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2017 | OriginalPaper | Buchkapitel

17. Diagnostik kardiovaskulärer Krankheiten

verfasst von : Prof. Dr. med. Evangelos Giannitsis, Prof. Dr. Ingolf Schimke, Prof. Dr. Peter B. Luppa, Prof. Dr. Dirk Peetz

Erschienen in: POCT - Patientennahe Labordiagnostik

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Der bevorzugte Biomarker in der Herzinfarktdiagnostik ist das quantitativ im Serum gemessene kardiale Troponin (cTn) wegen seiner Gewebespezifität. Bei Verwendung hochsensitiver cTn-Assays wird die Bestimmung weiterer Marker wie Myoglobin, CK-MB Masse, FABP nicht empfohlen, da diese Biomarker keinen diagnostischen Zusatznutzen bringen. Hochsensitive cTn-Assays werden bislang von zwei POCT-Benchtop-Geräten angeboten. Für die labormedizinische Begleitung der chronischen Herzinsuffizienz stehen heute mit dem BNP und dem NT-pro-BNP Marker zur Verfügung, deren Einsatz von Europäischen und Amerikanischen Fachgesellschaften für Screening und Diagnostik der Herzinsuffizienz empfohlen wird. POCT-Methoden zur Messung sind bereits entwickelt worden.
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Metadaten
Titel
Diagnostik kardiovaskulärer Krankheiten
verfasst von
Prof. Dr. med. Evangelos Giannitsis
Prof. Dr. Ingolf Schimke
Prof. Dr. Peter B. Luppa
Prof. Dr. Dirk Peetz
Copyright-Jahr
2017
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-54196-8_17

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