Skip to main content

01.12.2018 | Original Article | Ausgabe 1/2018

Archives of Osteoporosis 1/2018

Diet and exercise changes following bone densitometry in the Patient Activation After DXA Result Notification (PAADRN) study

Archives of Osteoporosis > Ausgabe 1/2018
Douglas W. Roblin, Peter Cram, Yiyue Lou, Stephanie W. Edmonds, Sylvie F. Hall, Michael P. Jones, Kenneth G. Saag, Nicole C. Wright, Fredric D. Wolinsky, on behalf of the PAADRN Investigators
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s11657-017-0402-8) contains supplementary material, which is available to authorized users.



Calcium and vitamin D intake and exercise are suboptimal among older adults. Following bone densitometry, a letter communicating individualized fracture risk accompanied by an educational brochure improved participants’ lifestyle—but no more than existing communication strategies—over 52 weeks. Simple communication strategies are insufficient for achieving optimal levels of bone health behaviors.


The Patient Activation After DXA Result Notification (PAADRN) study was designed to evaluate whether a letter with individualized fracture risk and an educational brochure mailed to patients soon after their DXA might improve bone health behaviors (daily calcium intake, vitamin D supplementation, and weekly exercise sessions) compared to slower, less individualized communication characterizing usual care.


Participants ≥ 50 years were recruited, at three sites, following their DXA and randomized with 1:1 allocation to intervention and control (usual care only) groups. Data were collected at enrollment interview and by phone survey at 12 and 52 weeks thereafter. Intention-to-treat analyses were conducted on 7749 of the 20,397 eligible participants who enrolled. Changes in bone health behaviors were compared within and between study groups. Average treatment effects and heterogeneity of treatment effects were estimated with multivariable linear and logistic regression models.


In unadjusted analyses, calcium intake, vitamin D supplementation, and weekly exercise sessions increased significantly over 52 weeks within both the intervention and control groups (all p < 0.001). In unadjusted analyses and multivariable models, increases in each behavior did not significantly differ between the intervention and control groups. Intervention group participants with a > 20% 10-year fracture risk at enrollment did, however, have a significantly greater increase in calcium intake compared to other study participants (p = 0.031).


Bone health behaviors improved, on average, over 52 weeks among all participants following a DXA. Receipt of the PAADRN letter and educational brochure did not directly improve bone health behaviors compared to usual care.

Trial registration

The Patient Activation after DXA Result Notification (PAADRN) Study is registered at ClinicalTrials.Gov: NCT01507662, https://​clinicaltrials.​gov/​ct2/​show/​NCT01507662

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Jetzt e.Med zum Sonderpreis bestellen! 

Table S1 (DOCX 30 kb).
Table S2 (DOCX 28 kb).
Table S3 (DOCX 29 kb).
Table S4 (DOCX 32 kb).
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2018

Archives of Osteoporosis 1/2018 Zur Ausgabe


Neu im Fachgebiet Orthopädie und Unfallchirurgie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Orthopädie und Unfallchirurgie und bleiben Sie gut informiert – ganz bequem per eMail.