Background
Methods
Results
Author | Joint | Comparators |
---|---|---|
Garcia-Rey 2008 [20] | Hip | Ultrahigh molecular weight polyethylene liner THR vs. highly cross-linked polyethylene liner THR |
Glyn-Jones 2008a [21] | Hip | Highly cross-linked polyethylene liner THR vs. ultrahigh molecular weight polyethylene liner THR |
Glyn-Jones 2008b [22] | Hip | Highly cross-linked polyethylene liner THR vs. ultrahigh molecular weight polyethylene liner THR |
Hamadouche 2008 [23] | Hip | Polished femoral stem THR vs. matte femoral stem THR |
Lachiewicz 2008 [24] | Hip | Polished femoral stem THR vs. pre-coated femoral stem THR |
Macaulay 2008 [25] | Hip | Hemiarthroplasty vs. THR |
Meneghini 2008 [26] | Hip | Two incision minimally invasive THR vs. mini-posterior approach THR vs. mini-anterolateral approach THR |
Mouzopoulos 2008 [27] | Hip | Hemiarthroplasty vs. THR vs. internal fixation |
Pagnano 2008 [28] | Hip | Mini-incision THR vs. two incision THR |
Pitto 2008 [29] | Hip | Polyethylene liner THR ceramic liner THR |
Barrett 2013 [30] | Hip | Direct anterior approach THR vs. posterolateral approach THR |
Bjorgul 2013 [31] | Hip | Metal-on-metal bearing THR vs. metal-on-polyethylene bearing THR vs. ceramic-on-polyethylene bearing THR |
Cadossi 2013 [32] | Hip | Hemiarthroplasty vs. polycarbonateurethane acetabular component THR |
Desmarchelier 2013 [33] | Hip | Metal-on-metal bearing THR vs. ceramic-on-ceramic bearing THR |
Greidanus 2013 [34] | Hip | Minimally invasive anterolateral approach THR vs. minimally invasive direct lateral approach THR vs. minimally invasive posterolateral approach THR |
Hedbeck 2013 [35] | Hip | Cemented hemiarthroplasty vs. internal fixation |
Inngul 2013 [36] | Hip | Unipolar hemiarthroplasty vs. bipolar hemiarthroplasty |
Kim 2013 [37] | Hip | Alumina-on-alumina ceramic bearing THR vs. alumina on highly cross-linked polyethylene bearing THR |
Landgraeber 2013 [38] | Hip | Minimally invasive THR vs. conventional THR |
Munzinger 2013 [39] | Hip | Titanium plasma-sprayed cup THR vs. titanium plasma-sprayed cup with additional hydroxyapatite coating THR |
Naudie 2013 [40] | Hip | Sintered bead porous surface shell THR vs. titanium anatomic porous surface THR |
Penny 2013 [41] | Hip | Standard THR vs. large head THR vs. resurfacing hip replacement |
Smolders 2013 [42] | Hip | Resurfacing hip replacement vs. THR |
Stiehler 2013 [43] | Hip | Navigated hip resurfacing vs. conventional hip resurfacing |
Venditolli 2013 [44] | Hip | Alumina on alumina vs. metal-on-polyethylene THR |
Vidovic 2013 [45] | Hip | Cemented hemiarthroplasty vs. cementless hemiarthroplasty |
Zagra 2013 [46] | Hip | 28 vs 36 vs. 42 mm bearing THR |
Breugem 2008 [47] | Knee | Fixed bearing TKR vs. mobile bearing TKR |
Chaudhary 2008 [48] | Knee | Posterior cruciate stabilising TKR vs. posterior cruciate-retaining TKR |
Dutton 2008 [49] | Knee | Computer-assisted minimally invasive TKR vs. conventional TKR |
Findlay 2008 [50] | Knee | Cemented TKR vs. uncemented TKR |
Hall 2008 [51] | Knee | Single radius of curvature femoral component TKR vs. multi-radius of curvature femoral component TKR |
Han 2008 [52] | Knee | Minimally invasive TKR vs. conventional TKR |
Hansson 2008 [53] | Knee | HA-coated TKR vs. Not HA-coated TKR |
Harato 2008 [54] | Knee | Posterior cruciate-retaining TKR vs. Posterior cruciate substituting TKR |
Karachalios 2008 [55] | Knee | Mini-mid vastus approach TKR standard approach TKR |
Ladermann 2008 [56] | Knee | Fixed bearing TKR vs. mobile bearing TKR |
Lionberger 2008 [57] | Knee | Electromagnetic navigation TKR vs. infrared navigation TKR |
Lozano 2008 [58] | Knee | Extramedullary tibial guide TKR vs. intramedullary tibial guide TKR |
Luring 2008 [59] | Knee | Navigated TKR vs. minimally invasive TKR vs. conventional TKR |
Lutzner 2008 [60] | Knee | Navigated TKR vs. conventional TKR |
Nutton 2008 [61] | Knee | Standard Nexgen TKR vs. high flexion Nexgen TKR |
Oberst 2008 [62] | Knee | Navigated TKR vs. conventional TKR |
Smith 2008 [63] | Knee | Patellar resurfacing TKR vs. no patellar resurfacing TKR |
Therbo 2008 [64] | Knee | HA coated tibial component TKR vs. no HA on tibial component TKR |
Wylde 2008 [65] | Knee | Fixed bearing TKR vs. mobile bearing TKR |
Aggarwal 2013 [66] | Knee | Fixed bearing TKR vs. mobile bearing TKR |
Breeman 2013 [67] | Knee | Mobile bearing TKR vs. fixed bearing TKR |
Chareancholvanich 2013 [68] | Knee | Patient-specific cutting guide TKR vs. conventional instrumentation TKR |
Dennis 2013 [69] | Knee | High flexion TKR vs. standard device TKR |
Fischer 2013 [70] | Knee | High flexion TKR vs. standard device TKR |
Hamilton DF 2013a [71] | Knee | Triathlon TKR vs. Kinemax TKR |
Hamilton DF 2013b [72] | Knee | Triathlon TKR vs. Kinemax TKR |
Hamilton WG 2013 [73] | Knee | Patient-specific instrumentation TKR vs. traditional instrumentation TKR |
Jarvis 2013 [74] | Knee | Standard parapatellar approach TKR vs. mini-parapatellar approach TKR |
Joseph 2013 [75] | Knee | Computer navigation TKR vs. no computer navigation TKR |
Jung 2013 [76] | Knee | Intramedullary alignment TKR vs. extra-medullary alignment TKR |
Nieuwenhuijse 2013 [77] | Knee | LPS-flex mobile TKR vs. LPS-flex-fixed TKR vs. LPS-fixed TKR vs. LPS mobile TKR |
Nishizawa 2013 [78] | Knee | Cruciate-retaining TKR vs. posterior stabilised TKR |
Pandit 2013 [79] | Knee | Cemented unicompartmental knee replacement vs. cementless unicompartmental knee replacement |
Radetzki 2013 [80] | Knee | High-flex NexGen LPS flex mobile bearing TKR vs. NexGen LPS TKR |
Roh 2013 [81] | Knee | Patient-specific instruments TKR vs. conventional instruments TKR |
Song 2013 [82] | Knee | Robotic-assisted TKR vs. conventional TKR instruments |
Umrani 2013 [83] | Knee | Patellar eversion TKR vs. no patellar eversion TKR |
Wegrzyn 2013 [84] | Knee | Mini-subvastus approach TKR vs. medial parapatellar approach TKR |
Yim 2013 [85] | Knee | Robot-assisted classical alignment TKR vs. robot-assisted anatomical alignment TKR |
Fialka 2008 [86] | Shoulder | Has shoulder hemiarthroplasty vs. epoca shoulder hemiarthroplasty |
Soliman 2013 [87] | Shoulder | Hemiarthroplasty and tenodesis of the long head of the biceps vs. hemiarthroplasty without tenodesis of the long head of the biceps |
Lapner 2013 [88] | Shoulder | Tuberosity osteotomy shoulder replacement vs. subscapularis peel shoulder replacement |
Hansen 2013 [89] | Hand | Cemented vs. uncemented cups in total trapeziometacarpal joint prostheses |
Composite joint-specific outcome tool | Proportion of eligible trials reporting n (%) | Constituent outcomes measured |
---|---|---|
Merle D’Aubigné and Postel Score (MDPS) | 3/27 (11) | Pain, function, ROM |
Oxford Hip Score (OHS) | 2/27 (7) | Pain, function |
Harris Hip Score (HHS) | 15/27 (56) | Pain, function, ROM |
Hip disability and Osteoarthritis outcomes score (HOOS) | 1/27 (4) | Pain, function, hip-related quality of life |
Hospital for Special Surgery (HSS) Knee Score | 4/39 (10) | Pain, function, ROM, knee stability, knee alignment (not using radiographs) |
Knee Society Clinical Rating System (KSS) | 16/39 (41) | Pain, function, ROM, knee stability, knee alignment (not using radiographs) |
Knee injury and Osteoarthritis Outcome Score (KOOS) | 3/39 (8) | Pain, function, knee-related quality of life |
Oxford Knee Score (OKS) | 6/39 (15) | Pain, function |
Western Ontario and McMaster Universities Arthritis Index (WOMAC) | 13/66 (20) | Pain, function, stiffness |
Western Ontario Osteoarthritis of the Shoulder (WOOS) | 1/3 (33) | Pain, function, shoulder-related quality of life |
American Shoulder and Elbow Surgeons (ASES) | 1/3 (33) | Pain, function, activity levels |
Constant Score | 1/3 (33) | Pain, strength, activity levels, ROM |
Disabilities of the Arm, Shoulder and Hand (DASH) Score | 1/4 (25) | Pain, function, strength, stiffness, hand-related quality of life |
Hip replacement trial outcome domains
Authors | Pathophysiological | Life impact | Death | All 3 core areas reported | Resource use/economic impacta
| ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pain | Stiffness | ROM | AE | Blood loss | RSA | RMAL | Satisfaction | Hip QoL | General QoL | Function | Activity levels | Mortality | LoI | Surgery time | LoS | Reop/readmit | Revision rate | ||
Garcia-Rey 2008 [20] | √ | √ | √ | √ | |||||||||||||||
Glyn-Jones 2008a [21] | √ | √ | √ | √ | |||||||||||||||
Glyn-Jones 2008b [22] | √ | √ | |||||||||||||||||
Hamadouche 2008 [23] | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||
Lachiewicz 2008 [24] | √ | √ | √ | √ | √ | √ | |||||||||||||
Macaulay 2008 [25] | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||
Meneghini 2008 [26] | √ | √ | |||||||||||||||||
Mouzopoulos 2008 [27] | √ | √ | √ | √ | √ | ||||||||||||||
Pagnano 2008 [28] | √ | √ | √ | √ | |||||||||||||||
Pitto 2008 [29] | √ | √ | √ | √ | |||||||||||||||
Barrett 2013 [30] | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||
Bjorgul 2013 [31] | √ | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||||
Cadossi 2013 [32] | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||
Desmarchelier 2013 [33] | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||
Greidanus 2013 [34] | √ | √ | √ | √ | √ | √ | √ | ||||||||||||
Hedbeck 2013 [35] | √ | √ | √ | √ | √ | √ | |||||||||||||
Inngul 2013 [36] | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||
Kim 2013 [37] | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||
Landgraeber 2013 [38] | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||
Munzinger 2013 [39] | √ | ||||||||||||||||||
Naudie 2013 [40] | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||
Penny 2013 [41] | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||
Smolders 2013 [42] | √ | √ | |||||||||||||||||
Stiehler 2013 [43] | √ | √ | √ | √ | √ | √ | |||||||||||||
Venditolli 2013 [44] | √ | √ | √ | ||||||||||||||||
Vidovic 2013 [45] | √ | √ | √ | √ | √ | √ | √ | ||||||||||||
Zagra 2013 [46] | √ | √ | √ |
Knee replacement trial outcome domains
Authors | Pathophysiological | Life impact | Death | All 3 core areas reported | Resource use/economic impacta
| |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pain | Stiffness | Knee stability | Knee alignment (clinical) | ROM | AE | Blood loss | RSA | RMAL | Satis | Knee QoL | General QoL | Function | Activity levels | Mortality | LoI | Surgery time | No. trays | LoS | Reop/readmit | Cost per patient | ||
Breugem 2008 [47] | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||||||
Chaudhary 2008 [48] | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||||
Dutton 2008 [49] | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||||
Findlay 2008 [50] | √ | √ | √ | √ | √ | √ | √ | |||||||||||||||
Hall 2008 [51] | √ | √ | √ | √ | √ | |||||||||||||||||
Han 2008 [52] | √ | √ | √ | √ | √ | √ | ||||||||||||||||
Hansson 2008 [53] | √ | √ | √ | √ | √ | |||||||||||||||||
Harato 2008 [54] | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||
Karachalios 2008 [55] | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||||
Ladermann 2008 [56] | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||||
Lionberger 2008 [57] | √ | |||||||||||||||||||||
Lozano 2008 [58] | √ | √ | ||||||||||||||||||||
Luring 2008 [59] | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||
Lutzner 2008 [60] | √ | √ | √ | |||||||||||||||||||
Nutton 2008 [61] | √ | √ | √ | √ | √ | √ | √ | |||||||||||||||
Oberst 2008 [62] | √ | |||||||||||||||||||||
Smith 2008 [63] | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||||||||
Therbo 2008 [64] | √ | √ | √ | √ | √ | √ | ||||||||||||||||
Wylde 2008 [65] | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||||||||
Aggarwal 2013 [66] | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||||||
Breeman 2013 [67] | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||||||||
Chareancholvanich 2013 [68] | √ | √ | √ | √ | √ | √ | ||||||||||||||||
Dennis 2013 [69] | √ | √ | √ | √ | √ | √ | ||||||||||||||||
Fischer 2013 [70] | √ | √ | √ | √ | √ | √ | ||||||||||||||||
Hamilton DF 2013a [71] | √ | |||||||||||||||||||||
Hamilton DF 2013b [72] | √ | √ | √ | √ | ||||||||||||||||||
Hamilton WG 2013 [73] | √ | √ | √ | |||||||||||||||||||
Jarvis 2013 [74] | √ | |||||||||||||||||||||
Joseph 2013 [75] | √ | √ | ||||||||||||||||||||
Jung 2013 [76] | √ | |||||||||||||||||||||
Nieuwenhuijse 2013 [77] | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||||
Nishizawa 2013 [78] | √ | |||||||||||||||||||||
Pandit 2013 [79] | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||||
Radetzki 2013 [80] | √ | √ | √ | √ | √ | √ | √ | √ | ||||||||||||||
Roh 2013 [81] | √ | |||||||||||||||||||||
Song 2013 [82] | √ | √ | √ | √ | √ | √ | √ | √ | √ | |||||||||||||
Umrani 2013 [83] | √ | √ | √ | √ | √ | √ | ||||||||||||||||
Wergrzyn 2013 [84] | √ | √ | √ | √ | √ | |||||||||||||||||
Yim 2013 [85] | √ | √ | √ | √ | √ | √ | √ |