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01.03.2013 | Case Report

Diffuse panbronchiolitis after humanized anti-CCR4 monoclonal antibody therapy for relapsed adult T-cell leukemia/lymphoma

verfasst von: Koji Kato, Toshihiro Miyamoto, Akihiko Numata, Takashi Nakaike, Hideyo Oka, Ayano Yurino, Takuro Kuriyama, Yasuo Mori, Satoshi Yamasaki, Tsuyoshi Muta, Katsuto Takenaka, Hiromi Iwasaki, Takanori Teshima, Koichi Akashi

Erschienen in: International Journal of Hematology | Ausgabe 3/2013

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Abstract

We present the case of a 62-year-old Japanese woman with relapsed adult T-cell leukemia/lymphoma (ATLL) who was treated with humanized anti-CCR4 monoclonal antibody (KW-0761). Although this antibody was highly effective against refractory ATLL, 6 months after the final KW-0761 infusion, the patient complained of hypoxia due to diffuse panbronchiolitis. Physicians should remain vigilant to the possibility of such previously unreported late-onset adverse effects associated with KW-0761 therapy.

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Titel: Diffuse panbronchiolitis after humanized anti-CCR4 monoclonal antibody therapy for relapsed adult T-cell leukemia/lymphoma
verfasst von: Koji Kato
Toshihiro Miyamoto
Akihiko Numata
Takashi Nakaike
Hideyo Oka
Ayano Yurino
Takuro Kuriyama
Yasuo Mori
Satoshi Yamasaki
Tsuyoshi Muta
Katsuto Takenaka
Hiromi Iwasaki
Takanori Teshima
Koichi Akashi
Publikationsdatum: 01.03.2013
Verlag: Springer Japan
Erschienen in: International Journal of Hematology / Ausgabe 3/2013
Print ISSN: 0925-5710
Elektronische ISSN: 1865-3774
DOI: https://doi.org/10.1007/s12185-013-1278-z

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18.04.2024 | Wirbelsäulenmetastase | Nachrichten

Springer Medizin

Diffuse panbronchiolitis after humanized anti-CCR4 monoclonal antibody therapy for relapsed adult T-cell leukemia/lymphoma

Abstract

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Abstract

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