Erschienen in:
01.04.2015 | Breast Oncology
Determining the Role of Gene Expression Assays in Local Therapy for Breast Cancer: First Steps with a Positive Impression
verfasst von:
Mackenzie Daly, MD
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 4/2015
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Excerpt
Determining when post-mastectomy radiation therapy (PMRT) should be utilized in breast cancer patients with T1 or T2 tumors and 1–3 positive lymph nodes is an area of uncertainty. In this patient population, balancing the benefits of improved local control and overall survival with the long-term complications of therapeutic radiation relies heavily on the ‘art of medicine’.
1,
2 The paper submitted by Dr. Jegadeesh and colleagues published in this issue of
Annals of Surgical Oncology suggests that the 21-gene recurrence score assay may be a tool to optimize local therapy for breast cancer patients. Furthermore, the authors offer a novel perspective on utilizing the recurrence score for clinical decision making.
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