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Erschienen in: Archives of Orthopaedic and Trauma Surgery 6/2019

12.02.2019 | Orthopaedic Surgery

Design and preliminary biomechanical analysis of a novel motion preservation device for lumbar spinal disease after vertebral corpectomy

verfasst von: Jiantao Liu, Xijing He, Zhengchao Gao, Binbin Niu, Dongbo Lv, Yanzheng Gao

Erschienen in: Archives of Orthopaedic and Trauma Surgery | Ausgabe 6/2019

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Abstract

Objective

To design a novel prosthesis, a movable artificial lumbar complex (MALC), for non-fusion reconstruction after lumbar subtotal corpectomy and to evaluate the stability, range of motion and load-bearing strength in the human cadaveric lumbar spine.

Methods

Biomechanical tests were performed on lumbar spine specimens from 15 healthy cadavers which were divided in three groups: non-fusion, fusion and intact group. The range of motion (ROM), stability and load-bearing strength were measured.

Results

The prosthesis was composed of three parts: the upper and lower artificial lumbar discs and the middle artificial vertebra. Both the MALC and titanium mesh cage re-established vertebral height, and no spinal cord compression or prosthesis dislocation was observed at the operative level. Regarding stability, there was no significant difference in all directions between the intact group and non-fusion group (P > 0.05). Segment movements of the specimens in the non-fusion group revealed significantly decreased T12–L1 ROM and significantly increased L1–2 and L2–3 ROM in flexion/extension and lateral bending compared with those in the fusion group (P < 0.05). Regarding load-bearing strength, when the lumbar vertebra was ruptured, there was no damage to the MALC and titanium mesh cage, but the maximum load in the non-fusion group was larger (P > 0.05).

Conclusions

Compared with titanium cages, the MALC prosthesis not only restored the vertebral height and effectively preserved segment movements without any abnormal gain of mobility in adjacent inter-vertebral spaces but also bore the lumbar load and reduced the local stress load of adjacent vertebral endplates.
Literatur
1.
Zurück zum Zitat Chen B et al (2015) Comparison of the therapeutic efficacy of surgery with or without adjuvant radiotherapy versus radiotherapy alone for metastatic spinal cord compression: a meta-analysis. World Neurosurg 83(6):1066–1073CrossRefPubMed Chen B et al (2015) Comparison of the therapeutic efficacy of surgery with or without adjuvant radiotherapy versus radiotherapy alone for metastatic spinal cord compression: a meta-analysis. World Neurosurg 83(6):1066–1073CrossRefPubMed
2.
Zurück zum Zitat Wang H et al (2012) Epidemiology of spinal fractures among the elderly in Chongqing, China. Inj Int J Care Inj 43(12):2109–2116CrossRef Wang H et al (2012) Epidemiology of spinal fractures among the elderly in Chongqing, China. Inj Int J Care Inj 43(12):2109–2116CrossRef
3.
Zurück zum Zitat Bradford R et al (2017) Anterior lumbar corpectomy with expandable titanium cage reconstruction—a case series of 42 patients. World Neurosurg 108:317–324CrossRef Bradford R et al (2017) Anterior lumbar corpectomy with expandable titanium cage reconstruction—a case series of 42 patients. World Neurosurg 108:317–324CrossRef
4.
Zurück zum Zitat Kang C-N et al (2013) Anterior operation for unstable thoracolumbar and lumbar burst fractures tricortical autogenous iliac bone versus titanium mesh cage. J Spinal Disord Tech 26(7):E265–E271CrossRefPubMed Kang C-N et al (2013) Anterior operation for unstable thoracolumbar and lumbar burst fractures tricortical autogenous iliac bone versus titanium mesh cage. J Spinal Disord Tech 26(7):E265–E271CrossRefPubMed
5.
Zurück zum Zitat Pingel A, Castein J, Kandziora F (2017) Anterior monosegmental stabilization and fusion of an incomplete cranial burst fracture in the thoracolumbar spine via a mini-open, thoracoscopically assisted transthoracic approach. Eur Spine J 26:431–432CrossRefPubMed Pingel A, Castein J, Kandziora F (2017) Anterior monosegmental stabilization and fusion of an incomplete cranial burst fracture in the thoracolumbar spine via a mini-open, thoracoscopically assisted transthoracic approach. Eur Spine J 26:431–432CrossRefPubMed
6.
Zurück zum Zitat Scholz M et al. (2017) Prospective randomized controlled comparison of posterior vs. posterior–anterior stabilization of thoracolumbar incomplete cranial burst fractures in neurological intact patients: the RASPUTHINE pilot study. Eur Spine J 27:3016–3024CrossRefPubMed Scholz M et al. (2017) Prospective randomized controlled comparison of posterior vs. posterior–anterior stabilization of thoracolumbar incomplete cranial burst fractures in neurological intact patients: the RASPUTHINE pilot study. Eur Spine J 27:3016–3024CrossRefPubMed
7.
Zurück zum Zitat Liu P et al (2015) A retrospective controlled study of three different operative approaches for the treatment of thoracic and lumbar spinal tuberculosis: three years of follow-up. Clin Neurol Neurosurg 128:25–34CrossRefPubMed Liu P et al (2015) A retrospective controlled study of three different operative approaches for the treatment of thoracic and lumbar spinal tuberculosis: three years of follow-up. Clin Neurol Neurosurg 128:25–34CrossRefPubMed
8.
Zurück zum Zitat Zhang C et al (2016) Adjacent segment degeneration versus disease after lumbar spine fusion for degenerative pathology a systematic review with meta-analysis of the literature. Clin Spine Surg 29(1):21–29CrossRefPubMed Zhang C et al (2016) Adjacent segment degeneration versus disease after lumbar spine fusion for degenerative pathology a systematic review with meta-analysis of the literature. Clin Spine Surg 29(1):21–29CrossRefPubMed
9.
Zurück zum Zitat Pan A et al (2016) Adjacent segment degeneration after lumbar spinal fusion compared with motion-preservation procedures: a meta-analysis. Eur Spine J 25(5):1522–1532CrossRef Pan A et al (2016) Adjacent segment degeneration after lumbar spinal fusion compared with motion-preservation procedures: a meta-analysis. Eur Spine J 25(5):1522–1532CrossRef
10.
Zurück zum Zitat Kim H-J et al (2015) The influence of intrinsic disc degeneration of the adjacent segments on its stress distribution after one-level lumbar fusion. Eur Spine J 24(4):827–837CrossRefPubMed Kim H-J et al (2015) The influence of intrinsic disc degeneration of the adjacent segments on its stress distribution after one-level lumbar fusion. Eur Spine J 24(4):827–837CrossRefPubMed
11.
Zurück zum Zitat Lu S-b et al (2015) An 11-year minimum follow-up of the Charite III lumbar disc replacement for the treatment of symptomatic degenerative disc disease. Eur Spine J 24(9):2056–2064CrossRefPubMed Lu S-b et al (2015) An 11-year minimum follow-up of the Charite III lumbar disc replacement for the treatment of symptomatic degenerative disc disease. Eur Spine J 24(9):2056–2064CrossRefPubMed
12.
Zurück zum Zitat Wuertinger C et al (2017) Motion preservation following total lumbar disc replacement at the lumbosacral junction: a prospective long-term clinical and radiographic investigation. Spine J 18:72–80CrossRefPubMed Wuertinger C et al (2017) Motion preservation following total lumbar disc replacement at the lumbosacral junction: a prospective long-term clinical and radiographic investigation. Spine J 18:72–80CrossRefPubMed
13.
Zurück zum Zitat Ma Y-Z et al (2008) The mid- or long-term clinical results of prosthetic disc nucleus replacement in the treatment of lumbar disc disease. Zhonghua wai ke za zhi [Chinese journal of surgery] 46(5):350–353 Ma Y-Z et al (2008) The mid- or long-term clinical results of prosthetic disc nucleus replacement in the treatment of lumbar disc disease. Zhonghua wai ke za zhi [Chinese journal of surgery] 46(5):350–353
14.
Zurück zum Zitat Kashkoush A et al (2016) Evaluation of a hybrid dynamic stabilization and fusion system in the lumbar spine: a 10 year experience. Cureus 8(6):e637–e637PubMedPubMedCentral Kashkoush A et al (2016) Evaluation of a hybrid dynamic stabilization and fusion system in the lumbar spine: a 10 year experience. Cureus 8(6):e637–e637PubMedPubMedCentral
15.
Zurück zum Zitat Liu J et al (2017) Lumbar subtotal corpectomy non-fusion model produced using a novel prosthesis. Arch Orthop Trauma Surg 137(11):1467–1476CrossRefPubMed Liu J et al (2017) Lumbar subtotal corpectomy non-fusion model produced using a novel prosthesis. Arch Orthop Trauma Surg 137(11):1467–1476CrossRefPubMed
16.
Zurück zum Zitat Liu J, Li H, Niu B (2017) Design and activity analysis of bionic artificial lumbar vertebra and disc complex. Orthop Biomech Mater Clin Stud 14(2):5–10 Liu J, Li H, Niu B (2017) Design and activity analysis of bionic artificial lumbar vertebra and disc complex. Orthop Biomech Mater Clin Stud 14(2):5–10
17.
Zurück zum Zitat Lu T et al (2017) Single-level anterior cervical corpectomy and fusion using a new 3D-printed anatomy-adaptive titanium mesh cage for treatment of cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament: a retrospective case series study. Med Sci Monit 23:3105–3114CrossRefPubMedPubMedCentral Lu T et al (2017) Single-level anterior cervical corpectomy and fusion using a new 3D-printed anatomy-adaptive titanium mesh cage for treatment of cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament: a retrospective case series study. Med Sci Monit 23:3105–3114CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Wilke HJ, Wenger K, Claes L (1998) Testing criteria for spinal implants: recommendations for the standardization of in vitro stability testing of spinal implants. Eur Spine J 7(2):148–154CrossRefPubMedPubMedCentral Wilke HJ, Wenger K, Claes L (1998) Testing criteria for spinal implants: recommendations for the standardization of in vitro stability testing of spinal implants. Eur Spine J 7(2):148–154CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Disch AC et al (2007) Three-dimensional stiffness in a thoracolumbar en-bloc spondylectomy model: a biomechanical in vitro study. Clin Biomech 22(9):957–964CrossRef Disch AC et al (2007) Three-dimensional stiffness in a thoracolumbar en-bloc spondylectomy model: a biomechanical in vitro study. Clin Biomech 22(9):957–964CrossRef
21.
Zurück zum Zitat Wilke HJ, Kettler A, Claes LE (1997) Are sheep spines a valid biomechanical model for human spines? Spine 22(20):2365–2374CrossRefPubMed Wilke HJ, Kettler A, Claes LE (1997) Are sheep spines a valid biomechanical model for human spines? Spine 22(20):2365–2374CrossRefPubMed
22.
Zurück zum Zitat Ramirez JJ et al (2010) An expandable prosthesis with dual cage-and-plate function in a single device for vertebral body replacement: clinical experience on 14 cases with vertebral tumors. Arch Med Res 41(6):478–482CrossRefPubMed Ramirez JJ et al (2010) An expandable prosthesis with dual cage-and-plate function in a single device for vertebral body replacement: clinical experience on 14 cases with vertebral tumors. Arch Med Res 41(6):478–482CrossRefPubMed
23.
Zurück zum Zitat Khodadadyan-Klostermann C et al (2004) Expandable cages: biomechanical comparison of different cages for ventral spondylodesis in the thoracolumbar spine. Chirurg 75(7):694–701CrossRefPubMed Khodadadyan-Klostermann C et al (2004) Expandable cages: biomechanical comparison of different cages for ventral spondylodesis in the thoracolumbar spine. Chirurg 75(7):694–701CrossRefPubMed
24.
Zurück zum Zitat Penzkofer R et al (2011) Biomechanical comparison of the end plate design of three vertebral body replacement systems. Arch Orthop Trauma Surg 131(9):1253–1259CrossRefPubMed Penzkofer R et al (2011) Biomechanical comparison of the end plate design of three vertebral body replacement systems. Arch Orthop Trauma Surg 131(9):1253–1259CrossRefPubMed
25.
Zurück zum Zitat Vieweg U (2007) Vertebral body replacement system Synex in unstable burst fractures of the thoracic and lumbar spine. J Orthop Traumatol 8(2):64–70CrossRefPubMed Vieweg U (2007) Vertebral body replacement system Synex in unstable burst fractures of the thoracic and lumbar spine. J Orthop Traumatol 8(2):64–70CrossRefPubMed
26.
Zurück zum Zitat Qin J et al (2012) Artificial cervical vertebra and intervertebral complex replacement through the anterior approach in animal model: a biomechanical and in vivo evaluation of a successful goat model. PLoS One 7(12):e52910CrossRefPubMedPubMedCentral Qin J et al (2012) Artificial cervical vertebra and intervertebral complex replacement through the anterior approach in animal model: a biomechanical and in vivo evaluation of a successful goat model. PLoS One 7(12):e52910CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Dong J et al (2015) Artificial disc and vertebra system: a novel motion preservation device for cervical spinal disease after vertebral corpectomy. Clinics 70(7):493–499CrossRefPubMedPubMedCentral Dong J et al (2015) Artificial disc and vertebra system: a novel motion preservation device for cervical spinal disease after vertebral corpectomy. Clinics 70(7):493–499CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat Yu J, Liu L-T, Zhao J-N (2013) Design and preliminary biomechanical analysis of artificial cervical joint complex (vol 133, pg 735, 2013). Arch Orthop Trauma Surg 133(9):1329–1329CrossRef Yu J, Liu L-T, Zhao J-N (2013) Design and preliminary biomechanical analysis of artificial cervical joint complex (vol 133, pg 735, 2013). Arch Orthop Trauma Surg 133(9):1329–1329CrossRef
29.
Zurück zum Zitat Jang J-W et al (2014) Effect of posterior subsidence on cervical alignment after anterior cervical corpectomy and reconstruction using titanium mesh cages in degenerative cervical disease. J Clin Neurosci 21(10):1779–1785CrossRefPubMed Jang J-W et al (2014) Effect of posterior subsidence on cervical alignment after anterior cervical corpectomy and reconstruction using titanium mesh cages in degenerative cervical disease. J Clin Neurosci 21(10):1779–1785CrossRefPubMed
30.
Zurück zum Zitat Lu T et al (2017) Effects of titanium mesh cage end structures on the compressive load at the endplate interface: a cadaveric biomechanical study. Med Sci Monit 23:2863–2870CrossRefPubMedPubMedCentral Lu T et al (2017) Effects of titanium mesh cage end structures on the compressive load at the endplate interface: a cadaveric biomechanical study. Med Sci Monit 23:2863–2870CrossRefPubMedPubMedCentral
Metadaten
Titel
Design and preliminary biomechanical analysis of a novel motion preservation device for lumbar spinal disease after vertebral corpectomy
verfasst von
Jiantao Liu
Xijing He
Zhengchao Gao
Binbin Niu
Dongbo Lv
Yanzheng Gao
Publikationsdatum
12.02.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Archives of Orthopaedic and Trauma Surgery / Ausgabe 6/2019
Print ISSN: 0936-8051
Elektronische ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-018-03106-2

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