Anzeige
Erschienen in:
11.10.2019 | Original Article
Direct Admission vs. Secondary Transfer to a Comprehensive Stroke Center for Thrombectomy
Retrospective Analysis of a Regional Stroke Registry with 2797 Patients
Erschienen in: Clinical Neuroradiology | Ausgabe 4/2020
Einloggen, um Zugang zu erhaltenAbstract
Background and Purpose
This study aimed at comparing short-term clinical outcome after thrombectomy in patients directly admitted (DA) to a comprehensive stroke center with patients secondarily transferred (ST) from a primary stroke center.
Methods
In a prospective regional stroke registry, all stroke patients with a premorbid modified Rankin scale (mRS) score 0–2 who were admitted within 24 h after stroke onset and treated with thrombectomy between 2014 and 2017 were retrospectively analyzed. Patients with DA and ST were compared regarding the proportion of good outcome (discharge mRS 0–2), median discharge mRS, mRS shift (difference between premorbid mRS and mRS on discharge) and occurrence of symptomatic intracranial hemorrhage.
Results
Out of 2797 patients, 1051 (37.6%) achieved good clinical outcome. In the DA group (n = 1657), proportion of good outcome was higher (DA 42.2% vs. ST 30.9%, P < 0.001) and median discharge mRS (DA 3 vs. ST 4, P < 0.001) and median mRS shift (DA 3 vs. ST 4, P < 0.001) were lower. The rate of symptomatic intracranial hemorrhage was similar in both groups (DA 9.3% vs. ST 7.5%, P = 0.101). Multivariate analysis revealed that direct admission was an independent predictor of good clinical outcome (adjusted odds ratio, OR 1.32, confidence interval, CI 1.09–1.60, P = 0.004).
Conclusion
These results confirm prior studies stating that DA to a comprehensive stroke center leads to better outcome compared to ST in stroke patients undergoing thrombectomy.