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Erschienen in:
03.09.2020 | Original Article
Differentiation malignant from benign parotid tumors in children with diffusion-weighted MR imaging
Erschienen in: Oral Radiology | Ausgabe 3/2021
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Purpose
To differentiate pediatric solid malignant from the benign parotid tumors with diffusion-weighted MR imaging (DWI).
Materials and methods
A retrospective study comprising 38 children with parotid tumors (21 boys and 17 girls aged from 2 months to 17 years) was conducted using (DWI) of the parotid gland. Apparent diffusion coefficient (ADC) maps were generated. The ADC value of the parotid tumors was calculated.
Results
The mean ADC value of malignant parotid tumors (1.08 ± 0.1, 1.04 ± 0.1 × 10−3mm2/s) was significantly lower [P = 0.001] than that of benign lesions (1.69 ± 0.2, 1.72 ± 0.3 × 10−3mm2/s). A threshold of ADC of 1.40, 1.33 × 10−3mm2/s was used for differentiating malignant parotid tumors from benign lesions and led to the best results of the area under the curve of 0.940, 0.929, accuracy of 86, 89%, sensitivity of 94, 94%, specificity of 80, 85%, negative predictive value of 94.1, 94.4%, and positive predictive value of 81, 85%. There was insignificant difference in ADC values of malignant lesions (P = 0.23, 0.30) as well as within benign lesions (P = 0.25, 0.08).
Conclusion
DWI is an innovative anticipating imaging technique that can be used in the differentiation of pediatric solid malignant parotid tumors from benign lesions.