Diabetologia

Up front

Metabolic surgery for the treatment of type 2 diabetes in obese individuals

David E. Cummings, Francesco Rubino

Medication use for the treatment of diabetes in obese individuals

John P. H. Wilding

Translating aetiological insight into sustainable management of type 2 diabetes

Roy Taylor, Alison C. Barnes

Enteroendocrine K and L cells in healthy and type 2 diabetic individuals

Tina Jorsal, Nicolai A. Rhee, Jens Pedersen, Camilla D. Wahlgren, Brynjulf Mortensen, Sara L. Jepsen, Jacob Jelsing, Louise S. Dalbøge, Peter Vilmann, Hazem Hassan, Jakob W. Hendel, Steen S. Poulsen, Jens J. Holst, Tina Vilsbøll, Filip K. Knop

Long-term follow-up of intensive glycaemic control on renal outcomes in the Veterans Affairs Diabetes Trial (VADT)

Lily Agrawal, Nasrin Azad, Gideon D. Bahn, Ling Ge, Peter D. Reaven, Rodney A. Hayward, Domenic J. Reda, Nicholas V. Emanuele

The association between Helicobacter pylori seropositivity and risk of new-onset diabetes: a prospective cohort study

Mengge Zhou, Jing Liu, Yue Qi, Miao Wang, Ying Wang, Fan Zhao, Yongchen Hao, Dong Zhao

Dietary antioxidant capacity and risk of type 2 diabetes in the large prospective E3N-EPIC cohort

Francesca Romana Mancini, Aurélie Affret, Courtney Dow, Beverley Balkau, Fabrice Bonnet, Marie-Christine Boutron-Ruault, Guy Fagherazzi

Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis

Nicola M. McKeown, Hassan S. Dashti, Jiantao Ma, Danielle E. Haslam, Jessica C. Kiefte-de Jong, Caren E. Smith, Toshiko Tanaka, Mariaelisa Graff, Rozenn N. Lemaitre, Denis Rybin, Emily Sonestedt, Alexis C. Frazier-Wood, Dennis O. Mook-Kanamori, Yanping Li, Carol A. Wang, Elisabeth T. M. Leermakers, Vera Mikkilä, Kristin L. Young, Kenneth J. Mukamal, L. Adrienne Cupples, Christina-Alexandra Schulz, Tzu-An Chen, Ruifang Li-Gao, Tao Huang, Wendy H. Oddy, Olli Raitakari, Kenneth Rice, James B. Meigs, Ulrika Ericson, Lyn M. Steffen, Frits R. Rosendaal, Albert Hofman, Mika Kähönen, Bruce M. Psaty, Louise Brunkwall, Andre G. Uitterlinden, Jorma Viikari, David S. Siscovick, Ilkka Seppälä, Kari E. North, Dariush Mozaffarian, Josée Dupuis, Marju Orho-Melander, Stephen S. Rich, Renée de Mutsert, Lu Qi, Craig E. Pennell, Oscar H. Franco, Terho Lehtimäki, Mark A. Herman

Incident diabetes mellitus may explain the association between sleep duration and incident coronary heart disease

Akiko Kishi Svensson, Thomas Svensson, Mariusz Kitlinski, Peter Almgren, Gunnar Engström, Peter M. Nilsson, Olle Melander

Why childhood-onset type 1 diabetes impacts labour market outcomes: a mediation analysis

Sofie Persson, Gisela Dahlquist, Ulf-G. Gerdtham, Katarina Steen Carlsson

DNA methylation markers associated with type 2 diabetes, fasting glucose and HbA1c levels: a systematic review and replication in a case–control sample of the Lifelines study

Eliza Walaszczyk, Mirjam Luijten, Annemieke M. W. Spijkerman, Marc J. Bonder, Helen L. Lutgers, Harold Snieder, Bruce H. R. Wolffenbuttel, Jana V. van Vliet-Ostaptchouk

Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity

Michele Longo, Gregory A. Raciti, Federica Zatterale, Luca Parrillo, Antonella Desiderio, Rosa Spinelli, Ann Hammarstedt, Shahram Hedjazifar, Jenny M. Hoffmann, Cecilia Nigro, Paola Mirra, Francesca Fiory, Pietro Formisano, Claudia Miele, Ulf Smith, Francesco Beguinot

Enterovirus-associated changes in blood transcriptomic profiles of children with genetic susceptibility to type 1 diabetes

Niina Lietzen, Le T. T. An, Maria K. Jaakkola, Henna Kallionpää, Sami Oikarinen, Juha Mykkänen, Mikael Knip, Riitta Veijola, Jorma Ilonen, Jorma Toppari, Heikki Hyöty, Riitta Lahesmaa, Laura L. Elo

Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice

Alix Besançon, Tania Goncalves, Fabrice Valette, Mattias S. Dahllöf, Thomas Mandrup-Poulsen, Lucienne Chatenoud, Sylvaine You

Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes

Anaïs Szpigel, Isabelle Hainault, Aurélie Carlier, Nicolas Venteclef, Anne-Françoise Batto, Eric Hajduch, Catherine Bernard, Alain Ktorza, Jean-François Gautier, Pascal Ferré, Olivier Bourron, Fabienne Foufelle

GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study

Lærke S. Gasbjerg, Mikkel B. Christensen, Bolette Hartmann, Amalie R. Lanng, Alexander H. Sparre-Ulrich, Maria B. N. Gabe, Flemming Dela, Tina Vilsbøll, Jens J. Holst, Mette M. Rosenkilde, Filip K. Knop

FAK tyrosine phosphorylation is regulated by AMPK and controls metabolism in human skeletal muscle

David G. Lassiter, Carolina Nylén, Rasmus J. O. Sjögren, Alexander V. Chibalin, Harriet Wallberg-Henriksson, Erik Näslund, Anna Krook, Juleen R. Zierath

α-linolenic acid supplementation prevents exercise-induced improvements in white adipose tissue mitochondrial bioenergetics and whole-body glucose homeostasis in obese Zucker rats

Cynthia M.F. Monaco, Ross Proudfoot, Paula M. Miotto, Eric A.F. Herbst, Rebecca E.K. MacPherson, Graham P. Holloway

Acute renal metabolic effect of metformin assessed with hyperpolarised MRI in rats

Haiyun Qi, Per M. Nielsen, Marie Schroeder, Lotte B. Bertelsen, Fredrik Palm, Christoffer Laustsen

Aortic stiffness and ambulatory blood pressure as predictors of diabetic kidney disease: a competing risks analysis from the Rio de Janeiro Type 2 Diabetes Cohort Study

Claudia R. L. Cardoso, Nathalie C. Leite, Guilherme C. Salles, Marcel T. Ferreira, Gil F. Salles

Impact of prolonged overfeeding on skeletal muscle mitochondria in healthy individuals

Frederico G. S. Toledo, Darcy L. Johannsen, Jeffrey D. Covington, Sudip Bajpeyi, Bret Goodpaster, Kevin E. Conley, Eric Ravussin

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes

Virginia M. Stone, Minna M. Hankaniemi, Emma Svedin, Amirbabak Sioofy-Khojine, Sami Oikarinen, Heikki Hyöty, Olli H. Laitinen, Vesa P. Hytönen, Malin Flodström-Tullberg

Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes

Gareth S. D. Purvis, Fausto Chiazza, Jianmin Chen, Rodrigo Azevedo-Loiola, Lukas Martin, Dennis H. M. Kusters, Chris Reutelingsperger, Nikolaos Fountoulakis, Luigi Gnudi, Muhammed M. Yaqoob, Massimo Collino, Christoph Thiemermann, Egle Solito

Exercise training response heterogeneity: statistical insights

Greg Atkinson, Philip Williamson, Alan M. Batterham

Correction to: Soluble CD163, adiponectin, C-reactive protein and progression of dysglycaemia in individuals at high risk of type 2 diabetes mellitus: the ADDITION-PRO cohort

Pia Deichgræber, Daniel R. Witte, Holger J. Møller, Mette V. Skriver, Bjørn Richelsen, Marit E. Jørgensen, Nanna B. Johansen, Annelli Sandbæk

Correction to: Pioglitazone reduces cold-induced brown fat glucose uptake despite induction of browning in cultured human adipocytes: a randomised, controlled trial in humans

Rebecca K. C. Loh, Melissa F. Formosa, Nina Eikelis, David A. Bertovic, Mitchell J. Anderson, Shane A. Barwood, Shane Nanayakkara, Neale D. Cohen, Andre La Gerche, Anne T. Reutens, Kenneth S. Yap, Thomas W. Barber, Gavin W. Lambert, Martin H. Cherk, Stephen J. Duffy, Bronwyn A. Kingwell, Andrew L. Carey

Correction to: Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes

Toma Keser, Ivan Gornik, Frano Vučković, Najda Selak, Tamara Pavić, Edita Lukić, Ivan Gudelj, Hrvoje Gašparović, Bojan Biočina, Therese Tilin, Annika Wennerström, Satu Männistö, Veikko Salomaa, Aki Havulinna, Wei Wang, James F. Wilson, Nish Chaturvedi, Markus Perola, Harry Campbell, Gordan Lauc, Olga Gornik