Diabetologia

Up Front

Lelio Orci 1937–2019

Roberto Montesano, Alain Perrelet

Sex differences in metabolic regulation and diabetes susceptibility

Blandine Tramunt, Sarra Smati, Naia Grandgeorge, Françoise Lenfant, Jean-François Arnal, Alexandra Montagner, Pierre Gourdy

Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes

Ivy C. Mason, Jingyi Qian, Gail K. Adler, Frank A. J. L. Scheer

Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised controlled clinical trial

Rory J. McCrimmon, Andrei-Mircea Catarig, Juan P. Frias, Nanna L. Lausvig, Carel W. le Roux, Desirée Thielke, Ildiko Lingvay

A pragmatic and scalable strategy using mobile technology to promote sustained lifestyle changes to prevent type 2 diabetes in India and the UK: a randomised controlled trial

Arun Nanditha, Hazel Thomson, Priscilla Susairaj, Weerachai Srivanichakorn, Nick Oliver, Ian F. Godsland, Azeem Majeed, Ara Darzi, Krishnamoorthy Satheesh, Mary Simon, Arun Raghavan, Ramachandran Vinitha, Chamukuttan Snehalatha, Kate Westgate, Soren Brage, Stephen J. Sharp, Nicholas J. Wareham, Desmond G. Johnston, Ambady Ramachandran

Cord blood metabolic markers are strong mediators of the effect of maternal adiposity on fetal growth in pregnancies across the glucose tolerance spectrum: the PANDORA study

I-Lynn Lee, Elizabeth L. M. Barr, Danielle Longmore, Federica Barzi, Alex D. H. Brown, Christine Connors, Jacqueline A. Boyle, Marie Kirkwood, Vanya Hampton, Michael Lynch, Zhong X. Lu, Kerin O’Dea, Jeremy Oats, H. David McIntyre, Paul Zimmet, Jonathan E. Shaw, Louise J. Maple-Brown

Preterm birth and risk of type 1 and type 2 diabetes: a national cohort study

Casey Crump, Jan Sundquist, Kristina Sundquist

Age of obesity onset, cumulative obesity exposure over early adulthood and risk of type 2 diabetes

Juhua Luo, Allison Hodge, Michael Hendryx, Julie E. Byles

A comparison of obesity indices in relation to mortality in type 2 diabetes: the Fremantle Diabetes Study

Joel Tate, Matthew Knuiman, Wendy A. Davis, Timothy M. E. Davis, David G. Bruce

Association of moderate and vigorous physical activity with incidence of type 2 diabetes and subsequent mortality: 27 year follow-up of the Whitehall II study

Manasa S. Yerramalla, Aurore Fayosse, Aline Dugravot, Adam G. Tabak, Mika Kivimäki, Archana Singh-Manoux, Séverine Sabia

Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates

Marika Bogdani, Cate Speake, Mathew J. Dufort, Pamela Y. Johnson, Megan J. Larmore, Anthony J. Day, Thomas N. Wight, Åke Lernmark, Carla J. Greenbaum

PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice

Yi-Chun Chen, Richard E. Mains, Betty A. Eipper, Brad G. Hoffman, Traci A. Czyzyk, John E. Pintar, C. Bruce Verchere

Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway

Jun Shirakawa, Kazuki Tajima, Tomoko Okuyama, Mayu Kyohara, Yu Togashi, Dario F. De Jesus, Giorgio Basile, Tatsuya Kin, A. M. James Shapiro, Rohit N. Kulkarni, Yasuo Terauchi

The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening

Laura M. Jacobsen, Laura Bocchino, Carmella Evans-Molina, Linda DiMeglio, Robin Goland, Darrell M. Wilson, Mark A. Atkinson, Tandy Aye, William E. Russell, John M. Wentworth, David Boulware, Susan Geyer, Jay M. Sosenko

Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial

Pieter F. de Groot, Tatjana Nikolic, Sultan Imangaliyev, Siroon Bekkering, Gaby Duinkerken, Fleur M. Keij, Hilde Herrema, Maaike Winkelmeijer, Jeffrey Kroon, Evgeni Levin, Barbara Hutten, Elles M. Kemper, Suat Simsek, Johannes H. M. Levels, Flora A. van Hoorn, Renuka Bindraban, Alicia Berkvens, Geesje M. Dallinga-Thie, Mark Davids, Frits Holleman, Joost B. L. Hoekstra, Erik S. G. Stroes, Mihai Netea, Daniël H. van Raalte, Bart O. Roep, Max Nieuwdorp

A single bout of resistance exercise improves postprandial lipid metabolism in overweight/obese men with prediabetes

Adam J. Bittel, Daniel C. Bittel, Bettina Mittendorfer, Bruce W. Patterson, Adewole L. Okunade, Jun Yoshino, Lane C. Porter, Nada A. Abumrad, Dominic N. Reeds, W. Todd Cade

Type 2 diabetes does not account for ethnic differences in exercise capacity or skeletal muscle function in older adults

Siana Jones, Therese Tillin, Suzanne Williams, Sophie V. Eastwood, Alun D. Hughes, Nishi Chaturvedi

Predicting renal disease progression in a large contemporary cohort with type 1 diabetes mellitus

Marco Colombo, Stuart J. McGurnaghan, Samira Bell, Finlay MacKenzie, Alan W. Patrick, John R. Petrie, John A. McKnight, Sandra MacRury, Jamie Traynor, Wendy Metcalfe, Paul M. McKeigue, Helen M. Colhoun

Incidence and relative risk of renal replacement therapy in people with and without diabetes between 2002 and 2016 in a German region

Maria Narres, Heiner Claessen, Tatjana Kvitkina, Michael Koch, Lars Christian Rump, Thomas Weinreich, Andrea Icks

Geospatial mapping and data linkage uncovers variability in outcomes of foot disease according to multiple deprivation: a population cohort study of people with diabetes

Joanne E. Hurst, Ruth Barn, Lesley Gibson, Hamish Innes, Sicco A. Bus, Brian Kennon, David Wylie, James Woodburn