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Erschienen in: Obesity Surgery 11/2017

24.08.2017 | Review Article

Does Bariatric Surgery Affect the Incidence of Breast Cancer Development? A Systematic Review

verfasst von: Alec A. Winder, Malsha Kularatna, Andrew D. MacCormick

Erschienen in: Obesity Surgery | Ausgabe 11/2017

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Abstract

We reviewed the evidence for bariatric surgery reducing the risk of breast cancer. Data was extracted from multiple libraries, including PubMed, EMBASE, and Medline, to perform a systematic review. Abstracts were reviewed by two independent reviewers. Thirty-eight full-text articles were identified from 1171 abstracts. Four studies were included for meta-analysis; 114 of 10,533 (1.1%) patients receiving bariatric surgery versus 516 of 20,130 (2.6%) controls developed breast cancer, odds ratio 0.564 (95% CI 0.453 to 0.702) using a fixed effects model (P < 0.001) and odds ratio 0.585 (95% CI 0.247 to 1.386) using a random effects model (P 0.223). Bariatric surgery may reduce the risk of breast cancer. More research is required due to heterogeneity of studies, difficulty in identifying accurate controls, and limited follow-up.
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Metadaten
Titel
Does Bariatric Surgery Affect the Incidence of Breast Cancer Development? A Systematic Review
verfasst von
Alec A. Winder
Malsha Kularatna
Andrew D. MacCormick
Publikationsdatum
24.08.2017
Verlag
Springer US
Erschienen in
Obesity Surgery / Ausgabe 11/2017
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-017-2901-5

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