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19.02.2021 | Guidelines Open Access

E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET

Zeitschrift:
European Journal of Nuclear Medicine and Molecular Imaging
Autoren:
Francesco Ceci, Daniela E. Oprea-Lager, Louise Emmett, Judit A. Adam, Jamshed Bomanji, Johannes Czernin, Matthias Eiber, Uwe Haberkorn, Michael S. Hofman, Thomas A. Hope, Rakesh Kumar, Steven P. Rowe, Sarah M. Schwarzenboeck, Stefano Fanti, Ken Herrmann
Wichtige Hinweise

Supplementary Information

The online version contains supplementary material available at https://​doi.​org/​10.​1007/​s00259-021-05245-y.
This article is part of the Topical Collection on Oncology – Genitourinary
Stefano Fanti and Ken Herrmann are co-senior authors of this project.

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Rationale

The development of consensus guidelines for interpretation of Prostate-Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) is needed to provide more consistent reports in clinical practice. The standardization of PSMA-PET interpretation may also contribute to increasing the data reproducibility within clinical trials. Finally, guidelines in PSMA-PET interpretation are needed to communicate the exact location of findings to referring physicians, to support clinician therapeutic management decisions.

Methods

A panel of worldwide experts in PSMA-PET was established. Panelists were selected based on their expertise and publication record in the diagnosis or treatment of PCa, in their involvement in clinical guidelines and according to their expertise in the clinical application of radiolabeled PSMA inhibitors. Panelists were actively involved in all stages of a modified, nonanonymous, Delphi consensus process.

Results

According to the findings obtained by modified Delphi consensus process, panelist recommendations were implemented in a structured report for PSMA-PET.

Conclusions

The E-PSMA standardized reporting guidelines, a document supported by the European Association of Nuclear Medicine (EANM), provide consensus statements among a panel of experts in PSMA-PET imaging, to develop a structured report for PSMA-PET in prostate cancer and to harmonize diagnostic interpretation criteria.

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