. Endoscopy 44:998–1008CrossRefPubMed Nahon S, Hagège H, Latrive JP, Rosa I, Nalet B, Bour B, Faroux R, Gower P, Arpurt JP, Denis J, Henrion J, Rémy AJ, Pariente A, l’ANGH GdHDHd (2012) Epidemiological and prognostic factors involved in upper gastrointestinal bleeding: results of a French prospective multicenter study. Endoscopy 44:998–1008CrossRefPubMed
47.
Zurück zum Zitat Laursen SB, Dalton HR, Murray IA et al. (2015) Performance of new thresholds of the Glasgow Blatchford Score in managing patients with upper gastrointestinal bleeding. Clin Gastroenterol hepatol 13(1):115–121(e2) Laursen SB, Dalton HR, Murray IA et al. (2015) Performance of new thresholds of the Glasgow Blatchford Score in managing patients with upper gastrointestinal bleeding. Clin Gastroenterol hepatol 13(1):115–121(e2)
48.
Zurück zum Zitat Laine L, McQuaid KR (2009) Endoscopic therapy for bleeding ulcers: an evidence-based approach based on meta-analyses of randomized controlled trials. Clin Gastroenterol Hepatol 7:31–47CrossRef Laine L, McQuaid KR (2009) Endoscopic therapy for bleeding ulcers: an evidence-based approach based on meta-analyses of randomized controlled trials. Clin Gastroenterol Hepatol 7:31–47CrossRef
49.
Zurück zum Zitat Lau JY, Sung JJ, Lam YH, Chan AC, Ng EK, Lee DW, Chan FK, Suen RC, Chung SC (1999) Endoscopic retreatment compared with surgery in patients with recurrent bleeding after initial endoscopic control of bleeding ulcers. N Engl J Med 340:751–756CrossRefPubMed Lau JY, Sung JJ, Lam YH, Chan AC, Ng EK, Lee DW, Chan FK, Suen RC, Chung SC (1999) Endoscopic retreatment compared with surgery in patients with recurrent bleeding after initial endoscopic control of bleeding ulcers. N Engl J Med 340:751–756CrossRefPubMed
Metadaten
Titel
Ulcus duodeni, Ulcus ventriculi und Helicobacter pylori
verfasst von
Prim. Dr. Peter Dovjak
Publikationsdatum
01.02.2017
Verlag
Springer Medizin
Erschienen in
Zeitschrift für Gerontologie und Geriatrie / Ausgabe 2/2017
Print ISSN: 0948-6704
Elektronische ISSN: 1435-1269
DOI
https://doi.org/10.1007/s00391-017-1190-x

Weitere Artikel der Ausgabe 2/2017

Zeitschrift für Gerontologie und Geriatrie 2/2017 Zur Ausgabe

Mitteilungen der DGG

Mitteilungen der DGG

Beiträge zum Themenschwerpunkt

Benzodiazepine absetzen im Alter

Journal Club

Journal Club

Mitteilungen der DGGG

Mitteilungen der DGGG

Magen-Darm-Erkrankungen in der Hausarztpraxis

Häufige gastrointestinale Krankheiten in der niedergelassenen Praxis sind Thema in diesem aufgezeichneten MMW-Webinar. Welche Differenzialdiagnosen bei Oberbauchbeschwerden sollten Sie kennen? Wie gelingt eine erfolgreiche probiotische Behandlung bei Reizdarm? Welche neuen Entwicklungen und praktischen Aspekte gibt es bei Diagnostik und Behandlung der chronisch entzündlichen Darmerkrankungen?