Skip to main content
Erschienen in: Tumor Biology 12/2016

08.10.2016 | Review

Diverse roles of miR-335 in development and progression of cancers

verfasst von: Long-ji Luo, Dan-dan Wang, Jing Wang, Fan Yang, Jin-hai Tang

Erschienen in: Tumor Biology | Ausgabe 12/2016

Einloggen, um Zugang zu erhalten

Abstract

MicroRNAs (miRNAs), a series of small noncoding RNAs that regulate gene expression at the post-transcriptional/translational level, are pivotal in cell differentiation, biological development, occurrence, and development of diseases, especially in cancers. Early studies have shown that miRNA-335 (miR-335) is widely dysregulated in human cancers and play critical roles in tumorigenesis and tumor progression. In this review, we aim to summarize the regulation of miR-335 expression mechanisms in cancers. We focus on the target genes regulated by miR-335 and its downstream signaling pathways involved in the biological effects of tumor growth, invasion, and metastasis both in vitro and in vivo, and analyze the relationships between miR-335 expression and the clinical characteristics of tumors as well as its effects on prognosis. The collected evidences support the potential use of miR-335 in prognosis and diagnosis as well as the therapeutic prospects of miR-335 in cancers.
Literatur
2.
Zurück zum Zitat He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004;5(7):522–31.PubMedCrossRef He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004;5(7):522–31.PubMedCrossRef
3.
Zurück zum Zitat Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet. 2010;11(9):597–610.PubMed Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet. 2010;11(9):597–610.PubMed
6.
Zurück zum Zitat Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120(1):15–20.PubMedCrossRef Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120(1):15–20.PubMedCrossRef
7.
Zurück zum Zitat Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell. 2003;115(7):787–98.PubMedCrossRef Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell. 2003;115(7):787–98.PubMedCrossRef
8.
Zurück zum Zitat Gunaratne PH, Creighton CJ, Watson M, Tennakoon JB. Large-scale integration of MicroRNA and gene expression data for identification of enriched microRNA-mRNA associations in biological systems. Methods Mol Biol. 2010;667:297–315.PubMedCrossRef Gunaratne PH, Creighton CJ, Watson M, Tennakoon JB. Large-scale integration of MicroRNA and gene expression data for identification of enriched microRNA-mRNA associations in biological systems. Methods Mol Biol. 2010;667:297–315.PubMedCrossRef
9.
Zurück zum Zitat Brennecke J, Hipfner DR, Stark A, Russell RB, Cohen SM. Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in drosophila. Cell. 2003;113(1):25–36.PubMedCrossRef Brennecke J, Hipfner DR, Stark A, Russell RB, Cohen SM. Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in drosophila. Cell. 2003;113(1):25–36.PubMedCrossRef
10.
Zurück zum Zitat Xu P, Vernooy SY, Guo M, Hay BA. The drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism. Curr Biol. 2003;13(9):790–5.PubMedCrossRef Xu P, Vernooy SY, Guo M, Hay BA. The drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism. Curr Biol. 2003;13(9):790–5.PubMedCrossRef
11.
Zurück zum Zitat Kawasaki H, Taira K. Hes1 is a target of microRNA-23 during retinoic-acid-induced neuronal differentiation of NT2 cells. Nature. 2003;423(6942):838–42.PubMedCrossRef Kawasaki H, Taira K. Hes1 is a target of microRNA-23 during retinoic-acid-induced neuronal differentiation of NT2 cells. Nature. 2003;423(6942):838–42.PubMedCrossRef
12.
Zurück zum Zitat Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature. 2000;403(6772):901–6.PubMedCrossRef Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature. 2000;403(6772):901–6.PubMedCrossRef
13.
Zurück zum Zitat Kong YW, Ferland-McCollough D, Jackson TJ, Bushell M. MicroRNAs in cancer management. Kong YW, Ferland-McCollough D, Jackson TJ, et al. microRNAs in cancer management. Lancet Oncol. 2012;13(6):e249–58.PubMedCrossRef Kong YW, Ferland-McCollough D, Jackson TJ, Bushell M. MicroRNAs in cancer management. Kong YW, Ferland-McCollough D, Jackson TJ, et al. microRNAs in cancer management. Lancet Oncol. 2012;13(6):e249–58.PubMedCrossRef
14.
Zurück zum Zitat Esquela-Kerscher A, Slack FJ. Oncomirs—microRNAs with a role in cancer. Nat Rev Cancer. 2006;6(4):259–69.PubMedCrossRef Esquela-Kerscher A, Slack FJ. Oncomirs—microRNAs with a role in cancer. Nat Rev Cancer. 2006;6(4):259–69.PubMedCrossRef
15.
Zurück zum Zitat Ventura A, Jacks T. MicroRNAs and cancer: short RNAs go a long way. Ventura a, jacks T, MicroRNAs and cancer: short RNAs go a long way. Cell. 2009;136(4):586–91.PubMedPubMedCentralCrossRef Ventura A, Jacks T. MicroRNAs and cancer: short RNAs go a long way. Ventura a, jacks T, MicroRNAs and cancer: short RNAs go a long way. Cell. 2009;136(4):586–91.PubMedPubMedCentralCrossRef
16.
17.
Zurück zum Zitat Fu Q, Liu X, Liu Y, Yang J, Lv G, Dong S. MicroRNA-335 and −543 suppress bone metastasis in prostate cancer via targeting endothelial nitric oxide synthase. Int J Mol Med. 2015;36(5):1417–25. doi:10.3892/ijmm.2015.2355.PubMed Fu Q, Liu X, Liu Y, Yang J, Lv G, Dong S. MicroRNA-335 and −543 suppress bone metastasis in prostate cancer via targeting endothelial nitric oxide synthase. Int J Mol Med. 2015;36(5):1417–25. doi:10.​3892/​ijmm.​2015.​2355.PubMed
20.
Zurück zum Zitat Dohi O, Yasui K, Gen Y, Takada H, Endo M, Tsuji K, et al. Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma. Int J Oncol. 2013;42(2):411–8. doi:10.3892/ijo.2012.1724.PubMed Dohi O, Yasui K, Gen Y, Takada H, Endo M, Tsuji K, et al. Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma. Int J Oncol. 2013;42(2):411–8. doi:10.​3892/​ijo.​2012.​1724.PubMed
21.
Zurück zum Zitat Heyn H, Engelmann M, Schreek S, Ahrens P, Lehmann U, Kreipe H, et al. MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development. Int J Cancer. 2011;129(12):2797–806. doi:10.1002/ijc.25962.PubMedCrossRef Heyn H, Engelmann M, Schreek S, Ahrens P, Lehmann U, Kreipe H, et al. MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development. Int J Cancer. 2011;129(12):2797–806. doi:10.​1002/​ijc.​25962.PubMedCrossRef
22.
Zurück zum Zitat Gao Y, Zeng F, JY W, Li HY, Fan JJ, Mai L, et al. MiR-335 inhibits migration of breast cancer cells through targeting oncoprotein c-met. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015;36(4):2875–83. doi:10.1007/s13277-014-2917-6.CrossRef Gao Y, Zeng F, JY W, Li HY, Fan JJ, Mai L, et al. MiR-335 inhibits migration of breast cancer cells through targeting oncoprotein c-met. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015;36(4):2875–83. doi:10.​1007/​s13277-014-2917-6.CrossRef
23.
Zurück zum Zitat Ronchetti D, Lionetti M, Mosca L, Agnelli L, Andronache A, Fabris S, et al. An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma. BMC Med Genet. 2008;1:37. doi:10.1186/1755-8794-1-37. Ronchetti D, Lionetti M, Mosca L, Agnelli L, Andronache A, Fabris S, et al. An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma. BMC Med Genet. 2008;1:37. doi:10.​1186/​1755-8794-1-37.
26.
Zurück zum Zitat Li Z, Li D, Zhang G, Xiong J, Jie Z, Cheng H, et al. Methylation-associated silencing of MicroRNA-335 contributes tumor cell invasion and migration by interacting with RASA1 in gastric cancer. Am J Cancer Res. 2014;4(6):648–62.PubMedPubMedCentral Li Z, Li D, Zhang G, Xiong J, Jie Z, Cheng H, et al. Methylation-associated silencing of MicroRNA-335 contributes tumor cell invasion and migration by interacting with RASA1 in gastric cancer. Am J Cancer Res. 2014;4(6):648–62.PubMedPubMedCentral
27.
Zurück zum Zitat Zhang S, Kim K, Jin UH, Pfent C, Cao H, Amendt B, et al. Aryl hydrocarbon receptor agonists induce microRNA-335 expression and inhibit lung metastasis of estrogen receptor negative breast cancer cells. Mol Cancer Ther. 2012;11(1):108–18. doi:10.1158/1535-7163.MCT-11-0548.PubMedCrossRef Zhang S, Kim K, Jin UH, Pfent C, Cao H, Amendt B, et al. Aryl hydrocarbon receptor agonists induce microRNA-335 expression and inhibit lung metastasis of estrogen receptor negative breast cancer cells. Mol Cancer Ther. 2012;11(1):108–18. doi:10.​1158/​1535-7163.​MCT-11-0548.PubMedCrossRef
28.
Zurück zum Zitat Heidary MF, Mahmoodzadeh Hosseini H, Mehdizadeh Aghdam E, Nourani MR, Ranjbar R, Mirnejad R, et al. Overexpression of metastatic related MicroRNAs, Mir-335 and Mir-10b, by staphylococcal enterotoxin B in the metastatic breast cancer cell line. Advanced pharmaceutical bulletin. 2015;5(2):255–9. doi:10.15171/apb.2015.035.PubMedPubMedCentralCrossRef Heidary MF, Mahmoodzadeh Hosseini H, Mehdizadeh Aghdam E, Nourani MR, Ranjbar R, Mirnejad R, et al. Overexpression of metastatic related MicroRNAs, Mir-335 and Mir-10b, by staphylococcal enterotoxin B in the metastatic breast cancer cell line. Advanced pharmaceutical bulletin. 2015;5(2):255–9. doi:10.​15171/​apb.​2015.​035.PubMedPubMedCentralCrossRef
29.
Zurück zum Zitat Lynch J, Fay J, Meehan M, Bryan K, Watters KM, Murphy DM, et al. MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-beta signalling pathway. Carcinogenesis. 2012;33(5):976–85. doi:10.1093/carcin/bgs114.PubMedPubMedCentralCrossRef Lynch J, Fay J, Meehan M, Bryan K, Watters KM, Murphy DM, et al. MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-beta signalling pathway. Carcinogenesis. 2012;33(5):976–85. doi:10.​1093/​carcin/​bgs114.PubMedPubMedCentralCrossRef
31.
Zurück zum Zitat Qiao J, Lee S, Paul P, Qiao L, Taylor CJ, Schlegel C, et al. Akt2 regulates metastatic potential in neuroblastoma. PLoS One. 2013;8(2). Qiao J, Lee S, Paul P, Qiao L, Taylor CJ, Schlegel C, et al. Akt2 regulates metastatic potential in neuroblastoma. PLoS One. 2013;8(2).
32.
Zurück zum Zitat Sankar N, Baluchamy S, Kadeppagari RK, Singhal G, Weitzman S, Thimmapaya B. p300 provides a corepressor function by cooperating with YY1 and HDAC3 to repress c-myc. Oncogene. 2008;27(43):5717–28.PubMedCrossRef Sankar N, Baluchamy S, Kadeppagari RK, Singhal G, Weitzman S, Thimmapaya B. p300 provides a corepressor function by cooperating with YY1 and HDAC3 to repress c-myc. Oncogene. 2008;27(43):5717–28.PubMedCrossRef
34.
Zurück zum Zitat Du L, Sun W, Zhang H, Chen D. BDE-209 inhibits pluripotent genes expression and induces apoptosis in human embryonic stem cells. Journal of applied toxicology: JAT. 2015. doi:10.1002/jat.3195. Du L, Sun W, Zhang H, Chen D. BDE-209 inhibits pluripotent genes expression and induces apoptosis in human embryonic stem cells. Journal of applied toxicology: JAT. 2015. doi:10.​1002/​jat.​3195.
35.
Zurück zum Zitat Shu M, Zhou Y, Zhu W, Zhang H, Wu S, Chen J, et al. MicroRNA 335 is required for differentiation of malignant glioma cells induced by activation of cAMP/protein kinase a pathway. Mol Pharmacol. 2012;81(3):292–8. doi:10.1124/mol.111.076166.PubMedCrossRef Shu M, Zhou Y, Zhu W, Zhang H, Wu S, Chen J, et al. MicroRNA 335 is required for differentiation of malignant glioma cells induced by activation of cAMP/protein kinase a pathway. Mol Pharmacol. 2012;81(3):292–8. doi:10.​1124/​mol.​111.​076166.PubMedCrossRef
38.
Zurück zum Zitat Woods A, Wang G, Beier F. RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis. J Biol Chem. 2005;280(12):11626–34.PubMedCrossRef Woods A, Wang G, Beier F. RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis. J Biol Chem. 2005;280(12):11626–34.PubMedCrossRef
39.
Zurück zum Zitat Lin X, Wu L, Zhang Z, Yang R, Guan Q, Hou X, et al. MiR-335-5p promotes chondrogenesis in mouse mesenchymal stem cells and is regulated through two positive feedback loops. J Bone Miner Res Off J Am Soc Bone Miner Res. 2014;29(7):1575–85. doi:10.1002/jbmr.2163.CrossRef Lin X, Wu L, Zhang Z, Yang R, Guan Q, Hou X, et al. MiR-335-5p promotes chondrogenesis in mouse mesenchymal stem cells and is regulated through two positive feedback loops. J Bone Miner Res Off J Am Soc Bone Miner Res. 2014;29(7):1575–85. doi:10.​1002/​jbmr.​2163.CrossRef
40.
Zurück zum Zitat Tome M, Lopez-Romero P, Albo C, Sepulveda JC, Fernandez-Gutierrez B, Dopazo A, et al. miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells. Cell Death Differ. 2011;18(6):985–95. doi:10.1038/cdd.2010.167.PubMedCrossRef Tome M, Lopez-Romero P, Albo C, Sepulveda JC, Fernandez-Gutierrez B, Dopazo A, et al. miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells. Cell Death Differ. 2011;18(6):985–95. doi:10.​1038/​cdd.​2010.​167.PubMedCrossRef
41.
Zurück zum Zitat Bates S, Phillips AC, Clark PA, Stott F, Peters G, Ludwig RL, et al. p14ARF links the tumour suppressors RB and p53. Nature. 1998;395(6698):124–5.PubMedCrossRef Bates S, Phillips AC, Clark PA, Stott F, Peters G, Ludwig RL, et al. p14ARF links the tumour suppressors RB and p53. Nature. 1998;395(6698):124–5.PubMedCrossRef
42.
Zurück zum Zitat Laurie NA, Donovan SL, Shih CS, Zhang J, Mills N, Fuller C, et al. Inactivation of the p53 pathway in retinoblastoma. Nature. 2006;444(7115):61–6.PubMedCrossRef Laurie NA, Donovan SL, Shih CS, Zhang J, Mills N, Fuller C, et al. Inactivation of the p53 pathway in retinoblastoma. Nature. 2006;444(7115):61–6.PubMedCrossRef
43.
Zurück zum Zitat Zhang J, Pickering CR, Holst CR, Gauthier ML, Tlsty TD. p16INK4a modulates p53 in primary human mammary epithelial cells. Cancer Res. 2006;66(21):10325–31.PubMedCrossRef Zhang J, Pickering CR, Holst CR, Gauthier ML, Tlsty TD. p16INK4a modulates p53 in primary human mammary epithelial cells. Cancer Res. 2006;66(21):10325–31.PubMedCrossRef
45.
Zurück zum Zitat Li X, Miyajima M, Jiang C, Arai H. Expression of TGF-betas and TGF-beta type II receptor in cerebrospinal fluid of patients with idiopathic normal pressure hydrocephalus. Neurosci Lett. 2007;413(2):141–4.PubMedCrossRef Li X, Miyajima M, Jiang C, Arai H. Expression of TGF-betas and TGF-beta type II receptor in cerebrospinal fluid of patients with idiopathic normal pressure hydrocephalus. Neurosci Lett. 2007;413(2):141–4.PubMedCrossRef
46.
Zurück zum Zitat Xu Y, Zhao F, Wang Z, Song Y, Luo Y, Zhang X, et al. MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1. Oncogene. 2012;31(11):1398–407. doi:10.1038/onc.2011.340.PubMedCrossRef Xu Y, Zhao F, Wang Z, Song Y, Luo Y, Zhang X, et al. MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1. Oncogene. 2012;31(11):1398–407. doi:10.​1038/​onc.​2011.​340.PubMedCrossRef
47.
Zurück zum Zitat Hiraga T, Myoui A, Hashimoto N, Sasaki A, Hata K, Morita Y, et al. Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases. Cancer Res. 2012;72(16):4238–49.PubMedPubMedCentralCrossRef Hiraga T, Myoui A, Hashimoto N, Sasaki A, Hata K, Morita Y, et al. Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases. Cancer Res. 2012;72(16):4238–49.PubMedPubMedCentralCrossRef
49.
Zurück zum Zitat Shu M, Zheng X, Wu S, Lu H, Leng T, Zhu W, et al. Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells. Mol Cancer. 2011;10(59):1476–4598. Shu M, Zheng X, Wu S, Lu H, Leng T, Zhu W, et al. Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells. Mol Cancer. 2011;10(59):1476–4598.
50.
Zurück zum Zitat Li H, Xie S, Liu M, Chen Z, Liu X, Wang L, et al. The clinical significance of downregulation of mir-124-3p, mir-146a-5p, mir-155-5p and mir-335-5p in gastric cancer tumorigenesis. Int J Oncol. 2014;45(1):197–208. doi:10.3892/ijo.2014.2415.PubMed Li H, Xie S, Liu M, Chen Z, Liu X, Wang L, et al. The clinical significance of downregulation of mir-124-3p, mir-146a-5p, mir-155-5p and mir-335-5p in gastric cancer tumorigenesis. Int J Oncol. 2014;45(1):197–208. doi:10.​3892/​ijo.​2014.​2415.PubMed
51.
Zurück zum Zitat Erturk E, Cecener G, Egeli U, Tunca B, Tezcan G, Gokgoz S, et al. Expression status of let-7a and miR-335 among breast tumors in patients with and without germ-line BRCA mutations. Mol Cell Biochem. 2014;395(1–2):77–88. doi:10.1007/s11010-014-2113-4.PubMedCrossRef Erturk E, Cecener G, Egeli U, Tunca B, Tezcan G, Gokgoz S, et al. Expression status of let-7a and miR-335 among breast tumors in patients with and without germ-line BRCA mutations. Mol Cell Biochem. 2014;395(1–2):77–88. doi:10.​1007/​s11010-014-2113-4.PubMedCrossRef
52.
Zurück zum Zitat Yan Z, Xiong Y, Xu W, Gao J, Cheng Y, Wang Z, et al. Identification of hsa-miR-335 as a prognostic signature in gastric cancer. PLoS One. 2012;7(7). Yan Z, Xiong Y, Xu W, Gao J, Cheng Y, Wang Z, et al. Identification of hsa-miR-335 as a prognostic signature in gastric cancer. PLoS One. 2012;7(7).
53.
Zurück zum Zitat Olson P, Lu J, Zhang H, Shai A, Chun MG, Wang Y, et al. MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev. 2009;23(18):2152–65.PubMedPubMedCentralCrossRef Olson P, Lu J, Zhang H, Shai A, Chun MG, Wang Y, et al. MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev. 2009;23(18):2152–65.PubMedPubMedCentralCrossRef
54.
Zurück zum Zitat Yang W, Lee DY, Ben-David Y. The roles of microRNAs in tumorigenesis and angiogenesis. Int J Physiol Pathophysiol Pharmacol. 2011;3(2):140–55.PubMed Yang W, Lee DY, Ben-David Y. The roles of microRNAs in tumorigenesis and angiogenesis. Int J Physiol Pathophysiol Pharmacol. 2011;3(2):140–55.PubMed
55.
Zurück zum Zitat Polytarchou C, Iliopoulos D, Struhl K. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci U S A. 2012;109(36):14470–5.PubMedPubMedCentralCrossRef Polytarchou C, Iliopoulos D, Struhl K. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci U S A. 2012;109(36):14470–5.PubMedPubMedCentralCrossRef
56.
Zurück zum Zitat Cheng Q, Cao H, Chen Z, Ma Z, Wan X, Peng R, et al. PAX6, a novel target of miR-335, inhibits cell proliferation and invasion in glioma cells. Mol Med Rep. 2014;10(1):399–404. doi:10.3892/mmr.2014.2150.PubMed Cheng Q, Cao H, Chen Z, Ma Z, Wan X, Peng R, et al. PAX6, a novel target of miR-335, inhibits cell proliferation and invasion in glioma cells. Mol Med Rep. 2014;10(1):399–404. doi:10.​3892/​mmr.​2014.​2150.PubMed
57.
58.
Zurück zum Zitat Yang B, Huang J, Liu H, Guo W, Li G. miR-335 directly, while miR-34a indirectly modulate survivin expression and regulate growth, apoptosis, and invasion of gastric cancer cells. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015. doi:10.1007/s13277-015-3951-8. Yang B, Huang J, Liu H, Guo W, Li G. miR-335 directly, while miR-34a indirectly modulate survivin expression and regulate growth, apoptosis, and invasion of gastric cancer cells. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015. doi:10.​1007/​s13277-015-3951-8.
59.
Zurück zum Zitat Liu H, Li W, Chen C, Pei Y, Long X. MiR-335 acts as a potential tumor suppressor miRNA via downregulating ROCK1 expression in hepatocellular carcinoma. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015;36(8):6313–9. doi:10.1007/s13277-015-3317-2.CrossRef Liu H, Li W, Chen C, Pei Y, Long X. MiR-335 acts as a potential tumor suppressor miRNA via downregulating ROCK1 expression in hepatocellular carcinoma. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015;36(8):6313–9. doi:10.​1007/​s13277-015-3317-2.CrossRef
60.
Zurück zum Zitat Wang H, Li M, Zhang R, Wang Y, Zang W, Ma Y, et al. Effect of miR-335 upregulation on the apoptosis and invasion of lung cancer cell A549 and H1299. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2013;34(5):3101–9. doi:10.1007/s13277-013-0878-9.CrossRef Wang H, Li M, Zhang R, Wang Y, Zang W, Ma Y, et al. Effect of miR-335 upregulation on the apoptosis and invasion of lung cancer cell A549 and H1299. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2013;34(5):3101–9. doi:10.​1007/​s13277-013-0878-9.CrossRef
61.
Zurück zum Zitat Wang K, Chen X, Zhan Y, Jiang W, Liu X, Wang X, et al. miR-335 inhibits the proliferation and invasion of clear cell renal cell carcinoma cells through direct suppression of BCL-W. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015;36(9):6875–82. doi:10.1007/s13277-015-3382-6.CrossRef Wang K, Chen X, Zhan Y, Jiang W, Liu X, Wang X, et al. miR-335 inhibits the proliferation and invasion of clear cell renal cell carcinoma cells through direct suppression of BCL-W. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015;36(9):6875–82. doi:10.​1007/​s13277-015-3382-6.CrossRef
63.
Zurück zum Zitat Xiong SW, Lin TX, KW X, Dong W, Ling XH, Jiang FN, et al. MicroRNA-335 acts as a candidate tumor suppressor in prostate cancer. Pathol Oncol Res. 2013;19(3):529–37.PubMedCrossRef Xiong SW, Lin TX, KW X, Dong W, Ling XH, Jiang FN, et al. MicroRNA-335 acts as a candidate tumor suppressor in prostate cancer. Pathol Oncol Res. 2013;19(3):529–37.PubMedCrossRef
64.
Zurück zum Zitat Gao L, Yang Y, Xu H, Liu R, Li D, Hong H, et al. MiR-335 functions as a tumor suppressor in pancreatic cancer by targeting OCT4. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014;35(8):8309–18. doi:10.1007/s13277-014-2092-9.CrossRef Gao L, Yang Y, Xu H, Liu R, Li D, Hong H, et al. MiR-335 functions as a tumor suppressor in pancreatic cancer by targeting OCT4. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014;35(8):8309–18. doi:10.​1007/​s13277-014-2092-9.CrossRef
65.
67.
Zurück zum Zitat Li G, MicroRNA PY. Signatures in total peripheral blood of gallbladder cancer patients. Tumour biology: the journal of the international society for. Oncodevelopmental Biology and Medicine. 2015;36(9):6985–90. doi:10.1007/s13277-015-3412-4.CrossRef Li G, MicroRNA PY. Signatures in total peripheral blood of gallbladder cancer patients. Tumour biology: the journal of the international society for. Oncodevelopmental Biology and Medicine. 2015;36(9):6985–90. doi:10.​1007/​s13277-015-3412-4.CrossRef
68.
Zurück zum Zitat Berx G, Raspé E, Christofori G, Thiery JP, Sleeman JP. Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Berx G, Raspé E, Christofori G, et al. pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin Exp Metastasis. 2007;24(8):587–97.PubMedCrossRef Berx G, Raspé E, Christofori G, Thiery JP, Sleeman JP. Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Berx G, Raspé E, Christofori G, et al. pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin Exp Metastasis. 2007;24(8):587–97.PubMedCrossRef
69.
Zurück zum Zitat Nguyen DX, Bos PD, Massagué J. Metastasis: from dissemination to organ-specific colonization. Nguyen DX, Bos PD, Massagué J, metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer. 2009;9(4):274–84.PubMedCrossRef Nguyen DX, Bos PD, Massagué J. Metastasis: from dissemination to organ-specific colonization. Nguyen DX, Bos PD, Massagué J, metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer. 2009;9(4):274–84.PubMedCrossRef
70.
Zurück zum Zitat Spaderna S, Schmalhofer O, Hlubek F, Jung A, Kirchner T, Brabletz T. Epithelial-mesenchymal and mesenchymal-epithelial transitions during cancer progression. Spaderna S, Schmalhofer O, Hlubek F, et al. epithelial-mesenchymal and mesenchymal-epithelial transitions during cancer progression. Verh Dtsch Ges Pathol. 2007:9121–8. Spaderna S, Schmalhofer O, Hlubek F, Jung A, Kirchner T, Brabletz T. Epithelial-mesenchymal and mesenchymal-epithelial transitions during cancer progression. Spaderna S, Schmalhofer O, Hlubek F, et al. epithelial-mesenchymal and mesenchymal-epithelial transitions during cancer progression. Verh Dtsch Ges Pathol. 2007:9121–8.
71.
Zurück zum Zitat Varki A, Varki NM, Borsig L. Molecular basis of metastasis. Varki a, Varki NM, Borsig L, molecular basis of metastasis. N Engl J Med. 2009;360(16):1678–9 .author reply 1679-80PubMedCrossRef Varki A, Varki NM, Borsig L. Molecular basis of metastasis. Varki a, Varki NM, Borsig L, molecular basis of metastasis. N Engl J Med. 2009;360(16):1678–9 .author reply 1679-80PubMedCrossRef
72.
Zurück zum Zitat Bae IH, Park MJ, Yoon SH, Kang SW, Lee SS, Choi KM, et al. Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1. Cancer Res. 2006;66(10):4991–5.PubMedCrossRef Bae IH, Park MJ, Yoon SH, Kang SW, Lee SS, Choi KM, et al. Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1. Cancer Res. 2006;66(10):4991–5.PubMedCrossRef
74.
Zurück zum Zitat Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Thiery JP, Acloque H, Huang RY, et al. epithelial-mesenchymal transitions in development and disease. Cell. 2009;139(5):871–90.PubMedCrossRef Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Thiery JP, Acloque H, Huang RY, et al. epithelial-mesenchymal transitions in development and disease. Cell. 2009;139(5):871–90.PubMedCrossRef
75.
Zurück zum Zitat Comijn J, Berx G, Vermassen P, Verschueren K, van Grunsven L, Bruyneel E, et al. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol Cell. 2001;7(6):1267–78.PubMedCrossRef Comijn J, Berx G, Vermassen P, Verschueren K, van Grunsven L, Bruyneel E, et al. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol Cell. 2001;7(6):1267–78.PubMedCrossRef
76.
Zurück zum Zitat Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer. 2007;7(6):415–28.PubMedCrossRef Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer. 2007;7(6):415–28.PubMedCrossRef
77.
Zurück zum Zitat Vandewalle C, Comijn J, De Craene B, Vermassen P, Bruyneel E, Andersen H, et al. SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions. Nucleic Acids Res. 2005;33(20):6566–78.PubMedPubMedCentralCrossRef Vandewalle C, Comijn J, De Craene B, Vermassen P, Bruyneel E, Andersen H, et al. SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions. Nucleic Acids Res. 2005;33(20):6566–78.PubMedPubMedCentralCrossRef
79.
Zurück zum Zitat Tocque B, Delumeau I, Parker F, Maurier F, Multon MC, Schweighoffer F. Ras-GTPase activating protein (GAP): a putative effector for Ras. Cell Signal. 1997;9(2):153–8.PubMedCrossRef Tocque B, Delumeau I, Parker F, Maurier F, Multon MC, Schweighoffer F. Ras-GTPase activating protein (GAP): a putative effector for Ras. Cell Signal. 1997;9(2):153–8.PubMedCrossRef
80.
Zurück zum Zitat Lu Y, Yang H, Yuan L, Liu G, Zhang C, Hong M, et al. Overexpression of miR-335 confers cell proliferation and tumour growth to colorectal carcinoma cells. Mol Cell Biochem. 2015;412(1–2):235–45. doi:10.1007/s11010-015-2630-9.PubMed Lu Y, Yang H, Yuan L, Liu G, Zhang C, Hong M, et al. Overexpression of miR-335 confers cell proliferation and tumour growth to colorectal carcinoma cells. Mol Cell Biochem. 2015;412(1–2):235–45. doi:10.​1007/​s11010-015-2630-9.PubMed
81.
Zurück zum Zitat Kessenbrock K, Plaks V, Werb Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Kessenbrock K, Plaks V, Werb Z, matrix metalloproteinases: regulators of the tumor microenvironment. Cell. 2010;141(1):52–67.PubMedPubMedCentralCrossRef Kessenbrock K, Plaks V, Werb Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Kessenbrock K, Plaks V, Werb Z, matrix metalloproteinases: regulators of the tumor microenvironment. Cell. 2010;141(1):52–67.PubMedPubMedCentralCrossRef
82.
Zurück zum Zitat Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, et al. Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011;138(2):303–15.PubMedPubMedCentralCrossRef Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, et al. Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011;138(2):303–15.PubMedPubMedCentralCrossRef
84.
Zurück zum Zitat Gingras D, Beliveau R. Emerging concepts in the regulation of membrane-type 1 matrix metalloproteinase activity. Biochim Biophys Acta. 2010;1:142–50.CrossRef Gingras D, Beliveau R. Emerging concepts in the regulation of membrane-type 1 matrix metalloproteinase activity. Biochim Biophys Acta. 2010;1:142–50.CrossRef
85.
Zurück zum Zitat D’Alessio S, Ferrari G, Cinnante K, Scheerer W, Galloway AC, Roses DF, et al. Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism. J Biol Chem. 2008;283(1):87–99.PubMedCrossRef D’Alessio S, Ferrari G, Cinnante K, Scheerer W, Galloway AC, Roses DF, et al. Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism. J Biol Chem. 2008;283(1):87–99.PubMedCrossRef
86.
Zurück zum Zitat Lin X, Wang Z, Zhang R, Feng W. High serum microRNA-335 level predicts aggressive tumor progression and unfavorable prognosis in pediatric acute myeloid leukemia. Clinical & translational oncology: official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2015;17(5):358–64. doi:10.1007/s12094-014-1237-z.CrossRef Lin X, Wang Z, Zhang R, Feng W. High serum microRNA-335 level predicts aggressive tumor progression and unfavorable prognosis in pediatric acute myeloid leukemia. Clinical & translational oncology: official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2015;17(5):358–64. doi:10.​1007/​s12094-014-1237-z.CrossRef
87.
Zurück zum Zitat Bao B, Ali S, Ahmad A, Li Y, Banerjee S, Kong D, et al. Differentially expressed miRNAs in cancer-stem-like cells: markers for tumor cell aggressiveness of pancreatic cancer. Stem Cells Dev. 2014;23(16):1947–58. doi:10.1089/scd.2013.0551.PubMedCrossRef Bao B, Ali S, Ahmad A, Li Y, Banerjee S, Kong D, et al. Differentially expressed miRNAs in cancer-stem-like cells: markers for tumor cell aggressiveness of pancreatic cancer. Stem Cells Dev. 2014;23(16):1947–58. doi:10.​1089/​scd.​2013.​0551.PubMedCrossRef
88.
Zurück zum Zitat Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature. 2005;435(7043):834–8.PubMedCrossRef Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature. 2005;435(7043):834–8.PubMedCrossRef
89.
Zurück zum Zitat Yang R, Dick M, Marme F, Schneeweiss A, Langheinz A, Hemminki K, et al. Genetic variants within miR-126 and miR-335 are not associated with breast cancer risk. Breast Cancer Res Treat. 2011;127(2):549–54. doi:10.1007/s10549-010-1244-x.PubMedCrossRef Yang R, Dick M, Marme F, Schneeweiss A, Langheinz A, Hemminki K, et al. Genetic variants within miR-126 and miR-335 are not associated with breast cancer risk. Breast Cancer Res Treat. 2011;127(2):549–54. doi:10.​1007/​s10549-010-1244-x.PubMedCrossRef
92.
Zurück zum Zitat Vickers MM, Bar J, Gorn-Hondermann I, Yarom N, Daneshmand M, Hanson JE, et al. Stage-dependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease. Clinical & experimental metastasis. 2012;29(2):123–32. doi:10.1007/s10585-011-9435-3.CrossRef Vickers MM, Bar J, Gorn-Hondermann I, Yarom N, Daneshmand M, Hanson JE, et al. Stage-dependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease. Clinical & experimental metastasis. 2012;29(2):123–32. doi:10.​1007/​s10585-011-9435-3.CrossRef
93.
Zurück zum Zitat Cui L, Hu Y, Bai B, Zhang S. Serum miR-335 level is associated with the treatment response to trans-arterial chemoembolization and prognosis in patients with hepatocellular carcinoma. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology. 2015;37(1):276–83. doi:10.1159/000430352.CrossRef Cui L, Hu Y, Bai B, Zhang S. Serum miR-335 level is associated with the treatment response to trans-arterial chemoembolization and prognosis in patients with hepatocellular carcinoma. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology. 2015;37(1):276–83. doi:10.​1159/​000430352.CrossRef
94.
Zurück zum Zitat Slattery ML, Herrick JS, Mullany LE, Valeri N, Stevens J, Caan BJ, et al. An evaluation and replication of miRNAs with disease stage and colorectal cancer-specific mortality. International journal of cancer Journal international du cancer. 2015;137(2):428–38. doi:10.1002/ijc.29384.PubMedCrossRef Slattery ML, Herrick JS, Mullany LE, Valeri N, Stevens J, Caan BJ, et al. An evaluation and replication of miRNAs with disease stage and colorectal cancer-specific mortality. International journal of cancer Journal international du cancer. 2015;137(2):428–38. doi:10.​1002/​ijc.​29384.PubMedCrossRef
95.
97.
Zurück zum Zitat Chabre O, Libe R, Assie G, Barreau O, Bertherat J, Bertagna X, et al. Serum miR-483-5p and miR-195 are predictive of recurrence risk in adrenocortical cancer patients. Endocrine-related cancer. 2013;20(4):579–94. doi:10.1530/ERC-13-0051.PubMed Chabre O, Libe R, Assie G, Barreau O, Bertherat J, Bertagna X, et al. Serum miR-483-5p and miR-195 are predictive of recurrence risk in adrenocortical cancer patients. Endocrine-related cancer. 2013;20(4):579–94. doi:10.​1530/​ERC-13-0051.PubMed
101.
Zurück zum Zitat Zhang BJ, Gong HY, Zheng F, Liu DJ, Liu HX. Up-regulation of miR-335 predicts a favorable prognosis in esophageal squamous cell carcinoma. Zhang BJ, gong HY, Zheng F, et al. up-regulation of miR-335 predicts a favorable prognosis in esophageal squamous cell carcinoma. Int J Clin Exp Pathol. 2014;7(9):6213–8.PubMedPubMedCentral Zhang BJ, Gong HY, Zheng F, Liu DJ, Liu HX. Up-regulation of miR-335 predicts a favorable prognosis in esophageal squamous cell carcinoma. Zhang BJ, gong HY, Zheng F, et al. up-regulation of miR-335 predicts a favorable prognosis in esophageal squamous cell carcinoma. Int J Clin Exp Pathol. 2014;7(9):6213–8.PubMedPubMedCentral
103.
Zurück zum Zitat Wang C, Jiang T. MicroRNA-335 represents an independent prognostic marker in cervical cancer. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015;36(8):5825–30. doi:10.1007/s13277-015-3252-2.CrossRef Wang C, Jiang T. MicroRNA-335 represents an independent prognostic marker in cervical cancer. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015;36(8):5825–30. doi:10.​1007/​s13277-015-3252-2.CrossRef
Metadaten
Titel
Diverse roles of miR-335 in development and progression of cancers
verfasst von
Long-ji Luo
Dan-dan Wang
Jing Wang
Fan Yang
Jin-hai Tang
Publikationsdatum
08.10.2016
Verlag
Springer Netherlands
Erschienen in
Tumor Biology / Ausgabe 12/2016
Print ISSN: 1010-4283
Elektronische ISSN: 1423-0380
DOI
https://doi.org/10.1007/s13277-016-5385-3

Weitere Artikel der Ausgabe 12/2016

Tumor Biology 12/2016 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.