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Erschienen in: Journal of Neural Transmission 4/2019

13.02.2019 | Psychiatry and Preclinical Psychiatric Studies - Review Article

Dopamine in psychiatry: a historical perspective

verfasst von: Paul Bernard Foley

Erschienen in: Journal of Neural Transmission | Ausgabe 4/2019

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Abstract

Dopamine is the principal transmitter of several central nervous system pathways originating in the midbrain and critically involved in motor activity, learning and motivation, disruptions of which have been implicated in a number of disorders, including Parkinson disease and schizophrenia. Dopamine played a particularly significant role in the history of neurochemistry. Following a series of investigations between 1957 and 1965, commencing in the laboratory and completed in the clinic, the significance of chemical neurotransmission for normal CNS function was first demonstrated in the case of dopamine.
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Metadaten
Titel
Dopamine in psychiatry: a historical perspective
verfasst von
Paul Bernard Foley
Publikationsdatum
13.02.2019
Verlag
Springer Vienna
Erschienen in
Journal of Neural Transmission / Ausgabe 4/2019
Print ISSN: 0300-9564
Elektronische ISSN: 1435-1463
DOI
https://doi.org/10.1007/s00702-019-01987-0

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