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Erschienen in: Rheumatology International 12/2007

01.10.2007 | Case Report

Development of acute inflammatory arthritis by granulocyte-macrophage colony-stimulating factor during autologous stem cell transplantation for cryoglobulinemia

verfasst von: Olga Meltem Akay, Cengiz Korkmaz, Zafer Gulbas

Erschienen in: Rheumatology International | Ausgabe 12/2007

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Abstract

Hematopoietic growth factors (HGFs) are now known to influence the function of mature myeloid cells as well as their traditional roles as regulators of hematopoiesis. It became apparent that they could take part in inflammatory and immune responses by activating monocytes/macrophages to release mediators of such responses. We describe a 53-year-old male who developed acute inflammatory arthritis by granulocyte-macrophage colony-stimulating factor (GM-CSF) following autologous stem cell transplantation for cryoglobulinemia. Arthritis improved dramatically soon after GM-CSF was withdrawn and steroid therapy was admitted. This case may lead to further attention for this potential problem since HGFs are frequently used in a variety of clinical settings.
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Metadaten
Titel
Development of acute inflammatory arthritis by granulocyte-macrophage colony-stimulating factor during autologous stem cell transplantation for cryoglobulinemia
verfasst von
Olga Meltem Akay
Cengiz Korkmaz
Zafer Gulbas
Publikationsdatum
01.10.2007
Verlag
Springer-Verlag
Erschienen in
Rheumatology International / Ausgabe 12/2007
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-007-0345-2

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