Erschienen in:
01.02.2020 | Review
Distinctive features of bovine alphaherpesvirus types 1 and 5 and the virus-host interactions that might influence clinical outcomes
verfasst von:
Maia Marin, Mercedes Burucúa, Daniel Rensetti, Juan José Rosales, Anselmo Odeón, Sandra Pérez
Erschienen in:
Archives of Virology
|
Ausgabe 2/2020
Einloggen, um Zugang zu erhalten
Abstract
Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alphaherpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic, they differ in their neuropathogenic potential. This review summarizes the findings on the specific mechanisms and pathways known to modulate the pathogenesis of BoHV-1 and BoHV-5, particularly in relation to respiratory and neurological syndromes, which characterize BoHV-1 and BoHV-5 infections, respectively.