Detection of Molecular Alterations in Taiwanese Patients with Medullary Thyroid Cancer Using Whole-Exome Sequencing

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Zurück zum Zitat Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR (2010) A method and server for predicting damaging missense mutations. Nature methods 7 (4):248–249. https://doi.org/10.1038/nmeth0410-248 CrossRefPubMedPubMedCentral Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR (2010) A method and server for predicting damaging missense mutations. Nature methods 7 (4):248–249. https://​doi.​org/​10.​1038/​nmeth0410-248 CrossRefPubMedPubMedCentral

Zurück zum Zitat Kumar P, Henikoff S, Ng PC (2009) Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nature protocols 4 (7):1073–1081. https://doi.org/10.1038/nprot.2009.86 CrossRefPubMed Kumar P, Henikoff S, Ng PC (2009) Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nature protocols 4 (7):1073–1081. https://​doi.​org/​10.​1038/​nprot.​2009.​86 CrossRefPubMed

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Zurück zum Zitat Li MM, Datto M, Duncavage EJ, Kulkarni S, Lindeman NI, Roy S, Tsimberidou AM, Vnencak-Jones CL, Wolff DJ, Younes A, Nikiforova MN (2017) Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists. The Journal of molecular diagnostics: JMD 19 (1):4–23. https://doi.org/10.1016/j.jmoldx.2016.10.002 CrossRefPubMedPubMedCentral Li MM, Datto M, Duncavage EJ, Kulkarni S, Lindeman NI, Roy S, Tsimberidou AM, Vnencak-Jones CL, Wolff DJ, Younes A, Nikiforova MN (2017) Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists. The Journal of molecular diagnostics: JMD 19 (1):4–23. https://​doi.​org/​10.​1016/​j.​jmoldx.​2016.​10.​002 CrossRefPubMedPubMedCentral

Zurück zum Zitat Splinter D, Razafsky DS, Schlager MA, Serra-Marques A, Grigoriev I, Demmers J, Keijzer N, Jiang K, Poser I, Hyman AA, Hoogenraad CC, King SJ, Akhmanova A (2012) BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Molecular biology of the cell 23 (21):4226–4241. https://doi.org/10.1091/mbc.E12-03-0210 CrossRefPubMedPubMedCentral Splinter D, Razafsky DS, Schlager MA, Serra-Marques A, Grigoriev I, Demmers J, Keijzer N, Jiang K, Poser I, Hyman AA, Hoogenraad CC, King SJ, Akhmanova A (2012) BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Molecular biology of the cell 23 (21):4226–4241. https://​doi.​org/​10.​1091/​mbc.​E12-03-0210 CrossRefPubMedPubMedCentral

Zurück zum Zitat Rossor AM, Oates EC, Salter HK, Liu Y, Murphy SM, Schule R, Gonzalez MA, Scoto M, Phadke R, Sewry CA, Houlden H, Jordanova A, Tournev I, Chamova T, Litvinenko I, Zuchner S, Herrmann DN, Blake J, Sowden JE, Acsadi G, Rodriguez ML, Menezes MP, Clarke NF, Auer Grumbach M, Bullock SL, Muntoni F, Reilly MM, North KN (2015) Phenotypic and molecular insights into spinal muscular atrophy due to mutations in BICD2. Brain: a journal of neurology 138 (Pt 2):293–310. https://doi.org/10.1093/brain/awu356 CrossRef Rossor AM, Oates EC, Salter HK, Liu Y, Murphy SM, Schule R, Gonzalez MA, Scoto M, Phadke R, Sewry CA, Houlden H, Jordanova A, Tournev I, Chamova T, Litvinenko I, Zuchner S, Herrmann DN, Blake J, Sowden JE, Acsadi G, Rodriguez ML, Menezes MP, Clarke NF, Auer Grumbach M, Bullock SL, Muntoni F, Reilly MM, North KN (2015) Phenotypic and molecular insights into spinal muscular atrophy due to mutations in BICD2. Brain: a journal of neurology 138 (Pt 2):293–310. https://​doi.​org/​10.​1093/​brain/​awu356 CrossRef

Zurück zum Zitat Cavatorta AL, Di Gregorio A, Bugnon Valdano M, Marziali F, Cabral M, Bottai H, Cittadini J, Nocito AL, Gardiol D (2017) DLG1 polarity protein expression associates with the disease progress of low-grade cervical intraepithelial lesions. Experimental and molecular pathology 102 (1):65–69. https://doi.org/10.1016/j.yexmp.2016.12.008 CrossRefPubMed Cavatorta AL, Di Gregorio A, Bugnon Valdano M, Marziali F, Cabral M, Bottai H, Cittadini J, Nocito AL, Gardiol D (2017) DLG1 polarity protein expression associates with the disease progress of low-grade cervical intraepithelial lesions. Experimental and molecular pathology 102 (1):65–69. https://​doi.​org/​10.​1016/​j.​yexmp.​2016.​12.​008 CrossRefPubMed

Zurück zum Zitat Pekow J, Meckel K, Dougherty U, Huang Y, Chen X, Almoghrabi A, Mustafi R, Ayaloglu-Butun F, Deng Z, Haider HI, Hart J, Rubin DT, Kwon JH, Bissonnette M (2017) miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD. Clinical cancer research: an official journal of the American Association for Cancer Research 23 (17):5281–5291. https://doi.org/10.1158/1078-0432.ccr-17-0171 CrossRef Pekow J, Meckel K, Dougherty U, Huang Y, Chen X, Almoghrabi A, Mustafi R, Ayaloglu-Butun F, Deng Z, Haider HI, Hart J, Rubin DT, Kwon JH, Bissonnette M (2017) miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD. Clinical cancer research: an official journal of the American Association for Cancer Research 23 (17):5281–5291. https://​doi.​org/​10.​1158/​1078-0432.​ccr-17-0171 CrossRef

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Zurück zum Zitat Dhanoa BS, Cogliati T, Satish AG, Bruford EA, Friedman JS (2013) Update on the Kelch-like (KLHL) gene family. Human genomics 7:13. https://doi.org/10.1186/1479-7364-7-13 CrossRefPubMedPubMedCentral Dhanoa BS, Cogliati T, Satish AG, Bruford EA, Friedman JS (2013) Update on the Kelch-like (KLHL) gene family. Human genomics 7:13. https://​doi.​org/​10.​1186/​1479-7364-7-13 CrossRefPubMedPubMedCentral

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