Introduction
Methods
Study population
CMR protocol
Visual assessment of splenic switch-off
Rest-stress T1-mapping analysis
Statistical analysis
Results
Controls | Coffee < 4Ha
| p value | |
---|---|---|---|
N = 124 | N = 22 | ||
Male, n (%) | 63 (51%) | 13 (59%) | |
Age, years | 65 ± 11 | 65 ± 10 | 0.730 |
Body weight, kg | 80 [67;88] | 80 [71;96] | 0.377 |
Resting heart rate, beats/min | 74 [67;83] | 67 [65;76] | 0.050 |
Stress heart rate, beats/min | 88 [77;100] | 84 [78;89] | 0.104 |
Rest systolic blood pressure, mm Hg | 143 [127;156] | 141 [121;159] | 0.590 |
Rest diastolic blood pressure, mm Hg | 82 [76;89] | 81 [75;88] | 0.747 |
Stress systolic blood pressure, mm Hg | 135 [123;152] | 135 [125;146] | 0.844 |
Stress diastolic blood pressure, mm Hg | 80 [73;85] | 78 [72;83] | 0.333 |
SSO and T1-mapping of the spleen
Controlsa
| Coffee intake < 4 Ha
| p-value | |
---|---|---|---|
N = 124 | N = 22 | ||
T1myocard rest, ms | 977 [956;994] | 963 [955;991] | 0.457 |
T1myocard stress, ms | 1015 [998;1045] | 924 [879;946] | < 0.001 |
Myocardial ΔT1, % | 4.0 [2.8;5.7] | − 5.2 [− 8.1;− 3.6] | < 0.001 |
T1spleen rest, ms | 1022 [994;1078] | 1028 [994;1067] | 0.943 |
T1spleen stress, ms | 987 [960;1031] | 993 [941;1021] | 0.520 |
Splenic ΔT1, % | − 4.0 [− 5.3;− 2.5] | − 3.7 [− 6.7;− 2.5] | 0.789 |
Splenic ΔT1, ms | − 40 [− 59;− 25] | − 38 [− 71;− 26] | 0.810 |
Splenic ΔT1 ≥ 30 ms, n (%) | 87 (70) | 15 (68) | 0.852 |
SSO, n (%) | 117 (94) | 21 (96) | 0.835 |