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Erschienen in: The International Journal of Cardiovascular Imaging 2/2014

01.12.2014 | Original Paper

Dual-energy CT for differentiating acute and chronic pulmonary thromboembolism: an initial experience

verfasst von: Seung-seob Kim, Jin Hur, Young Jin Kim, Hye-Jeong Lee, Yoo Jin Hong, Byoung Wook Choi

Erschienen in: The International Journal of Cardiovascular Imaging | Sonderheft 2/2014

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Abstract

The purpose of this study was to prospectively evaluate the diagnostic capability of single-phase dual-energy CT (DECT) angiography to differentiate acute and chronic pulmonary thromboembolism (APTE, CPTE). We prospectively enrolled 26 patients (M:F = 9:17; mean age, 61 years old) with a filling defect in the pulmonary artery on DECT angiography. They were divided into two groups—APTE and CPTE—based on the clinical criteria. Two investigators quantitatively measured the following parameters at the embolism and main pulmonary artery: CT attenuation density [Hounsfield unit (HU) values], iodine-related HU value (IHU), and iodine concentration (IC, mg/ml). These parameters of the embolism and their ratio divided by those of the main pulmonary artery were compared between APTE and CPTE groups. Among 26 patients, 15 were categorized into the APTE group and 11 into the CPTE group. The mean HU, IHU, and IC values of emboli were significantly different between the APTE and CPTE groups (32.2 ± 17.0 vs. 52.1 ± 13.6 HU; P = 0.016, 7.2 ± 2.8 vs. 27.3 ± 12.7 HU; P < 0.001, and 0.57 ± 0.23 vs. 1.56 ± 0.67; P < 0.001). The mean HU, IHU, and IC ratios between emboli and main pulmonary arteries were also significantly different between the two groups (0.085 ± 0.046 vs. 0.156 ± 0.064 HU; P = 0.003, 0.023 ± 0.013 vs. 0.099 ± 0.053; P < 0.001, and 0.048 ± 0.035 vs. 0.130 ± 0.064; P = 0.001). DECT angiography using a quantitative analytic methodology can be used to differentiate between APTE and CPTE.
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Metadaten
Titel
Dual-energy CT for differentiating acute and chronic pulmonary thromboembolism: an initial experience
verfasst von
Seung-seob Kim
Jin Hur
Young Jin Kim
Hye-Jeong Lee
Yoo Jin Hong
Byoung Wook Choi
Publikationsdatum
01.12.2014
Verlag
Springer Netherlands
Erschienen in
The International Journal of Cardiovascular Imaging / Ausgabe Sonderheft 2/2014
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-014-0508-7

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