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Strahlentherapie und Onkologie

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31.03.2021 | Original Article

Dosimetric comparison of volumetric modulated arc therapy (VMAT) and high-dose-rate brachytherapy (HDR-BT) for superficial skin irradiation with significant curvature in one or more planes

verfasst von: Rachel J. Wills, Gerry Lowe, Caroline L. Jones, Peter J. Hoskin

Erschienen in: Strahlentherapie und Onkologie | Ausgabe 6/2021

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Abstract

Purpose

This study compares the plan quality of high-dose-rate brachytherapy (HDR-BT) and volumetric modulated arc therapy (VMAT) for superficial irradiation of large areas of skin with significant curvature in one or more planes.

Methods

A total of 14 patients from two centres previously treated with either HDR-BT or VMAT were retrospectively replanned using the alternative technique. Sites included scalp and lower limbs. Identical computed tomography (CT) scans, clinical target volume (CTV) and organs at risk (OARs) and prescription were used for both techniques. Conformity, skin surface dose and OAR doses were compared.

Results

Conformity index was consistently better with VMAT than HDR-BT (p < 0.01). Maximum skin surface dose (D0.1cc) had a higher mean of 49.6 Gy with HDR-BT compared to 31.4 Gy for VMAT (p < 0.01). Significantly smaller volumes of healthy tissue were irradiated with VMAT than with HDR-BT. This can be seen in brain volumes receiving 10, 20 and 30 Gy EQD2 and in extremities receiving 5 and 10 Gy. When close to the volume, the lens received significantly lower doses with VMAT (p < 0.01).

Conclusion

In this small sample, VMAT gives equal coverage with lower OAR and skin surface doses than HDR-BT for both scalp and extremities. VMAT is a useful technique for treating large, superficial volumes with significant curvature in one or more planes.

Able CM, Mills MD, McNeese MD, Hogstrom KR (1991) Evaluation of a total scalp electron irradiation technique. Int J Radiat Oncol Biol Phys 21:1063–1072. https://doi.org/10.1016/0360-3016(91)90751-OCrossRefPubMed

Mellenberg D, Schoeppel S (1993) Total scalp irradiation of mycosis fungoides: the 4x4 technique. Int J Radiat Oncol Biol Phys 27:953–958. https://doi.org/10.1016/0360-3016(93)90473-9CrossRefPubMed

Tung S, Shiu A, Starkschall G et al (1993) Dosimetric evaluation of total scalp irradiation using a lateral electron-photon technique. Int J Radiat Oncol Biol Phys 27:153–160. https://doi.org/10.1016/0360-3016(93)90433-VCrossRefPubMed

Guinot JL, Rembielak A, Perez-Calatayud J et al (2018) GEC-ESTRO ACROP recommendations in skin brachytherapy. Radiother Oncol 126:377–385. https://doi.org/10.1016/j.radonc.2018.01.013CrossRefPubMed

Ouhib Z, Kasper M, Calatayud PJ, Rodriguez S et al (2015) Aspects of dosimetry and clinical practice of skin brachytherapy: the American Brachytherapy Society working group report. Brachytherapy 14:840–858. https://doi.org/10.1016/j.brachy.2015.06.005CrossRefPubMed

Zaorsky NG, Lee CT, Zhang E et al (2017) Skin CanceR Brachytherapy vs External beam radiation therapy (SCRiBE) meta-analysis. Radiother Oncol 126:386–393. https://doi.org/10.1016/j.radonc.2017.12.029CrossRef

Paddick I (2000) A simple scoring ratio to index the conformity of radiosurgical treatment plans. J Neurosurg 93(Suppl 3):219–222. https://doi.org/10.3171/jns.2000.93.supplement_3.0219CrossRefPubMed

Joiner MC, Bentzen SM (2002) Chapter 12: Time-dose relationships: the linear quadratic approach. In: Steel G (ed) Basic Clinical Radiobiology, 3rd edn. Hodder Arnold, London, pp 120–133

Alam M, Nanda S, Mittal B et al (2011) The use of brachytherapy in the treatment of nonmelanoma skin cancer: a review. J Am Acad Dermatol. https://doi.org/10.1016/j.jaad.2010.03.027CrossRefPubMed

10.

Paravati AJ, Hawkins PG, Martin AN et al (2015) Clinical and cosmetic outcomes in patients treated with high-dose-rate electronic brachytherapy for nonmelanoma skin cancer. Pract Radiat Oncol 5:e659–e664. https://doi.org/10.1016/j.prro.2015.07.002CrossRefPubMed

11.

Safigholi H, Song WY, Meigooni AS (2015) Optimum radiation source for radiation therapy of skin cancer. J App Clin Med Phys 16:219–227. https://doi.org/10.1120/jacmp.v16i5.5407CrossRef

12.

Orton N, Jaradat H, Welsh J et al (2005) Total scalp irradiation using helical tomotherapy. Med Dosim 30:162–168. https://doi.org/10.1016/j.meddos.2005.05.002CrossRefPubMed

13.

Bedford JL, Childs PJ, Hansen VN et al (2005) Treatment of extensive scalp lesions with segmental intensity-modulated photon therapy. Int J Radiat Oncol Biol Phys 62:1549–1558. https://doi.org/10.1016/j.ijrobp.2005.04.001CrossRefPubMed

14.

Wojcicka JB, Lasher DE, McAfee SS, Fortier GA (2009) Dosimetric comparison of three different treatment techniques in extensive scalp lesion irradiation. Radiother Oncol 91:255–260. https://doi.org/10.1016/j.radonc.2008.09.022CrossRefPubMed

15.

Locke J, Low DA, Grigireit T et al (2002) Potenzial of tomotherapy for total scalp treatment. Int J Radiat Oncol Biol Phys 52:553–559. https://doi.org/10.1016/S0360-3016(01)02593-7CrossRefPubMed

16.

Haraldsson A, Engleson J, Bäck S et al (2019) J Appl Clin Med Phys 20(5):44–54. https://doi.org/10.1002/acm2.12579CrossRefPubMedPubMedCentral

17.

Sarfehnia A, Poon E, Davis S et al (2014) A novel approach to total skin irradiation using helical TomoTherapy. Pract Radiat Oncol 4:330–335. https://doi.org/10.1016/j.prro.2013.10.004CrossRefPubMed

18.

Schaff EM, Rosenberg SA, Olsen SJ et al (2018) Bone marrow suppression as a complication of total skin helical tomotherapy in the treatment of mycosis fungoides. Radiat Oncol 13:67. https://doi.org/10.1186/s13014-018-1013-2

19.

Ho Song J, Jung J‑Y, Hyung-Wook P et al (2015) Dosimetric comparison of three different treatment modalities for total scalp irradiation: the conventional lateral photon-electron technique, helical tomotherapy, and volumetric-modulated arc therapy. J Radiat Res 56:717–726. https://doi.org/10.1093/jrr/rru049CrossRef

20.

Boman E, Paterson D et al (2018) Dosimetric comparison of surface mould HDR brachytherapy with VMAT. J Med Radiat Sci 65:311–318. https://doi.org/10.1002/jmrs.301CrossRefPubMedPubMedCentral

21.

Ostheimer C, Hübsch P, Janich M et al (2016) Dosimetric comparison of intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) in total scalp irradiation: a single institution experience. Radiat Oncol J 34:313–321. https://doi.org/10.3857/roj.2016.01935CrossRefPubMedPubMedCentral

22.

Hu J, Xiou W, He Z et al (2014) Target-splitting non-coplanar RapidArc radiation therapy for a diffuse sebaceous carcimoma of the scalp: a novel delivery technique. Radiat Oncol 9:204. https://doi.org/10.1186/1748-717X-9-204CrossRefPubMedPubMedCentral

23.

Park JM, Kim IH, Ye SJ, Kim K (2014) Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi’s sarcoma developed on the skin of feet. J Appl Clin Med Phys 15:173–187. https://doi.org/10.1120/jacmp.v15i6.4970CrossRefPubMedCentral

24.

Archambeau JO, Pezner R, Wasserman T (1995) Pathophysiology of irradiated skin and breast. Int J Radiat Oncol Biol Phys 31:1171–1185. https://doi.org/10.1016/0360-3016(94)00423-ICrossRefPubMed

25.

Graneroa D, Perez-Calatayud J, Vijande J et al (2014) Limitations of the TG-43 formalism for skin high-dose-rate brachytherapy dose calculations. Med Phys 41:21703. https://doi.org/10.1118/1.4860175CrossRef

26.

Boman EL, Satherley TWS, Schleich N et al (2017) The validity of Acuros BV and TG-43 for high-dose-rate brachytherapy superficial mold treatments. Brachytherapy 16:1280–1288. https://doi.org/10.1016/j.brachy.2017.08.010CrossRefPubMed

27.

Beaulieu L, Carlsson Tedgren A, Carrier JF et al (2012) Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: current status and recommendations for clinical implementation. Med Phys 39:6208–6236. https://doi.org/10.1118/1.4747264CrossRefPubMed

Titel: Dosimetric comparison of volumetric modulated arc therapy (VMAT) and high-dose-rate brachytherapy (HDR-BT) for superficial skin irradiation with significant curvature in one or more planes
verfasst von: Rachel J. Wills
Gerry Lowe
Caroline L. Jones
Peter J. Hoskin
Publikationsdatum: 31.03.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: Strahlentherapie und Onkologie / Ausgabe 6/2021
Print ISSN: 0179-7158
Elektronische ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-021-01759-4

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Dosimetric comparison of volumetric modulated arc therapy (VMAT) and high-dose-rate brachytherapy (HDR-BT) for superficial skin irradiation with significant curvature in one or more planes

Abstract

Purpose

Methods

Results

Conclusion

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

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