Background
Methods
Data acquisition and patients’ characteristics
Characteristic | n (%) |
---|---|
Tumor stage | |
cT1c | 6 (18.8) |
cT2a | 1 (3.1) |
cT2b | 3 (9.4) |
cT2c | 4 (12.5) |
cT3a | 5 (15.6) |
cT3b | 3 (9.4) |
Tx | 6 (18.8) |
cN1 | 32 (100) |
cM0 | 30 (93.75) |
cM1a | 1 (3.1) |
cM1b | 0 |
D’Amico risk group | |
Low | 2 (6.3) |
Intermediate | 4 (12.5) |
High | 26 (81.25) |
Initial PSA level (ng/ml) | |
Mean | 32.78 |
Median | 21.71 |
Range | 5.1–198.0 |
PSA at the time of PET/CT (ng/ml) | |
Mean | 22.7 |
Median | 12.5 |
Range | 0.03–99.0 |
Gleason score | |
≤6 | 7 (21.88) |
7 (3 + 4) | 3 (9.4) |
7 (4 + 3) | 4 (12.5) |
8 | 1 (3.1) |
9 | 8 (25.0) |
missing | 9 (28.1) |
Age (years) | |
Mean | 69.2 |
Median | 71 |
Range | 51–80 |
Time from initial diagnosis until PET/CT (months) | |
Mean | 10.8 |
Median | 1 |
Range | 0–83 |
Characteristic | n (%) |
---|---|
Tumor stage | |
pT2a | 6 (6.9) |
pT2b | 4 (4.6) |
pT2c | 15 (17.2) |
pT3a | 20 (23) |
pT3b | 37 (42.5) |
pT4 | 1 (1.1) |
Tx | 4 (4.6) |
pN0 | 54 (62.1) |
pN1 | 30 (34.5) |
pM1a | 3 (3.4) |
R0 | 39 (44.8) |
R1 | 41 (47.1) |
Rx | 7 (8.0) |
Gleason score | |
≤6 | 10 (11.5) |
7 (3 + 4) | 18 (20.7) |
7 (4 + 3) | 16 (18.4) |
8 | 12 (13.8) |
9 | 21 (24.1) |
10 | 1 (1.1) |
missing | 9 (10.3) |
Initial PSA (ng/ml) | |
Mean | 28.7 |
Median | 10.35 |
Range | 1.56–392.00 |
Nadir (postoperative PSA) (ng/ml) | |
Mean | 1.85 |
Median | 0.23 |
Range | 0–32.00 |
PSA at the time of PET/CT (ng/ml) | |
Mean | 6.43 |
Median | 3.12 |
Range | 0.21–56.00 |
Age (years) | |
Mean | 62.4 |
Median | 63 |
Range | 41–82 |
Time from surgery until PET/CT (months) | |
Mean | 48.2 |
Median | 32.0 |
Range | 0–209 |
PET/CT imaging
Atlas of lymph node distribution
Results
Location and distribution of PET positive lymph nodes
Location | Region affected | Lymph nodes affected n; (%/all pathologic lymph nodes) | Geographical miss (n = regions) | Geographical miss n; (%/pathologic lymph nodes) |
---|---|---|---|---|
Internal pudendal nodes | 7 | 7 (2.4) | 0 | 0 |
Inferior rectal nodes | 0 | 0 | ||
Periprostatic lymphatic plexus | 1 | 1 (0.3) | 0 | 0 |
Seminal vesicle lymphatic plexus | 0 | 0 | ||
Perirectal lymphatic plexus | 10 | 11 (3.8) | 8 | 9 (81.8) |
Perivesical lymphatic plexus | 10 | 11 (3.8) | 7 | 7 (63.6) |
Sacral nodes | 3 | 6 (2.1) | 2 | 5 (83.3) |
Internal iliac nodes | 32 | 37 (13.0) | 0 | 0 |
External iliac nodes | 60 | 73 (25.4) | 7 | 7 (9.6) |
Superior rectal nodes | 2 | 2 (0.7) | 2 | 2 (100) |
Common iliac nodes | 52 | 70 (24.4) | 11 | 12 (17.1) |
Para-aortic nodes | 31 | 57 (19.9) | 31 | 57 (100) |
Inguinal nodes | 11 | 12 (4.2) | 11 | 12 (100) |
Total | 219 | 287 | 79 | 111 (38.7) |
Location | Region affected | Lymph nodes affected n; (%/all pathologic lymph nodes) | Geographical miss (n = regions) | Geographical miss n; (%/pathologic lymph nodes) |
---|---|---|---|---|
Internal pudendal nodes | 2 | 2 (2.6) | 0 | 0 |
Inferior rectal nodes | 0 | 0 | ||
Periprostatic lymphatic plexus | 1 | 1 (1.3) | 0 | 0 |
Seminal vesicle lymphatic plexus | 0 | 0 | ||
Perirectal lymphatic plexus | 3 | 4 (5.1) | 3 | 4 (100) |
Perivesical lymphatic plexus | 3 | 3 (3.8) | 3 | 3 (100) |
Sacral nodes | 0 | 0 | ||
Internal iliac nodes | 7 | 7 (8.9) | 0 | 0 |
External iliac nodes | 20 | 25 (32.1) | 4 | 4 (16.0) |
Superior rectal nodes | 0 | 0 | ||
Common iliac nodes | 12 | 18 (23.1) | 4 | 5 (27.8) |
Para-aortic nodes | 7 | 15 (19.2) | 7 | 15 (100) |
Inguinal nodes | 3 | 3 (3.9) | 3 | 3 (100) |
Total | 58 | 78 | 24 | 34 (43.6) |
Location | Region affected | Lymph nodes affected n; (%/all pathologic lymph nodes) | Geographical miss (n = regions) | Geographical miss n; (%/pathologic lymph nodes) |
---|---|---|---|---|
Internal pudendal nodes | 5 | 5 (2.4) | 0 | 0 |
Inferior rectal nodes | 0 | 0 | ||
Periprostatic lymphatic plexus | 0 | 0 | ||
Seminal vesicle lymphatic plexus | 0 | 0 | ||
Perirectal lymphatic plexus | 7 | 7 (3.3) | 5 | 5 (71.4) |
Perivesical lymphatic plexus | 7 | 8 (3.8) | 4 | 4 (50) |
Sacral nodes | 3 | 6 (2.9) | 2 | 5 (83.3) |
Internal iliac nodes | 25 | 30 (14.4) | 0 | 0 |
External iliac nodes | 40 | 48 (23.0) | 3 | 3 (6.3) |
Superior rectal nodes | 2 | 2 (1) | 2 | 2 (100) |
Common iliac nodes | 40 | 52 (24.9) | 7 | 7 (13.5) |
Para-aortic nodes | 24 | 42 (20.1) | 24 | 42 (100) |
Inguinal nodes | 8 | 9 (4.3) | 8 | 9 (100) |
Total | 161 | 209 | 55 | 77 (36.8) |