Pathophysiology
The pathologic mechanism of DRA is complex and involves many factors, including anatomical structure, muscle function, and physiological changes. While DRA is more common in women, especially during pregnancy and the postpartum period, men may also be affected. Studies have indicated that DRA may be associated with a decrease in core muscle strength, which can in turn lead to issues such as low back pain [
17]. From an anatomical perspective, hormonal changes during pregnancy are a crucial factor. Pregnancy-related hormonal fluctuations cause the connective tissues of the abdominal wall to relax, creating conditions that facilitate the development of DRA. A study of 171 pregnant women using ultrasound measurements found that as pregnancy progressed, the IRD at 37 weeks of gestation was significantly greater than at 12 weeks; at 6 weeks postpartum the IRD had decreased but remained higher than the 12-week measurement. Meanwhile, the rectus abdominis thickness and Young's modulus at 37 weeks were markedly reduced, and although they partially recovered by 6 weeks postpartum, they were still lower than at 12 weeks. These findings demonstrate that significant changes occur in the abdominal muscles and connective tissue during pregnancy [
10].
In men, the occurrence of DRA may be related to factors such as increased abdominal pressure, obesity, and improper exercise techniques. Obesity leads to accumulation of abdominal fat and elevated intra-abdominal pressure, which can promote the separation of the rectus abdominis. Additionally, certain high-intensity or inappropriate exercise routines might cause or exacerbate DRA [
18]. It is important that postoperative rehabilitation and exercise regimens be carefully managed to avoid further separation of the abdominal muscles.
Moreover, mechanical factors should not be overlooked. During pregnancy, progressive uterine enlargement imposes sustained pressure on the abdominal wall, resulting in gradual elongation and thinning of the rectus abdominis muscles. In certain cases, an anteriorly positioned fetus concentrates tensile forces on the linea alba rather than allowing uniform stress distribution across the abdominal wall. This localized and prolonged mechanical strain contributes significantly to the separation of the rectus muscles. Some studies also indicate that individual predispositions such as multiparity, a higher body mass index (BMI), and diabetes can increase the risk of DRA. For example, women who have had multiple pregnancies experience repeated abdominal wall stretching, raising the likelihood of DRA. Individuals with a high BMI accumulate excess abdominal fat, adding burden to the abdominal wall and potentially precipitating DRA. Diabetes may affect muscle metabolism and structure, thereby impairing the normal function of the rectus abdominis and increasing the incidence of DRA [
8].
Clinical evaluation criteria
Clinical evaluation is very important for accurately judging the separation of rectus abdominis and formulating reasonable treatment plan. Common evaluation methods include physical examination and the use of specific questionnaires. In physical examination, the presence of DRA is determined by measuring the IRD, for example, using digital nylon calipers at locations above, at, and below the umbilicus. Studies have shown that clinical examination correlates well with ultrasound measurements of rectus abdominis separation, making it a reliable method when imaging is not available [
26]. In one study, postpartum women were evaluated using a specific finger width distance as a criterion to determine the presence and severity of DRA [
15]. Physical examination can also help identify other issues associated with DRA, such as low back pain and stress urinary incontinence [
17,
27].
In addition, several questionnaires are employed to assess the impact of DRA on patients’ quality of life. For example, the International Consultation on ICIQ-FLUTS is used to evaluate urinary symptoms, and the SF-36 questionnaire is used to quantify health-related quality of life. In a study of 51 patients who underwent rectus separation and correction surgery, these questionnaires were evaluated before and after surgery, and the mean scores obtained by analyzing the questionnaires showed significant improvement in urinary symptoms and quality of life after surgery, suggesting that these questionnaires can assist in evaluating the efficacy of DRA treatment to some extent [
28]. In addition, it can also be combined with the symptoms of patients, such as co-existing low back pain or PFD, to comprehensively assess DRA’s impact and develop corresponding treatment strategies.
Comparison of diagnostic methods
Various diagnostic modalities for DRA have distinct advantages and limitations. Ultrasound is easy to perform, highly repeatable, and free of radiation, allowing real-time observation of the rectus abdominis. It is well-suited for dynamic assessment of DRA, for example, tracking changes in the IRD during various stages of pregnancy and postpartum [
1]. However, ultrasound results may be affected by operator experience and manipulation, and some fine structures may not be as clearly observed as MRI and CT.
CT can provide excellent anatomical detail and can clearly show the abdominal wall muscles, fascia structure, and IRD. It is also able to accurately and repeatably measure the width of the white line and the degree of rectus abdominis separation at multiple levels (supraumbilical, periumbilical, subumbilical). At the same time, the co-existing diseases such as abdominal wall hernia, muscle atrophy, fat infiltration or intra-abdominal lesions can be found. CT reconstruction technology allows for multi-plane and three-dimensional visualization that provides a comprehensive assessment of the integrity of the abdominal wall. But CT involves ionizing radiation, which mainly limits young patients, pregnant women, or those who need repeated tests. CT cannot assess muscle function or dynamic changes (e.g., during straining).
In terms of soft tissue contrast, MRI provides better soft tissue resolution than CT and ultrasound, and can show the rectus abdominis muscle, the white line, and the peripheral fascia in detail. Moreover, MRI uses magnetic fields instead of ionizing radiation, effectively avoids the risks associated with ionizing radiation, making it safer for younger patients, pregnant women, and patients with repeated tests. At the same time, advanced MRI techniques, such as cine-MRI, can assess abdominal wall movements, muscle contractions, or strain patterns to provide functional information. However, the cost is high, the scan time is long, and patients must meet certain physical requirements (e.g., no metal implants, ability to tolerate confinement in the scanner). These limitations make MRI unsuitable for some patients.
Furthermore, other diagnostic approaches like physical examination combined with patient questionnaires, though relatively simple, offer important insights into patient-reported symptoms and functional deficits. These methods complement imaging examinations, and together they can improve the accuracy of DRA diagnosis (Table
1).
Table 1
Comparison of diagnostic methods for DRA
Radiation Exposure | No | No | Yes | No |
Dynamic Assessment | Strong | Strong | Limited | Limited |
Quantitative Accuracy | Low | Moderate | High | High |
Soft Tissue Resolution | Poor | Moderate | Good | Excellent |
Operator Dependence | High | High | Low | Moderate |
Cost & Accessibility | Low | Low | Moderate to High | High |
Broad Patient Suitability | High | High | Limited (due to radiation) | Limited (due to contraindications) |
Advances in surgical treatment
For patients with more severe DRA, surgical intervention is often an important option. A variety of surgical techniques have been utilized to repair DRA. Various open repair techniques are available, including direct suture repair, rectus abdominis muscle plication, and mesh reinforcement. These procedures typically involve approximation of the anterior rectus sheath or placement of a prosthetic mesh to restore abdominal wall integrity. In contrast, mesh-based repair has demonstrated lower recurrence and complication rates, particularly in patients with a DRA width of ≥ 10 cm, leading to superior long-term outcomes [
41]. In patients with concurrent skin redundancy, subcutaneous fat accumulation, or pronounced aesthetic deformity, open repair is often combined with abdominoplasty. This approach allows for resection of excess cutaneous and subcutaneous tissues while simultaneously reinforcing the abdominal wall through rectus sheath plication or overlapping suture techniques. The goal is to achieve both functional restoration and aesthetic improvement [
28].
Minimally invasive surgery is also increasingly applied in the treatment of DRA. a completely endoscopic subcutaneous repair (as detailed later in Technical Advances) has shown feasibility in correcting DRA with concurrent midline hernias, yielding significant aesthetic improvements [
42]. Furthermore, robotic-assisted techniques have been introduced; for example, the robotic transabdominal retromuscular rectus diastasis (r-TARRD) repair offers a new minimally invasive option. In a series of 45 patients undergoing r-TARRD, the average operative time was 192 min and the average hospital stay was 4.2 days. At one month postoperatively, 1 patient (2.22%) had a mesh infection, and at one year 4 patients (8.88%) had a recurrence. These findings suggest that r-TARRD is generally safe and effective, though refinements and longer-term follow-up are still needed [
43] (Table
2).
Table 2
Comparison between r-TARRD and Traditional Open Plication for Rectus Diastasis Repair
Surgical Approach | Laparoscopic access with robotic assistance | Open midline incision |
Extent of Tissue Dissection | Confined to the retromuscular (posterior) space | Extensive subcutaneous flap elevation |
Mesh Use | Optional (commonly used in moderate-to-severe cases) | Generally not used |
Average Operative Time | 180–240 min | Approximately 135 min |
Length of Hospital Stay | 1–3 days (some suitable for outpatient surgery) | Same-day or overnight |
Postoperative Recovery | Faster, less pain, minimal scarring | More discomfort, slower recovery |
Aesthetic Outcome | Superior (small, concealed incisions) | Prominent scar, especially with concurrent abdominoplasty |
Recurrence Rate | Very low (especially with mesh use) | Relatively higher (10–20%) |
Postoperative Complications | Rare (notably low infection rates) | More common (e.g., seroma, hematoma) |
Patient Selection | Ideal for moderate-to-severe DRA, recurrent cases, poor tissue quality | Suitable for mild-to-moderate DRA, cost-sensitive patients |
Cost | High (robotic platform and materials) | Lower (no advanced equipment required) |
Moreover, repairing DRA (especially in conjunction with hernia repair) may reduce certain complications. For example, one study found that correcting rectus diastasis lowers the risk of postoperative abdominal wound dehiscence [
44]. Another study on achieving long-term stability by using absorbable sutures to repair DRA has been confirmed, indicating that this method can maintain the stability of the abdominal wall after surgery [
45]. Anterior compartment mobilisation (ACM), performed via a posterior dissection plane, has demonstrated favorable outcomes in the management of very severe DRA. The technique facilitates medial advancement of the rectus muscles and anterior rectus sheaths to restore midline integrity. In a cohort of 282 patients undergoing repair for large ventral or incisional hernias, ACM achieved complete fascial closure in all cases. At one-year follow-up, there were no recurrences or major complications, and only two patients (0.7%) experienced minor complications. These findings support the feasibility and effectiveness of ACM in treating complex midline defects, including severe DRA [
46].
In summary, surgical treatment plays a vital role in the management of severe DRA. However, patient selection for surgery should be cautious, as discussed later, given ongoing debates about indications.
Rehabilitation training programs
Rehabilitation is a crucial component of DRA management, focusing on strengthening the abdominal and pelvic floor muscles. Multiple studies have evaluated exercise-based programs. Studies have shown that standardized rehabilitation can significantly improve the condition of DRA in postpartum women and enhance their quality of life [
47]. For instance, in one study of 70 women with DRA at 6–12 months postpartum, the intervention group underwent a standardized 12-week exercise regimen (including head lift, abdominal curl, and oblique abdominal curl exercises, 5 days per week). Although this exercise program did not significantly change the IRD, it led to increases in rectus abdominis thickness (MD 0.7 mm, 95% CI 0.1 to 1.3) and muscle strength (MD 9 Nm, 95% CI 3 to 16), indicating that targeted abdominal exercises can enhance abdominal muscle strength and thickness [
31]. Another study investigated core stability training combined with transcutaneous electrical acupoint stimulation in postpartum women with DRA, and found that this combined approach significantly reduced the degree of DRA and also reduced waist circumference and improved quality of life [
11]. These findings highlight the particular importance of core muscle training in DRA rehabilitation.
At the same time, integrating pelvic floor muscle training into the rehabilitation program is also of great significance. Early implementation of low-intensity combined pelvic floor and abdominal muscle exercises has been shown to have positive effects on postpartum recovery. In a longitudinal study of 504 postpartum women divided into different exercise groups, those in a low-intensity exercise group experienced relief of pelvic floor pain and a modest improvement in DRA within the first year postpartum, suggesting that early low-intensity combined rehabilitation training is of important value for postpartum recovery [
32].
Additionally, emerging therapies such as electro-acupuncture combined with physical exercise have proven effective in improving DRA. In a randomized controlled trial, patients receiving electro-acupuncture therapy showed greater improvement in DRA compared to those performing exercise alone, and the beneficial effect remained significant at 26 weeks post-intervention [
37]. Pilates, which has become popular in recent years, has also been shown to have a positive impact on DRA in postpartum women. Studies indicate that Pilates training can effectively reduce the IRD, decrease waist circumference, and improve abdominal muscle endurance [
48].
In addition, The TOR (Training, Operation, and Rehabilitation) concept has emerged as a novel strategy for managing abdominal wall dysfunction and DRA. This multidisciplinary approach integrates preoperative symptom assessment, individualized core strengthening, tailored surgical repair, and structured postoperative rehabilitation. Preliminary evidence suggests that TOR may significantly improve physical function and quality of life in postpartum women [
49].
In summary, well-designed rehabilitation training programs are of great importance in the treatment of DRA. Such programs can improve the function of the rectus abdominis and enhance patients’ quality of life. Of note, rehabilitation protocols should be individualized according to each patient’s specific condition in order to achieve optimal outcomes.
Application of biomaterials
Biomaterials play an important role in the treatment of DRA, primarily by enhancing repair effectiveness and promoting tissue healing. Research indicates that biomaterials can promote wound healing by modulating cellular behavior and dynamically remodeling the extracellular matrix, thereby maximizing regenerative and reparative outcomes [
52].
Biologic meshes are used in abdominal wall reconstruction to provide both structural reinforcement and support for tissue integration. Clinical data suggest they may reduce postoperative complication rates in specific contexts [
13]. Their biodegradable properties enable gradual replacement by native tissue, facilitating repair of abdominal wall defects [
53]. Preliminary studies have reported that biologic meshes may enable early closure of contaminated or potentially contaminated defects, particularly when primary skin closure is not feasible, by promoting granulation tissue formation and secondary healing [
54]. However, these benefits remain subject to debate. A systematic review by Köckerling et al. assessed outcomes from multiple studies and found no consistent evidence supporting the superiority of biologic or biosynthetic meshes over synthetic alternatives in contaminated fields [
55]. Similarly, other reviews have emphasized the limited quantity and quality of existing data, which do not substantiate claims that biologic meshes are less susceptible to infection or associated with lower explantation rates [
56,
57].Further well-designed prospective studies are essential to clarify the role of biologic meshes in contaminated abdominal wall repair and to validate their purported advantages over synthetic materials.
Additionally, some absorbable materials have increasingly been used in DRA repair. In a study of 51 patients, absorbable sutures were used for rectus sheath plication, and postoperative ultrasound examination found no significant difference in IRD at long-term follow-up compared to traditional permanent sutures [
45]. This finding suggests that absorbable sutures appear to reliably maintain long-term abdominal wall stability, offering a new material option for DRA treatment (Table
3).
Table 3
Comparison of Biomaterial Types Used in the Surgical Treatment of DRA
Biologic Meshes | Abdominal wall reconstruction and closure of contaminated or potentially contaminated defects | Biodegradable, promotes tissue integration, may support healing in contaminated fields | Controversial efficacy in contaminated environments, higher cost, limited high-quality evidence |
Synthetic Meshes | Abdominal wall reinforcement, especially in clean surgical settings | Durable, widely available, lower cost | Higher risk of infection and foreign body reactions in contaminated fields |
Absorbable Sutures | Rectus sheath plication in DRA repair | Maintains long-term abdominal wall stability, avoids permanent implants | Limited long-term data, potential decrease in tensile strength over time |
In summary, the application of biomaterials in DRA treatment not only enhances repair outcomes but also promotes tissue healing, providing more possibilities for effective management of DRA. With ongoing advances in materials science, it is anticipated that new biomaterials will be developed to further improve DRA treatment outcomes.