NYC outpatient drug treatment (DT) and opioid treatment programs (OTP) were invited to participate in a pilot evaluation. Newly admitted patients completed counselor-administered surveys at admission, and 90 and 180 days. Surveys included demographic (gender, age, race, language) and clinical items (homelessness, criminal justice involvement, mandated treatment, major health conditions, substance of choice, frequency of use) in addition to the World Health Organization QOL instrument, the WHOQOL-BREF [
1]. The WHOQOL-BREF is a 26-item, validated questionnaire that measures QOL in four domains: physical, psychological, social, and environment. Domain-specific QOL scores were calculated, transformed, and compared with healthy and chronically ill populations from the literature [
2]; scoring was on a scale of 0 to 100 for each domain. We compared mean domain scores between baseline and follow-up intervals for available participants, and by demographic and clinical characteristics using ANOVA and
t-tests. We examined change in QOL scores among OTP participants stratified by major health conditions.