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Erschienen in: Supportive Care in Cancer 2/2018

23.10.2017 | Commentary

Does grip strength decrease in the very early stages of hematological treatment?

verfasst von: C. G. C. Teodozio, G. V. Chaves, I. P. Arcuri, F. T. Frajacomo

Erschienen in: Supportive Care in Cancer | Ausgabe 2/2018

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Abstract

Muscle weakness in hematological cancer patients undergoing acute stages of treatment is an important concern and strong predictor of poor outcomes. However, evidence of strength loss in the very early stages of cancer treatment is not addressed. Here, we found that grip strength was compromised within the first 7 days of hematological treatment (− 2.3 kg, P = 0.002). These findings are novel in elucidating lower handgrip strength in the first week of hematological treatment and encourage additional research focusing on handgrip strength in oncology patients under initial high-dose chemotherapy routine.
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Literatur
1.
Zurück zum Zitat Alibhai SM, Breunis H, Timilshina N, Brignardello-Petersen R, Tomlinson G, Mohamedali H et al (2015) Quality of life and physical function in adults treated with intensive chemotherapy for acute myeloid leukemia improve over time independent of age. J Geriatr Oncol 6:262–271CrossRefPubMed Alibhai SM, Breunis H, Timilshina N, Brignardello-Petersen R, Tomlinson G, Mohamedali H et al (2015) Quality of life and physical function in adults treated with intensive chemotherapy for acute myeloid leukemia improve over time independent of age. J Geriatr Oncol 6:262–271CrossRefPubMed
2.
Zurück zum Zitat Warsame R, Kasi PM, Villasboas-Bisneto JC, Gallenberg D, Wolf R, Ward J et al (2016) Transition of care for inpatient hematology patients receiving chemotherapy: development of hospital discharge huddle process and effects of implementation. J Oncol Pract 12:e88–e94CrossRefPubMed Warsame R, Kasi PM, Villasboas-Bisneto JC, Gallenberg D, Wolf R, Ward J et al (2016) Transition of care for inpatient hematology patients receiving chemotherapy: development of hospital discharge huddle process and effects of implementation. J Oncol Pract 12:e88–e94CrossRefPubMed
3.
Zurück zum Zitat Murnane A, Keogh J, Magat F, Imbesi S, Coulombe M, Patchell S et al (2015) The impact of an inpatient hospital admission on patients’ physical functioning and quality of life in the oncology setting. J Nurs Educ Pract 5:75–82 Murnane A, Keogh J, Magat F, Imbesi S, Coulombe M, Patchell S et al (2015) The impact of an inpatient hospital admission on patients’ physical functioning and quality of life in the oncology setting. J Nurs Educ Pract 5:75–82
4.
Zurück zum Zitat Wall BT, Dirks ML, Snijders T, Senden JM, Dolmans J, van Loon LJ (2014) Substantial skeletal muscle loss occurs during only 5 days of disuse. Acta Physiologica (Oxford, England) 210:600–611CrossRef Wall BT, Dirks ML, Snijders T, Senden JM, Dolmans J, van Loon LJ (2014) Substantial skeletal muscle loss occurs during only 5 days of disuse. Acta Physiologica (Oxford, England) 210:600–611CrossRef
5.
Zurück zum Zitat Bodilsen AC, Pedersen MM, Petersen J, Beyer N, Andersen O, Smith LL et al (2013) Acute hospitalization of the older patient: changes in muscle strength and functional performance during hospitalization and 30 days after discharge. Am J Phys Med Rehabil 92:789–796CrossRefPubMed Bodilsen AC, Pedersen MM, Petersen J, Beyer N, Andersen O, Smith LL et al (2013) Acute hospitalization of the older patient: changes in muscle strength and functional performance during hospitalization and 30 days after discharge. Am J Phys Med Rehabil 92:789–796CrossRefPubMed
6.
Zurück zum Zitat Alibhai SM, O'Neill S, Fisher-Schlombs K, Breunis H, Timilshina N, Brandwein JM et al (2014) A pilot phase II RCT of a home-based exercise intervention for survivors of AML. Support Care Cancer : Off J Multinat Assoc Support Care Cancer 22:881–889CrossRef Alibhai SM, O'Neill S, Fisher-Schlombs K, Breunis H, Timilshina N, Brandwein JM et al (2014) A pilot phase II RCT of a home-based exercise intervention for survivors of AML. Support Care Cancer : Off J Multinat Assoc Support Care Cancer 22:881–889CrossRef
7.
Zurück zum Zitat Humphreys J, de la Maza P, Hirsch S, Barrera G, Gattas V, Bunout D (2002) Muscle strength as a predictor of loss of functional status in hospitalized patients. Nutrition 18:616–620CrossRefPubMed Humphreys J, de la Maza P, Hirsch S, Barrera G, Gattas V, Bunout D (2002) Muscle strength as a predictor of loss of functional status in hospitalized patients. Nutrition 18:616–620CrossRefPubMed
8.
Zurück zum Zitat Chen CH, Ho C, Huang YZ, Hung TT (2011) Hand-grip strength is a simple and effective outcome predictor in esophageal cancer following esophagectomy with reconstruction: a prospective study. J Cardiothorac Surg 6:98CrossRefPubMedPubMedCentral Chen CH, Ho C, Huang YZ, Hung TT (2011) Hand-grip strength is a simple and effective outcome predictor in esophageal cancer following esophagectomy with reconstruction: a prospective study. J Cardiothorac Surg 6:98CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Kilgour RD, Vigano A, Trutschnigg B, Lucar E, Borod M, Morais JA (2013) Handgrip strength predicts survival and is associated with markers of clinical and functional outcomes in advanced cancer patients. Support Care Cancer : Off J Multinat Assoc Support Care Cancer 21:3261–3270CrossRef Kilgour RD, Vigano A, Trutschnigg B, Lucar E, Borod M, Morais JA (2013) Handgrip strength predicts survival and is associated with markers of clinical and functional outcomes in advanced cancer patients. Support Care Cancer : Off J Multinat Assoc Support Care Cancer 21:3261–3270CrossRef
10.
Zurück zum Zitat Lakenman P, Ottens-Oussoren K, Witvliet-van Nierop J, van der Peet D, de van der Schueren M (2017) Handgrip Strength Is Associated With Treatment Modifications During Neoadjuvant Chemoradiation in Patients With Esophageal Cancer Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition: 884533617700862 Lakenman P, Ottens-Oussoren K, Witvliet-van Nierop J, van der Peet D, de van der Schueren M (2017) Handgrip Strength Is Associated With Treatment Modifications During Neoadjuvant Chemoradiation in Patients With Esophageal Cancer Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition: 884533617700862
11.
Zurück zum Zitat Kramer M, Heussner P, Herzberg PY, Andree H, Hilgendorf I, Leithaeuser M et al (2013) Validation of the grip test and human activity profile for evaluation of physical performance during the intermediate phase after allogeneic hematopoietic stem cell transplantation. Support Care Cancer: Off J Multinat Assoc Support Care Cancer 21:1121–1129CrossRef Kramer M, Heussner P, Herzberg PY, Andree H, Hilgendorf I, Leithaeuser M et al (2013) Validation of the grip test and human activity profile for evaluation of physical performance during the intermediate phase after allogeneic hematopoietic stem cell transplantation. Support Care Cancer: Off J Multinat Assoc Support Care Cancer 21:1121–1129CrossRef
12.
Zurück zum Zitat Morishita S, Kaida K, Yamauchi S, Sota K, Ishii S, Ikegame K et al (2013) Relationship between corticosteroid dose and declines in physical function among allogeneic hematopoietic stem cell transplantation patients. Support Care Cancer: Off J Multinat Assoc Support Care Cancer 21:2161–2169CrossRef Morishita S, Kaida K, Yamauchi S, Sota K, Ishii S, Ikegame K et al (2013) Relationship between corticosteroid dose and declines in physical function among allogeneic hematopoietic stem cell transplantation patients. Support Care Cancer: Off J Multinat Assoc Support Care Cancer 21:2161–2169CrossRef
13.
Zurück zum Zitat Tanaka S, Imataki O, Kitaoka A, Fujioka S, Hanabusa E, Ohbayashi Y et al (2017) Clinical impact of sarcopenia and relevance of nutritional intake in patients before and after allogeneic hematopoietic stem cell transplantation. J Cancer Res Clin Oncol 143:1083–1092CrossRefPubMed Tanaka S, Imataki O, Kitaoka A, Fujioka S, Hanabusa E, Ohbayashi Y et al (2017) Clinical impact of sarcopenia and relevance of nutritional intake in patients before and after allogeneic hematopoietic stem cell transplantation. J Cancer Res Clin Oncol 143:1083–1092CrossRefPubMed
14.
Zurück zum Zitat Mohamedali H, Breunis H, Timilshina N, Brandwein JM, Gupta V, Minden MD et al (2012) Older age is associated with similar quality of life and physical function compared to younger age during intensive chemotherapy for acute myeloid leukemia. Leuk Res 36:1241–1248CrossRefPubMed Mohamedali H, Breunis H, Timilshina N, Brandwein JM, Gupta V, Minden MD et al (2012) Older age is associated with similar quality of life and physical function compared to younger age during intensive chemotherapy for acute myeloid leukemia. Leuk Res 36:1241–1248CrossRefPubMed
15.
Zurück zum Zitat Fess EE (1992) Clinical assessment recommendations. In: JS IC (ed) American society of hand therapist, pp. 41–45 Fess EE (1992) Clinical assessment recommendations. In: JS IC (ed) American society of hand therapist, pp. 41–45
16.
Zurück zum Zitat Kilgour RD, Vigano A, Trutschnigg B, Hornby L, Lucar E, Bacon SL et al (2010) Cancer-related fatigue: the impact of skeletal muscle mass and strength in patients with advanced cancer. J Cachexia Sarcopenia Muscle 1:177–185CrossRefPubMedPubMedCentral Kilgour RD, Vigano A, Trutschnigg B, Hornby L, Lucar E, Bacon SL et al (2010) Cancer-related fatigue: the impact of skeletal muscle mass and strength in patients with advanced cancer. J Cachexia Sarcopenia Muscle 1:177–185CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Clark BC, Manini TM (2008) Sarcopenia≠dynapenia. J Gerontol Ser A, Biolog Sci Med Sci 63:829–834CrossRef Clark BC, Manini TM (2008) Sarcopenia≠dynapenia. J Gerontol Ser A, Biolog Sci Med Sci 63:829–834CrossRef
18.
Zurück zum Zitat Makuuchi R, Sugisawa N, Kaji S, Hikage M, Tokunaga M, Tanizawa Y et al (2017) Enhanced recovery after surgery for gastric cancer and an assessment of preoperative carbohydrate loading. Eur J Surg Oncol: J Eur Soc Surg Oncol British Assoc Surg Oncol 43:210–217CrossRef Makuuchi R, Sugisawa N, Kaji S, Hikage M, Tokunaga M, Tanizawa Y et al (2017) Enhanced recovery after surgery for gastric cancer and an assessment of preoperative carbohydrate loading. Eur J Surg Oncol: J Eur Soc Surg Oncol British Assoc Surg Oncol 43:210–217CrossRef
19.
Zurück zum Zitat Gould DW, Lahart I, Carmichael AR, Koutedakis Y, Metsios GS (2013) Cancer cachexia prevention via physical exercise: molecular mechanisms. J Cachexia Sarcopenia Muscle 4:111–124CrossRefPubMed Gould DW, Lahart I, Carmichael AR, Koutedakis Y, Metsios GS (2013) Cancer cachexia prevention via physical exercise: molecular mechanisms. J Cachexia Sarcopenia Muscle 4:111–124CrossRefPubMed
20.
Zurück zum Zitat Bergenthal N, Will A, Streckmann F, Wolkewitz KD, Monsef I, Engert A et al (2014) Aerobic physical exercise for adult patients with haematological malignancies. Cochrane database Syst Rev 11:CD009075 Bergenthal N, Will A, Streckmann F, Wolkewitz KD, Monsef I, Engert A et al (2014) Aerobic physical exercise for adult patients with haematological malignancies. Cochrane database Syst Rev 11:CD009075
Metadaten
Titel
Does grip strength decrease in the very early stages of hematological treatment?
verfasst von
C. G. C. Teodozio
G. V. Chaves
I. P. Arcuri
F. T. Frajacomo
Publikationsdatum
23.10.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 2/2018
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-017-3932-0

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