Diabetologia

Diabetes quantitative trait locus research: from physiology to genetics and back

D. Gauguier

Effects of metformin and thiazolidinediones on suppression of hepatic glucose production and stimulation of glucose uptake in type 2 diabetes: a systematic review

A. Natali, E. Ferrannini

Insulin glargine or NPH combined with metformin in type 2 diabetes: the LANMET study

H. Yki-Järvinen, R. Kauppinen-Mäkelin, M. Tiikkainen, M. Vähätalo, H. Virtamo, K. Nikkilä, T. Tulokas, S. Hulme, K. Hardy, S. McNulty, J. Hänninen, H. Levänen, S. Lahdenperä, R. Lehtonen, L. Ryysy

Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans

J. J. Meier, A. Gethmann, O. Götze, B. Gallwitz, J. J. Holst, W. E. Schmidt, M. A. Nauck

The effect of conjugated equine oestrogen on diabetes incidence: the Women’s Health Initiative randomised trial

D. E. Bonds, N. Lasser, L. Qi, R. Brzyski, B. Caan, G. Heiss, M. C. Limacher, J. H. Liu, E. Mason, A. Oberman, M. J. O’Sullivan, L. S. Phillips, R. J. Prineas, L. Tinker

How to screen for depression and emotional problems in patients with diabetes: comparison of screening characteristics of depression questionnaires, measurement of diabetes-specific emotional problems and standard clinical assessment

N. Hermanns, B. Kulzer, M. Krichbaum, T. Kubiak, T. Haak

Preterm birth and later insulin resistance: effects of birth weight and postnatal growth in a population based longitudinal study from birth into adult life

M. J. J. Finken, M. G. Keijzer-Veen, F. W. Dekker, M. Frölich, E. T. M. Hille, J. A. Romijn, J. M. Wit

Major quantitative trait locus on chromosome 2 for glucose tolerance in diabetic SMXA-5 mouse established from non-diabetic SM/J and A/J strains

M. Kobayashi, F. Io, T. Kawai, M. Kumazawa, H. Ikegami, M. Nishimura, T. Ohno, F. Horio

Increased risk of obesity associated with the variant allele of the PPARGC1A Gly482Ser polymorphism in physically inactive elderly men

M. Ridderstråle, L. E. Johansson, L. Rastam, U. Lindblad

Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes

I. Barroso, J. Luan, M. S. Sandhu, P. W. Franks, V. Crowley, A. J. Schafer, S. O’Rahilly, N. J. Wareham

Activin receptor-like kinase 7 induces apoptosis of pancreatic beta cells and beta cell lines

N. Zhang, M. Kumar, G. Xu, W. Ju, T. Yoon, E. Xu, X. Huang, H. Gaisano, C. Peng, Q. Wang

Downregulation of protein kinase B/Akt-1 mediates INS-1 insulinoma cell apoptosis induced by dominant-negative suppression of hepatocyte nuclear factor-1alpha function

H. Wobser, C. Bonner, J. J. Nolan, M. M. Byrne, J. H. M. Prehn

The effect of sensitisation to insulin with pioglitazone on fasting and postprandial lipid metabolism, lipoprotein modification by lipases, and lipid transfer activities in type 2 diabetic patients

K. Al Majali, M. B. Cooper, B. Staels, G. Luc, M-R. Taskinen, D. J. Betteridge

In treatment-naïve and antiretroviral-treated subjects with HIV, reduced plasma adiponectin is associated with a reduced fractional clearance rate of VLDL, IDL and LDL apolipoprotein B-100

S. Das, M. Shahmanesh, M. Stolinski, F. Shojaee-Moradie, W. Jefferson, N. C. Jackson, M. Cobbold, P. Nightingale, A. M. Umpleby

Differences in protein and energy metabolism following portal versus systemic administration of insulin in diabetic dogs

E.-J. Freyse, U. Fischer, S. Knospe, G. C. Ford, K. S. Nair

Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice

M. Simmgen, C. Knauf, M. Lopez, A. I. Choudhury, M. Charalambous, J. Cantley, D. C. Bedford, M. Claret, M. A. Iglesias, H. Heffron, P. D. Cani, A. Vidal-Puig, R. Burcelin, D. J. Withers

Cyclooxygenase-2 (PTGS2) inhibitors augment the rate of hexose transport in L6 myotubes in an insulin- and AMPKα-independent manner

E. Alpert, A. Gruzman, B. Lardi-Studler, G. Cohen, R. Reich, S. Sasson

Ethnic differences in beta cell adaptation to insulin resistance in obese children and adolescents

R. Weiss, J. D. Dziura, T. S. Burgert, S. E. Taksali, W. V. Tamborlane, S. Caprio

Phosphorylation of c-Jun N-terminal kinase (JNK) in sensory neurones of diabetic rats, with possible effects on nerve conduction and neuropathic pain: prevention with an aldose reductase inhibitor

A. B. Middlemas, S. Agthong, D. R. Tomlinson

Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver

G. Bryzgalova, H. Gao, B. Ahren, J.R. Zierath, D. Galuska, T.L. Steiler, K. Dahlman-Wright, S. Nilsson, J.-Å. Gustafsson, S. Efendic, A. Khan

Intracellular sodium increase and susceptibility to ischaemia in hearts from type 2 diabetic db/db mice

R. Anzawa, M. Bernard, S. Tamareille, D. Baetz, S. Confort-Gouny, J. P. Gascard, P. Cozzone, D. Feuvray

Comment to: Patti ME, Mcmahon G, Mun EC et al. (2005) Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia. Diabetologia 48:2236–2240

J. J. Meier, M. A. Nauck, P. C. Butler

Reply to comment on: Patti ME, McMahon G, Mun EC et al. (2005) Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia. Diabetologia 48:2236–2240

M. E. Patti, S. Bonner-Weir, A. Goldfine

To: Gerstein HC, Pogue J, Mann JFE, Lonn E, Dagenais GR, McQueen M, Yusuf S, for the HOPE investigators (2005) The relationship between dysglycaemia and cardiovascular and renal risk in diabetic and non-diabetic participants in the HOPE study: a prospective epidemiological analysis. Diabetologia 48:1749–1755

John S. Yudkin

Reply to comment on: Gerstein HC, Pogue J, Mann JFE et al. (2005) The relationship between dysglycaemia and cardiovascular and renal risk in diabetic and non-diabetic participants in the HOPE study: a prospective epidemiological analysis. Diabetologia 48:1749–1755

H. C. Gerstein

Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes

Z. Asghar, D. Yau, F. Chan, D. LeRoith, C. B. Chan, M. B. Wheeler

Announcing up to euro 300,000 for the creation of one or more resources to facilitate diabetes research in Europe