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01.09.2014 | Original Article

Developmental dyscalculia: a dysconnection syndrome?

verfasst von: Karin Kucian, Simone Schwizer Ashkenazi, Jürgen Hänggi, Stephanie Rotzer, Lutz Jäncke, Ernst Martin, Michael von Aster

Erschienen in: Brain Structure and Function | Ausgabe 5/2014

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Abstract

Numerical understanding is important for everyday life. For children with developmental dyscalculia (DD), numbers and magnitudes present profound problems which are thought to be based upon neuronal impairments of key regions for numerical understanding. The aim of the present study was to investigate possible differences in white matter fibre integrity between children with DD and controls using diffusion tensor imaging. White matter integrity and behavioural measures were evaluated in 15 children with developmental dyscalculia aged around 10 years and 15 matched controls. The main finding, obtained by a whole brain group comparison, revealed reduced fractional anisotropy in the superior longitudinal fasciculus in children with developmental dyscalculia. In addition, a region of interest analysis exhibited prominent deficits in fibres of the superior longitudinal fasciculus adjacent to the intraparietal sulcus, which is thought to be the core region for number processing. To conclude, our results outline deficient fibre projection between parietal, temporal and frontal regions in children with developmental dyscalculia, and therefore raise the question of whether dyscalculia can be seen as a dysconnection syndrome. Since the superior longitudinal fasciculus is involved in the integration and control of distributed brain processes, the present results highlight the importance of considering broader domain-general mechanisms in the diagnosis and therapy of dyscalculia.

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Titel: Developmental dyscalculia: a dysconnection syndrome?
verfasst von: Karin Kucian
Simone Schwizer Ashkenazi
Jürgen Hänggi
Stephanie Rotzer
Lutz Jäncke
Ernst Martin
Michael von Aster
Publikationsdatum: 01.09.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Brain Structure and Function / Ausgabe 5/2014
Print ISSN: 1863-2653
Elektronische ISSN: 1863-2661
DOI: https://doi.org/10.1007/s00429-013-0597-4

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