Skip to main content
Erschienen in: Uro-News 3/2022

07.03.2022 | Hodentumoren | Fortbildung

Residualtumoren beim metastasierten Hodentumor

Wie lassen sich maligne und benigne Befunde unterscheiden?

verfasst von: PD Dr. med. Tim Nestler, Prof. Dr. med. Dr. h. c. Axel Heidenreich

Erschienen in: Uro-News | Ausgabe 3/2022

Einloggen, um Zugang zu erhalten

Auszug

Im Hinblick auf Residualtumoren metastasierter Hodentumoren stellt sich immer wieder die Frage, ob die Bildgebung maligne Befunde oder lediglich Nekrosen und Narben zeigt. Um eine Übertherapie zu vermeiden, gilt es, die präoperative Diagnostik zu optimieren. …
Literatur
1.
Zurück zum Zitat Albers P et al. Guidelines on Testicular Cancer: 2015 Update. Eur Urol. 2015; 68: 1054-68 Albers P et al. Guidelines on Testicular Cancer: 2015 Update. Eur Urol. 2015; 68: 1054-68
2.
Zurück zum Zitat Heidenreich A et al. Surgical management of complex residual masses following systemic chemotherapy for metastatic testicular germ cell tumours. Ann Oncol. 2017; 28: 362-7 Heidenreich A et al. Surgical management of complex residual masses following systemic chemotherapy for metastatic testicular germ cell tumours. Ann Oncol. 2017; 28: 362-7
3.
Zurück zum Zitat Winter C et al. Residual tumor size and IGCCCG risk classification predict additional vascular procedures in patients with germ cell tumors and residual tumor resection: a multicenter analysis of the German Testicular Cancer Study Group. Eur Urol. 2012; 61: 403-9 Winter C et al. Residual tumor size and IGCCCG risk classification predict additional vascular procedures in patients with germ cell tumors and residual tumor resection: a multicenter analysis of the German Testicular Cancer Study Group. Eur Urol. 2012; 61: 403-9
4.
Zurück zum Zitat Nini A et al. Surgical management and outcomes of patients with bone metastases in germ cell tumors: A case series. Urol Oncol. 2018; 36: 82 e1-5 Nini A et al. Surgical management and outcomes of patients with bone metastases in germ cell tumors: A case series. Urol Oncol. 2018; 36: 82 e1-5
5.
Zurück zum Zitat Carver BS et al. Long-term clinical outcome after postchemotherapy retroperitoneal lymph node dissection in men with residual teratoma. J Clin Oncol. 2007; 25: 1033-7 Carver BS et al. Long-term clinical outcome after postchemotherapy retroperitoneal lymph node dissection in men with residual teratoma. J Clin Oncol. 2007; 25: 1033-7
6.
Zurück zum Zitat Steyerberg EW et al. Prediction of residual retroperitoneal mass histology after chemotherapy for metastatic nonseminomatous germ cell tumor: multivariate analysis of individual patient data from six study groups. J Clin Oncol. 1995; 13: 1177-87 Steyerberg EW et al. Prediction of residual retroperitoneal mass histology after chemotherapy for metastatic nonseminomatous germ cell tumor: multivariate analysis of individual patient data from six study groups. J Clin Oncol. 1995; 13: 1177-87
7.
Zurück zum Zitat Mao Y et al. Predictive models for lymph node metastases in patients with testicular germ cell tumors. Abdom Imaging. 2015; 40: 3196-205 Mao Y et al. Predictive models for lymph node metastases in patients with testicular germ cell tumors. Abdom Imaging. 2015; 40: 3196-205
8.
Zurück zum Zitat Onozawa M et al. Clinical parameters that predict histology of postchemotherapy retroperitoneal lymph node mass in testicular cancer. Int J Urol. 2004; 11: 535-41 Onozawa M et al. Clinical parameters that predict histology of postchemotherapy retroperitoneal lymph node mass in testicular cancer. Int J Urol. 2004; 11: 535-41
9.
Zurück zum Zitat Li XD et al. Clinical outcome of postchemotherapy retroperitoneal lymph node dissection and predicting retroperitoneal histology in advanced nonseminomatous germ cell tumours of the testis. Zhonghua Wai Ke Za Zhi. 2017; 55: 603-7 Li XD et al. Clinical outcome of postchemotherapy retroperitoneal lymph node dissection and predicting retroperitoneal histology in advanced nonseminomatous germ cell tumours of the testis. Zhonghua Wai Ke Za Zhi. 2017; 55: 603-7
10.
Zurück zum Zitat Spiess PE et al. Viable malignant germ cell tumor in the postchemotherapy retroperitoneal lymph node dissection specimen: can it be predicted using clinical parameters? Cancer. 2006; 107: 1503-10 Spiess PE et al. Viable malignant germ cell tumor in the postchemotherapy retroperitoneal lymph node dissection specimen: can it be predicted using clinical parameters? Cancer. 2006; 107: 1503-10
11.
Zurück zum Zitat Vergouwe Y et al. Predicting retroperitoneal histology in postchemotherapy testicular germ cell cancer: a model update and multicentre validation with more than 1000 patients. Eur Urol. 2007; 51: 424-32 Vergouwe Y et al. Predicting retroperitoneal histology in postchemotherapy testicular germ cell cancer: a model update and multicentre validation with more than 1000 patients. Eur Urol. 2007; 51: 424-32
12.
Zurück zum Zitat Leao R et al. A New Model to Predict Benign Histology in Residual Retroperitoneal Masses After Chemotherapy in Nonseminoma. Eur Urol Focus. 2018; 4: 995-1001 Leao R et al. A New Model to Predict Benign Histology in Residual Retroperitoneal Masses After Chemotherapy in Nonseminoma. Eur Urol Focus. 2018; 4: 995-1001
13.
Zurück zum Zitat Steyerberg EW et al. Validity of predictions of residual retroperitoneal mass histology in nonseminomatous testicular cancer. J Clin Oncol. 1998; 16: 269-74 Steyerberg EW et al. Validity of predictions of residual retroperitoneal mass histology in nonseminomatous testicular cancer. J Clin Oncol. 1998; 16: 269-74
14.
Zurück zum Zitat Albers P et al. Prediction of necrosis after chemotherapy of advanced germ cell tumors: results of a prospective multicenter trial of the German Testicular Cancer Study Group. J Urol. 2004; 171: 1835-8 Albers P et al. Prediction of necrosis after chemotherapy of advanced germ cell tumors: results of a prospective multicenter trial of the German Testicular Cancer Study Group. J Urol. 2004; 171: 1835-8
15.
Zurück zum Zitat Paffenholz P et al. Independent validation of two models to predict necrosis/fibrosis in post chemotherapy residual retroperitoneal masses of patients with advanced testicular cancer Eur Urol Suppl. 2019; 18: 827 Paffenholz P et al. Independent validation of two models to predict necrosis/fibrosis in post chemotherapy residual retroperitoneal masses of patients with advanced testicular cancer Eur Urol Suppl. 2019; 18: 827
16.
Zurück zum Zitat Oechsle K et al. [18F]Fluorodeoxyglucose positron emission tomography in nonseminomatous germ cell tumors after chemotherapy: the German multicenter positron emission tomography study group. J Clin Oncol. 2008; 26: 5930-5 Oechsle K et al. [18F]Fluorodeoxyglucose positron emission tomography in nonseminomatous germ cell tumors after chemotherapy: the German multicenter positron emission tomography study group. J Clin Oncol. 2008; 26: 5930-5
17.
Zurück zum Zitat Lewin J et al. Applying Radiomics to Predict Pathology of Postchemotherapy Retroperitoneal Nodal Masses in Germ Cell Tumors. JCO Clin Cancer Inform. 2018; 2: 1-12 Lewin J et al. Applying Radiomics to Predict Pathology of Postchemotherapy Retroperitoneal Nodal Masses in Germ Cell Tumors. JCO Clin Cancer Inform. 2018; 2: 1-12
18.
Zurück zum Zitat Gillis AJ et al. High-throughput microRNAome analysis in human germ cell tumours. J Pathol. 2007; 213: 319-28 Gillis AJ et al. High-throughput microRNAome analysis in human germ cell tumours. J Pathol. 2007; 213: 319-28
19.
Zurück zum Zitat Dieckmann KP et al. Serum Levels of MicroRNA-371a-3p (M371 Test) as a New Biomarker of Testicular Germ Cell Tumors: Results of a Prospective Multicentric Study. J Clin Oncol. 2019; 37: 1412-23 Dieckmann KP et al. Serum Levels of MicroRNA-371a-3p (M371 Test) as a New Biomarker of Testicular Germ Cell Tumors: Results of a Prospective Multicentric Study. J Clin Oncol. 2019; 37: 1412-23
20.
Zurück zum Zitat Leao R et al. Serum miRNA Predicts Viable Disease after Chemotherapy in Patients with Testicular Nonseminoma Germ Cell Tumor. J Urol. 2018; 200: 126-35 Leao R et al. Serum miRNA Predicts Viable Disease after Chemotherapy in Patients with Testicular Nonseminoma Germ Cell Tumor. J Urol. 2018; 200: 126-35
21.
Zurück zum Zitat Shen H et al. Integrated Molecular Characterization of Testicular Germ Cell Tumors. Cell Rep. 2018; 23: 3392-406 Shen H et al. Integrated Molecular Characterization of Testicular Germ Cell Tumors. Cell Rep. 2018; 23: 3392-406
22.
Zurück zum Zitat Kremer L et al. The combination of microRNA-371a-3p and 375-5p can distinguish viable germ cell tumor and teratoma from necrosis in postchemotherapy retroperitoneal lymph node dissection specimens. Transl Androl Urol. 2021; 10: 1647-55 Kremer L et al. The combination of microRNA-371a-3p and 375-5p can distinguish viable germ cell tumor and teratoma from necrosis in postchemotherapy retroperitoneal lymph node dissection specimens. Transl Androl Urol. 2021; 10: 1647-55
23.
Zurück zum Zitat Nappi L et al. Integrated Expression of Circulating miR375 and miR371 to Identify Teratoma and Active Germ Cell Malignancy Components in Malignant Germ Cell Tumors. Eur Urol. 2021; 79: 16-9 Nappi L et al. Integrated Expression of Circulating miR375 and miR371 to Identify Teratoma and Active Germ Cell Malignancy Components in Malignant Germ Cell Tumors. Eur Urol. 2021; 79: 16-9
24.
Zurück zum Zitat Paffenholz P et al. External validation of 2 models to predict necrosis/fibrosis in postchemotherapy residual retroperitoneal masses of patients with advanced testicular cancer. Urol Oncol. 2019; 37: 809.e9-18 Paffenholz P et al. External validation of 2 models to predict necrosis/fibrosis in postchemotherapy residual retroperitoneal masses of patients with advanced testicular cancer. Urol Oncol. 2019; 37: 809.e9-18
25.
Zurück zum Zitat Baessler B et al. Radiomics allows for detection of benign and malignant histopathology in patients with metastatic testicular germ cell tumors prior to post-chemotherapy retroperitoneal lymph node dissection. Eur Radiol. 2020; 30: 2334-45 Baessler B et al. Radiomics allows for detection of benign and malignant histopathology in patients with metastatic testicular germ cell tumors prior to post-chemotherapy retroperitoneal lymph node dissection. Eur Radiol. 2020; 30: 2334-45
Metadaten
Titel
Residualtumoren beim metastasierten Hodentumor
Wie lassen sich maligne und benigne Befunde unterscheiden?
verfasst von
PD Dr. med. Tim Nestler
Prof. Dr. med. Dr. h. c. Axel Heidenreich
Publikationsdatum
07.03.2022
Verlag
Springer Medizin
Erschienen in
Uro-News / Ausgabe 3/2022
Print ISSN: 1432-9026
Elektronische ISSN: 2196-5676
DOI
https://doi.org/10.1007/s00092-022-4837-x

Weitere Artikel der Ausgabe 3/2022

Uro-News 3/2022 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.