Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Typ-2-Diabetes und Adipositas Klimawandel und Gesundheit Neues aus dem Markt Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende Patientenratgeber
Erweiterte Suche
Anmelden
nach oben
Supportive Care in Cancer
Erschienen in:

22.10.2016 | Review Article

Do-not-resuscitate orders in cancer patients: a review of literature

verfasst von: Aart Osinski, Gerard Vreugdenhil, Jan de Koning, Johannes G. van der Hoeven

Erschienen in: Supportive Care in Cancer | Ausgabe 2/2017

Einloggen, um Zugang zu erhalten

Abstract

Discussing do-not-resuscitate (DNR) orders is part of daily hospital practice in oncology departments. Several medical factors and patient characteristics are associated with issuing DNR orders in cancer patients. DNR orders are often placed late in the disease process. This may be a cause for disagreements between doctors and between doctors and patients and may cause for unnecessary treatments and admissions. In addition, DNR orders on itself may influence the rest of the medical treatment for patients. We present recommendations for discussing DNR orders and medical futility in practice through shared decision-making. Prospective studies are needed to investigate in which a patient’s cardiopulmonary resuscitation (CPR) is futile and whether or not DNR orders influence the medical care of patients.
Literatur
1.
Ebell MH, Doukas DJ, Smith MA (1991) The do-not-resuscitate order: a comparison of physician and patient preferences and decision-making. Am J Med 91(3):255–260CrossRefPubMed
2.
Ebell MH (1994) Practical guidelines for do-not-resuscitate orders. Am Fam Physician 50(6):1293–1299 1303-1294PubMed
3.
Hakim RB, Teno JM, Harrell FE Jr, Knaus WA, Wenger N, Phillips RS, Layde P, Califf R, Connors AF Jr, Lynn J (1996) Factors associated with do-not-resuscitate orders: patients’ preferences, prognoses, and physicians’ judgments. SUPPORT InvestigatorsStudy to understand prognoses and preferences for outcomes and risks of treatment. Ann Intern Med 125(4):284–293CrossRefPubMed
4.
5.
6.
7.
Hwang JP, Patlan J, de Achaval S, Escalante CP (2010) Survival in cancer patients after out-of-hospital cardiac arrest. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer 18(1):51–55. doi:10.​1007/​s00520-009-0629-z CrossRef
8.
Myrianthefs P, Batistaki C, Baltopoulos G (2010) Cardiopulmonary resuscitation in end-stage cancer patients. J BUON: Off J Balkan Union Oncol 15(1):25–28
9.
10.
Kjorstad OJ, Haugen DF (2013) Cardiopulmonary resuscitation in palliative care cancer patients. Tidsskrift for den Norske laegeforening: tidsskrift for praktisk medicin, ny raekke 133(4):417–421. doi:10.​4045/​tidsskr.​12.​0378 CrossRef
11.
12.
Varon J, Walsh GL, Marik PE, Fromm RE (1998) Should a cancer patient be resuscitated following an in-hospital cardiac arrest? Resuscitation 36(3):165–168CrossRefPubMed
13.
14.
Ewer MS, Kish SK, Martin CG, Price KJ, Feeley TW (2001) Characteristics of cardiac arrest in cancer patients as a predictor of survival after cardiopulmonary resuscitation. Cancer 92(7):1905–1912CrossRefPubMed
15.
Vitelli CE, Cooper K, Rogatko A, Brennan MF (1991) Cardiopulmonary resuscitation and the patient with cancer. J Clin Oncol Off J Am Soc Clin Oncol 9(1):111–115
16.
Hinkka H, Kosunen E, Metsanoja R, Lammi UK, Kellokumpu-Lehtinen P (2001) To resuscitate or not: a dilemma in terminal cancer care. Resuscitation 49(3):289–297CrossRefPubMed
17.
18.
19.
Chevaux F, Gagliano M, Waeber G, Marques-Vidal P, Schwab M (2015) Patients’ characteristics associated with the decision of “do not attempt cardiopulmonary resuscitation” order in a Swiss hospital. Eur J Intern Med 26(5):311–316. doi:10.​1016/​j.​ejim.​2015.​04.​003 CrossRefPubMed
20.
Parsons HA, de la Cruz MJ, Zhukovsky DS, Hui D, Delgado-Guay MO, Akitoye AE, El Osta B, Palmer L, Palla SL, Bruera E (2010) Characteristics of patients who refuse do-not-resuscitate orders upon admission to an acute palliative care unit in a comprehensive cancer center. Cancer 116(12):3061–3070. doi:10.​1002/​cncr.​25045 CrossRefPubMed
21.
22.
Keenan CH, Kish SK (2000) The influence of do-not-resuscitate orders on care provided for patients in the surgical intensive care unit of a cancer center. Crit Care Nurs Clin North Am 12(3):385–390PubMed
23.
Azad AA, Siow SF, Tafreshi A, Moran J, Franco M (2014) Discharge patterns, survival outcomes, and changes in clinical management of hospitalized adult patients with cancer with a do-not-resuscitate order. J Palliat Med 17(7):776–781. doi:10.​1089/​jpm.​2013.​0554 CrossRefPubMed
24.
Hermans HEGM, Buijsen MAJM (2010) Tweede, geheel herziene druk. Recht & gezondheidszorg. Maarssen: Elsevier Gezondheidszorg. Reed Business, Amsterdam
25.
26.
Rose JH, O’Toole EE, Dawson NV, Lawrence R, Gurley D, Thomas C, Hamel MB, Cohen HJ (2004) Perspectives, preferences, care practices, and outcomes among older and middle-aged patients with late-stage cancer. J Clin Oncol: Off J Am Soc Clin Oncol 22(24):4907–4917. doi:10.​1200/​JCO.​2004.​06.​050 CrossRef
27.
Covinsky KE, Fuller JD, Yaffe K, Johnston CB, Hamel MB, Lynn J, Teno JM, Phillips RS (2000) Communication and decision-making in seriously ill patients: findings of the SUPPORT project. The study to understand prognoses and preferences for outcomes and risks of treatments. J Am Geriatr Soc 48(5 Suppl):S187–S193CrossRefPubMed
28.
Wen KY, Lin YC, Cheng JF, Chou PC, Wei CH, Chen YF, Sun JL (2013) Insights into Chinese perspectives on do-not-resuscitate (DNR) orders from an examination of DNR order form completeness for cancer patients. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer 21(9):2593–2598. doi:10.​1007/​s00520-013-1827-2 CrossRef
29.
30.
Stein RA, Sharpe L, Bell ML, Boyle FM, Dunn SM, Clarke SJ (2013) Randomized controlled trial of a structured intervention to facilitate end-of-life decision making in patients with advanced cancer. J Clin Oncol Off J Am Soc Clin Oncol 31(27):3403–3410. doi:10.​1200/​JCO.​2011.​40.​8872 CrossRef
31.
Oh DY, Kim JH, Kim DW, Im SA, Kim TY, Heo DS, Bang YJ, Kim NK (2006) CPR or DNR? End-of-life decision in Korean cancer patients: a single center’s experience. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer 14(2):103–108. doi:10.​1007/​s00520-005-0885-5 CrossRef
32.
Mori M, Ellison D, Ashikaga T, McVeigh U, Ramsay A, Ades S (2013) In-advance end-of-life discussions and the quality of inpatient end-of-life care: a pilot study in bereaved primary caregivers of advanced cancer patients. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer 21(2):629–636. doi:10.​1007/​s00520-012-1581-x CrossRef
33.
Wright AA, Zhang B, Ray A, Mack JW, Trice E, Balboni T, Mitchell SL, Jackson VA, Block SD, Maciejewski PK, Prigerson HG (2008) Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment. JAMA 300(14):1665–1673. doi:10.​1001/​jama.​300.​14.​1665 CrossRefPubMedPubMedCentral
34.
Caissie A, Kevork N, Hannon B, Le LW, Zimmermann C (2014) Timing of code status documentation and end-of-life outcomes in patients admitted to an oncology ward. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer 22(2):375–381. doi:10.​1007/​s00520-013-1983-4 CrossRef
35.
von Gunten CF (2001) Discussing do-not-resuscitate status. J Clin Oncol Off J Am Soc Clin Oncol 19(5):1576–1581
36.
Saltbaek L, Michelsen HM, Nelausen KM, Gut R, Nielsen DL (2013) Old age and poor prognosis increase the likelihood of disagreement between cancer patients and their oncologists on the indication for resuscitation attempt. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer 21(12):3363–3370. doi:10.​1007/​s00520-013-1916-2 CrossRef
37.
Metadaten
Titel
Do-not-resuscitate orders in cancer patients: a review of literature
verfasst von
Aart Osinski
Gerard Vreugdenhil
Jan de Koning
Johannes G. van der Hoeven
Publikationsdatum
22.10.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 2/2017
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-016-3459-9

Weitere Artikel der Ausgabe 2/2017

Quality of life trajectories after diagnosis of gynecologic cancer: a theoretically based approach

  • Original Article

Burden of Chemotherapy-Induced Febrile Neutropenia Hospitalizations in US Clinical Practice, by Use and Patterns of Prophylaxis with Colony-Stimulating Factor

  • Original Article

Premedication with intravenous magnesium has a protective effect against cisplatin-induced nephrotoxicity

  • Original Article

Haematopoietic stem cell transplantation survivorship and quality of life: is it a small world after all?

  • Original Article

Feasibility of baseline neurocognitive assessment using Cogstate during the first month of therapy for childhood leukemia

  • Original Article

A qualitative exploration of oncology nurses’ family assessment practices in Denmark and Australia

  • Original Article

Neu im Fachgebiet Onkologie

Nierenzellkarzinom: Kein Nachteil durch subkutan appliziertes Nivolumab

Die subkutane Applikation von Nivolumab ist nach Daten einer Phase-3-Studie ähnlich gut wirksam wie die intravenöse: Die Pharmakokinetik ist vergleichbar, die objektive Response war in der Studie sogar leicht besser als in der Gruppe mit Infusionen.

Vorteile für Androgenentzug plus Androgenrezeptorblockade

Für Männer mit metastasiertem hormonsensitivem Prostata-Ca. (mHSPC), die keine Hormonchemotherapie wollen oder vertragen, ist der Androgenentzug plus Darolutamid eine Alternative: Das Progressionsrisiko wird im Vergleich zum alleinigen Androgenentzug fast halbiert.

CDK4/6-Inhibitoren bei Brustkrebs in die Zweitlinie aufschieben?

Ergebnisse einer Phase-III-Studie sprechen dafür, dass die Behandlung mit CDK4/6-Inhibitoren bei fortgeschrittenem HR-positivem, HER2-negativem Brustkrebs auch auf die Zweitlinie verschoben werden könnte, ohne die onkologischen Ergebnisse zu kompromittieren.

Cannabisextrakt verbessert Antiemese bei Chemotherapie

Sprechen Krebskranke auf die übliche Antiemese während einer Chemotherapie nicht ausreichend an, lohnt sich möglicherweise eine Behandlung mit Cannabisextrakt. In einer Phase-2/3-Studie ließ sich die antiemetische Response mit einem solchen Extrakt erheblich verbessern.

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen
Bildnachweise