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Erschienen in: Sleep and Breathing 4/2021

06.01.2021 | Psychiatrics • Original Article

Differential relationship of two measures of sleepiness with the drives for sleep and wake

verfasst von: Vladimir B. Dorokhov, Dmitry S. Sveshnikov, Alexandra N. Puchkova, Anton I. Taranov, Dmitry S. Sakharov, Svetlana S. Gruzdeva, Olga N. Tkachenko, Gleb N. Arsen’ev, Natalya V. Ligun, Valeriy V. Dementienko, Zarina B. Bakaeva, Elena B. Yakunina, Yuri P. Starshinov, Vladimir I. Torshin, Olga G. Donskaya, Arcady A. Putilov

Erschienen in: Sleep and Breathing | Ausgabe 4/2021

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Abstract

Purpose

Since disagreement has been found between an objective sleep propensity measured by sleep onset latency (SOL) and subjective sleepiness assessment measured by the Epworth sleepiness scale (ESS) score, distinct underlying causes and consequences were suggested for these two sleepiness measures. We addressed the issue of validation of the ESS against objective sleepiness and sleep indexes by examining the hypothesis that these two sleepiness measures are disconnected due to their differential relationship with the antagonistic drives for sleep and wake.

Methods

The polysomnographic records of 50-min napping attempts were collected from 27 university students on three occasions. Scores on the first and second principal components of the electroencephalographic (EEG) spectrum were calculated to measure the sleep and wake drives, respectively. Self-assessments of subjective sleepiness and sleep were additionally collected in online survey of 633 students at the same university.

Results

An ESS score was disconnected with the polysomnographic and self-assessed SOL in the nap study and online survey, respectively. An ESS score but not SOL was significantly linked to the spectral EEG measure of the sleep drive, while SOL but not ESS showed a significant association with the spectral EEG measure of the opposing wake drive.

Conclusions

Each of two sleepiness measures was validated against objective indicators of the opposing sleep-wake regulating processes, but different underlying causes were identified for two distinct aspects of sleepiness. A stronger sleep drive and a weaker opposing drive for wake seem to contribute to a higher ESS score and to a shorter SOL, respectively.
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Metadaten
Titel
Differential relationship of two measures of sleepiness with the drives for sleep and wake
verfasst von
Vladimir B. Dorokhov
Dmitry S. Sveshnikov
Alexandra N. Puchkova
Anton I. Taranov
Dmitry S. Sakharov
Svetlana S. Gruzdeva
Olga N. Tkachenko
Gleb N. Arsen’ev
Natalya V. Ligun
Valeriy V. Dementienko
Zarina B. Bakaeva
Elena B. Yakunina
Yuri P. Starshinov
Vladimir I. Torshin
Olga G. Donskaya
Arcady A. Putilov
Publikationsdatum
06.01.2021
Verlag
Springer International Publishing
Erschienen in
Sleep and Breathing / Ausgabe 4/2021
Print ISSN: 1520-9512
Elektronische ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-020-02269-w

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