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Quality of Life Research

Erschienen in:

04.03.2019

Does inappropriate prescribing affect elderly patients’ quality of life? A study from a Malaysian tertiary hospital

verfasst von: Muhammad Eid Akkawi, Mohamad Haniki Nik Mohamed, Mohd Aznan Md Aris

Erschienen in: Quality of Life Research | Ausgabe 7/2019

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Abstract

Purpose

To investigate the association between potentially inappropriate medication (PIM)/potential prescribing omission (PPO) and the health-related quality of life (HRQoL) among community-dwelling hospitalized elderly patients.

Methods

This is a cross-sectional study that took place in a Malaysian tertiary hospital. Patients ≥ 65 years old with at least one medication on admission were recruited. The patients’ prehospitalization medications were reviewed to identify PIMs/PPOs using version 2 of the STOPP/START criteria. HRQoL was assessed using the EuroQol-5 dimensions (EQ-5D) and EuroQol-visual analog scale (EQ-VAS). The association between the presence of PIM/PPO and the patients’ HRQoL was analyzed using Chi-square and Mann–Whitney U tests. Multiple linear regression models were applied to determine the effect of exposure to PIM/PPO on the patients’ HRQoL, adjusting for confounders.

Results

Out of 517 patients who fulfilled the inclusion criteria, 502 patients (97%) accepted to be involved in the study and completed the HRQoL questionnaire. The mean (SD) age was 72.4 (5.9) years. 393 (78.3%) of the patients had problems in at least one EQ-5D dimension with pain/discomfort problem being the most reported complaint. The mean (SD) values of the EQ-5D index and the EQ-VAS were 0.734 (0.214) and 59.6 (14.2), respectively, which are lower than those seen in the general Malaysian population. PIM and PPO were found in 28.5% and 45.6% of the patients, respectively. No significant differences were found in the EQ-5D dimensions, EQ-5D index and EQ-VAS between patients who had PIM/PPO and those who did not. Age, sex, and comorbidities were significantly associated with the patients’ HRQoL.

Conclusion

PIM and PPO are not uncommon among hospitalized elderly patients; however, it does not significantly affect their HRQoL as measured by the EQ-5D-3L instrument.

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Titel: Does inappropriate prescribing affect elderly patients’ quality of life? A study from a Malaysian tertiary hospital
verfasst von: Muhammad Eid Akkawi
Mohamad Haniki Nik Mohamed
Mohd Aznan Md Aris
Publikationsdatum: 04.03.2019
Verlag: Springer International Publishing
Erschienen in: Quality of Life Research / Ausgabe 7/2019
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-019-02153-5

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

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