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Erschienen in: International Urogynecology Journal 4/2010

01.04.2010 | Original Article

Do women with overactive bladder have realistic expectations for therapy?

verfasst von: Arasee Renganathan, Dudley Robinson, Linda Cardozo, Sushma Srikrishna, Rufus Cartwright

Erschienen in: International Urogynecology Journal | Ausgabe 4/2010

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Abstract

Introduction and hypothesis

This study aims to determine what women with overactive bladder (OAB) perceive as ‘cure’, assesses treatment acceptability and adverse events. It also determines impact on quality of life (QoL) and correlates it with expectations from therapy.

Methods

In 153 women with predominant OAB symptoms, QoL and expectations regarding ‘cure’ were assessed using KHQ and a novel questionnaire. Analyses were performed using Pearson’s correlation and ANOVA.

Results

Conservative measures and lifestyle modifications were acceptable whilst urge incontinence, coital incontinence, constant pad and medication usage were unpopular. Overall, 65% expected to stop leaking altogether once treated. Older women were less prepared to accept side effects such as constipation (p = 0.03) and dry mouth (p = 0.012). ANOVA showed significant difference between mean QoL scores for women with different expectations of cure (p = 0.049).

Conclusions

Majority of women have realistic expectations regarding treatment and are willing to tolerate minor symptoms. Regular antimuscarinics remain unpopular and may explain low persistence.
Literatur
1.
Zurück zum Zitat Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2002) Standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the international continence society. Am J Obstet Gynecol 187(1):116–126CrossRefPubMed Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2002) Standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the international continence society. Am J Obstet Gynecol 187(1):116–126CrossRefPubMed
2.
Zurück zum Zitat Irwin DE, Milsom I, Kopp Z, Abrams P, Cardozo L (2006) Impact of overactive bladder symptoms on employment, social interactions and emotional well-being in six European countries. BJU Int 97(1):96–100CrossRefPubMed Irwin DE, Milsom I, Kopp Z, Abrams P, Cardozo L (2006) Impact of overactive bladder symptoms on employment, social interactions and emotional well-being in six European countries. BJU Int 97(1):96–100CrossRefPubMed
3.
Zurück zum Zitat Grimby A, Milsom I, Molander U, Wiklund I, Ekelund P (1993) The influence of urinary incontinence on the quality of life of elderly women. Age Ageing 22(2):82–89CrossRefPubMed Grimby A, Milsom I, Molander U, Wiklund I, Ekelund P (1993) The influence of urinary incontinence on the quality of life of elderly women. Age Ageing 22(2):82–89CrossRefPubMed
4.
Zurück zum Zitat Simeonova Z, Milsom I, Kullendorff AM, Molander U, Bengtsson C (1999) The prevalence of urinary incontinence and its influence on the quality of life in women from an urban Swedish population. Acta Obstet Gynecol Scand 78(6):546–551CrossRefPubMed Simeonova Z, Milsom I, Kullendorff AM, Molander U, Bengtsson C (1999) The prevalence of urinary incontinence and its influence on the quality of life in women from an urban Swedish population. Acta Obstet Gynecol Scand 78(6):546–551CrossRefPubMed
5.
Zurück zum Zitat Robinson D, Anders K, Cardozo L, Bidmead J, Dixon A, Balmforth J et al (2003) What do women want? Interpretation of the concept of cure. J Pelvic Med Surg 9:273–277CrossRef Robinson D, Anders K, Cardozo L, Bidmead J, Dixon A, Balmforth J et al (2003) What do women want? Interpretation of the concept of cure. J Pelvic Med Surg 9:273–277CrossRef
6.
Zurück zum Zitat Burgio KL, Nygaard IE, Richter HE, Brubaker L, Gutman RE, Leng W et al (2007) Pelvic Floor Disorders Network. Bladder symptoms 1 year after abdominal sacrocolpopexy with and without Burch colposuspension in women without preoperative stress incontinence symptoms. Am J Obstet Gynecol 197(6):647CrossRefPubMed Burgio KL, Nygaard IE, Richter HE, Brubaker L, Gutman RE, Leng W et al (2007) Pelvic Floor Disorders Network. Bladder symptoms 1 year after abdominal sacrocolpopexy with and without Burch colposuspension in women without preoperative stress incontinence symptoms. Am J Obstet Gynecol 197(6):647CrossRefPubMed
7.
Zurück zum Zitat Brubaker L, Shull BL (2005) EGGS for patient centered outcomes. Int Urogynecol J 16:171–173CrossRef Brubaker L, Shull BL (2005) EGGS for patient centered outcomes. Int Urogynecol J 16:171–173CrossRef
8.
Zurück zum Zitat Srikrishna S, Robinson D, Cardozo L, Cartwright R (2008) Experiences and expectations of women with urogenital prolapse: a quantitative and qualitative exploration. BJOG 115(11):1362–1368CrossRefPubMed Srikrishna S, Robinson D, Cardozo L, Cartwright R (2008) Experiences and expectations of women with urogenital prolapse: a quantitative and qualitative exploration. BJOG 115(11):1362–1368CrossRefPubMed
9.
Zurück zum Zitat Kelleher CJ, Cardozo LD, Khullar V, Salvatore S (1997) A new questionnaire to assess the quality of life of urinary incontinent women. Br J Obstet Gynaecol 104:1374–1379PubMed Kelleher CJ, Cardozo LD, Khullar V, Salvatore S (1997) A new questionnaire to assess the quality of life of urinary incontinent women. Br J Obstet Gynaecol 104:1374–1379PubMed
10.
Zurück zum Zitat Kelleher CJ, Cardozo LD, Khullar V, Salvatore S (1997) A medium-term analysis of the subjective efficacy of treatment for women with detrusor instability and low bladder compliance. Br J Obstet Gynaecol 104(9):988–993PubMed Kelleher CJ, Cardozo LD, Khullar V, Salvatore S (1997) A medium-term analysis of the subjective efficacy of treatment for women with detrusor instability and low bladder compliance. Br J Obstet Gynaecol 104(9):988–993PubMed
11.
Zurück zum Zitat Pelletier EM, Vats V, Clemens JQ (2009) Pharmacotherapy adherence and costs versus nonpharmacologic management in overactive bladder. Am J Manag Care 15(4 Suppl):S108–114PubMed Pelletier EM, Vats V, Clemens JQ (2009) Pharmacotherapy adherence and costs versus nonpharmacologic management in overactive bladder. Am J Manag Care 15(4 Suppl):S108–114PubMed
12.
Zurück zum Zitat Chapple CR, Artibani W, Cardozo LD, Castro-Diaz D, Craggs M, Haab F et al (2005) The role of urinary urgency and its measurement in the overactive bladder symptom syndrome: current concepts and future prospects. BJU Int 95(3):335–340CrossRefPubMed Chapple CR, Artibani W, Cardozo LD, Castro-Diaz D, Craggs M, Haab F et al (2005) The role of urinary urgency and its measurement in the overactive bladder symptom syndrome: current concepts and future prospects. BJU Int 95(3):335–340CrossRefPubMed
13.
Zurück zum Zitat Abrams P (2005) Urgency: the key to defining the overactive bladder. BJU Int 96(Suppl 1):1–3CrossRefPubMed Abrams P (2005) Urgency: the key to defining the overactive bladder. BJU Int 96(Suppl 1):1–3CrossRefPubMed
14.
Zurück zum Zitat Coyne KS, Payne C, Bhattacharyya SK, Revicki DA, Thompson C, Corey R et al (2004) The impact of urinary urgency and frequency on health-related quality of life in overactive bladder: results from a national community survey. Value Health 7(4):455–463CrossRefPubMed Coyne KS, Payne C, Bhattacharyya SK, Revicki DA, Thompson C, Corey R et al (2004) The impact of urinary urgency and frequency on health-related quality of life in overactive bladder: results from a national community survey. Value Health 7(4):455–463CrossRefPubMed
15.
Zurück zum Zitat Artibani W (2007) Outcomes in overactive bladder treatment: patient perception—a key to success. Eur Urol Suppl 6:17–22CrossRef Artibani W (2007) Outcomes in overactive bladder treatment: patient perception—a key to success. Eur Urol Suppl 6:17–22CrossRef
16.
Zurück zum Zitat Cardozo L, Hessdörfer E, Milani R, Arañó P, Dewilde L, Slack M et al (2008) SUNRISE Study Group. Solifenacin in the treatment of urgency and other symptoms of overactive bladder: results from a randomized, double-blind, placebo-controlled, rising-dose trial. BJU Int 102(9):1120–1127CrossRefPubMed Cardozo L, Hessdörfer E, Milani R, Arañó P, Dewilde L, Slack M et al (2008) SUNRISE Study Group. Solifenacin in the treatment of urgency and other symptoms of overactive bladder: results from a randomized, double-blind, placebo-controlled, rising-dose trial. BJU Int 102(9):1120–1127CrossRefPubMed
18.
Zurück zum Zitat Hannestad YS, Rortveit G, Daltveit AK et al (2003) Are smoking and other lifestyle factors associated with female urinary incontinence? The Norwegian EPINCONT Study. BJOG 110(3):247–254CrossRefPubMed Hannestad YS, Rortveit G, Daltveit AK et al (2003) Are smoking and other lifestyle factors associated with female urinary incontinence? The Norwegian EPINCONT Study. BJOG 110(3):247–254CrossRefPubMed
19.
Zurück zum Zitat Arya LA, Myers DL, Jackson ND (2000) Dietary caffeine intake and the risk for detrusor instability: a case-control study. Obstet Gynecol 96(1):85–89CrossRefPubMed Arya LA, Myers DL, Jackson ND (2000) Dietary caffeine intake and the risk for detrusor instability: a case-control study. Obstet Gynecol 96(1):85–89CrossRefPubMed
20.
Zurück zum Zitat Shaya FT, Blume S, Gu A, Zyczynski T, Jumadilova Z (2005) Persistence with overactive bladder pharmacotherapy in a Medicaid population. Am J Manag Care 11(4 Suppl):S121–129PubMed Shaya FT, Blume S, Gu A, Zyczynski T, Jumadilova Z (2005) Persistence with overactive bladder pharmacotherapy in a Medicaid population. Am J Manag Care 11(4 Suppl):S121–129PubMed
21.
Zurück zum Zitat Bourgault C, Sénécal M, Brisson M, Marentette MA, Grégoire JP (2005) Persistence and discontinuation patterns of antihypertensive therapy among newly treated patients: a population-based study. J Hum Hypertens 19(8):607–613CrossRefPubMed Bourgault C, Sénécal M, Brisson M, Marentette MA, Grégoire JP (2005) Persistence and discontinuation patterns of antihypertensive therapy among newly treated patients: a population-based study. J Hum Hypertens 19(8):607–613CrossRefPubMed
22.
Zurück zum Zitat Perreault S, Blais L, Dragomir A, Bouchard MH, Lalonde L, Laurier C et al (2005) Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease. Eur J Clin Pharmacol 61(9):667–674CrossRefPubMed Perreault S, Blais L, Dragomir A, Bouchard MH, Lalonde L, Laurier C et al (2005) Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease. Eur J Clin Pharmacol 61(9):667–674CrossRefPubMed
23.
Zurück zum Zitat Burton G (1994) A randomised crossover trial comparing oxybutynin taken three times a day or taken ‘when needed’. Neurourol Urodyn 13:351–352 Burton G (1994) A randomised crossover trial comparing oxybutynin taken three times a day or taken ‘when needed’. Neurourol Urodyn 13:351–352
24.
26.
Zurück zum Zitat Johannesson M, O’Conor RM, Kobelt-Nguyen G, Mattiasson A (1997) Willingness to pay for reduced incontinence symptoms. Br J Urol 80:557–562PubMed Johannesson M, O’Conor RM, Kobelt-Nguyen G, Mattiasson A (1997) Willingness to pay for reduced incontinence symptoms. Br J Urol 80:557–562PubMed
Metadaten
Titel
Do women with overactive bladder have realistic expectations for therapy?
verfasst von
Arasee Renganathan
Dudley Robinson
Linda Cardozo
Sushma Srikrishna
Rufus Cartwright
Publikationsdatum
01.04.2010
Verlag
Springer-Verlag
Erschienen in
International Urogynecology Journal / Ausgabe 4/2010
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-009-1049-9

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