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International Urogynecology Journal
Erschienen in: International Urogynecology Journal 9/2011

01.09.2011 | Review Article

Development of cellular therapy for the treatment of stress urinary incontinence

verfasst von: Hung-Jen Wang, Yao-Chi Chuang, Michael B. Chancellor

Erschienen in: International Urogynecology Journal | Ausgabe 9/2011

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Abstract

Stress urinary incontinence (SUI) is highly prevalent and associated with a reduced quality of life. An intact rhabdosphincter at the mid-urethra is mandatory to maintain urinary continence. Adult stem cell injection therapy for the regenerative repair of an impaired sphincter is currently at the forefront of incontinence research. The implanted cells will fuse with muscle and release trophic factors promoting nerve and muscle integration. Hereby, we review the use of mesenchymal stem cell therapy for SUI and the experience with the development of muscle-derived stem cells.
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Metadaten
Titel
Development of cellular therapy for the treatment of stress urinary incontinence
verfasst von
Hung-Jen Wang
Yao-Chi Chuang
Michael B. Chancellor
Publikationsdatum
01.09.2011
Verlag
Springer-Verlag
Erschienen in
International Urogynecology Journal / Ausgabe 9/2011
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-011-1432-1

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