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Erschienen in: Lung 4/2018

29.05.2018 | INTERVENTIONAL BRONCHOSCOPY

EBUS-TBNA is Sufficient for Successful Diagnosis of Silicosis with Mediastinal Lymphadenopathy

verfasst von: David Shitrit, Yochai Adir, Avital Avriel, Daniel King, Gali Epstein Shochet, Alexander Guber, Sonia Schnaer, Michael Kassirer, Paul D. Blanc, Amir Abramovich

Erschienen in: Lung | Ausgabe 4/2018

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Abstract

Background

Silicosis is an occupational lung disease resulting from inhalation of respirable crystalline silica. Recently, an international silicosis epidemic has been noted among artificial stone workers.

Objective

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is currently used for patients with unexplained lymphadenopathy. Since silicosis may present with prominent lymphadenopathy, the diagnostic yield of EBUS-TBNA in diagnosing silicosis was evaluated.

Methods

Twenty-eight patients with suspected silicosis referred for outpatient evaluation in three large tertiary hospitals were evaluated. Patients with mediastinal lymphadenopathy underwent EBUS-TBNA, while others underwent TBB and/or video-assisted thoracoscopic surgery (VATS).

Results

Eleven patients with mediastinal lymphadenopathy (39%) were evaluated using EBUS-TBNA. The diagnosis was accurate in all cases, demonstrating silica particles under polarized light, with no complications. Among the remaining patients, TBB was only 76% diagnostic, therefore requiring VATS.

Conclusions

EBUS-TBNA is a useful and sufficient tool to diagnose silicosis in patients with mediastinal lymphadenopathy along compatible exposure histories.
Literatur
2.
Zurück zum Zitat Cowie RL, Murray J, Becklake MR (2010) Pneumoconioses and other mineral dust-related diseases. In: Murray and Nadel’s textbook of respiratory medicine. Saunders Elsevier, Philadelphia Cowie RL, Murray J, Becklake MR (2010) Pneumoconioses and other mineral dust-related diseases. In: Murray and Nadel’s textbook of respiratory medicine. Saunders Elsevier, Philadelphia
3.
Zurück zum Zitat Langer AM (1986) Mineralogy. In: Occupational respiratory diseases. US Department of Health and Human Services (Center of Disease Control), Washington, DC, pp 3–40 Langer AM (1986) Mineralogy. In: Occupational respiratory diseases. US Department of Health and Human Services (Center of Disease Control), Washington, DC, pp 3–40
4.
Zurück zum Zitat Kramer MR, Blanc PD, Fireman E et al (2012) Artificial stone silicosis [corrected]: disease resurgence among artificial stone workers. Chest 142:419–424CrossRefPubMed Kramer MR, Blanc PD, Fireman E et al (2012) Artificial stone silicosis [corrected]: disease resurgence among artificial stone workers. Chest 142:419–424CrossRefPubMed
5.
Zurück zum Zitat Adams K, Shah PL, Edmonds L et al (2009) Test performance of endobronchial ultrasound and transbronchial needle aspiration biopsy for mediastinal staging in patients with lung cancer: systematic review and meta-analysis. Thorax 64:757–762CrossRefPubMed Adams K, Shah PL, Edmonds L et al (2009) Test performance of endobronchial ultrasound and transbronchial needle aspiration biopsy for mediastinal staging in patients with lung cancer: systematic review and meta-analysis. Thorax 64:757–762CrossRefPubMed
6.
Zurück zum Zitat Kang HK, Um SW, Jeong BH et al (2016) The utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with small-cell lung cancer. Intern Med 55:1061–1066CrossRefPubMed Kang HK, Um SW, Jeong BH et al (2016) The utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with small-cell lung cancer. Intern Med 55:1061–1066CrossRefPubMed
8.
Zurück zum Zitat Rusch VW, Asamura H, Watanabe H et al (2009) The IASLC lung cancer staging project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer. J Thorac Oncol 4:568–577CrossRefPubMed Rusch VW, Asamura H, Watanabe H et al (2009) The IASLC lung cancer staging project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer. J Thorac Oncol 4:568–577CrossRefPubMed
9.
Zurück zum Zitat Herth FJ, Eberhardt R, Vilmann P et al (2006) Real-time endobronchial ultrasound guided transbronchial needle aspiration for sampling mediastinal lymph nodes. Thorax 61:795–798CrossRefPubMedPubMedCentral Herth FJ, Eberhardt R, Vilmann P et al (2006) Real-time endobronchial ultrasound guided transbronchial needle aspiration for sampling mediastinal lymph nodes. Thorax 61:795–798CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Matsumoto S, Mori H, Miyake H et al (1998) MRI signal characteristics of progressive massive fibrosis in silicosis. Clin Radiol 53:510–514CrossRefPubMed Matsumoto S, Mori H, Miyake H et al (1998) MRI signal characteristics of progressive massive fibrosis in silicosis. Clin Radiol 53:510–514CrossRefPubMed
11.
Zurück zum Zitat Dhagat PK, Singh S, Jain M et al (2017) Thoracic sarcoidosis: imaging with high resolution computed tomography. J Clin Diagn Res 11:TC15–TC18PubMedPubMedCentral Dhagat PK, Singh S, Jain M et al (2017) Thoracic sarcoidosis: imaging with high resolution computed tomography. J Clin Diagn Res 11:TC15–TC18PubMedPubMedCentral
12.
Zurück zum Zitat Lung Transplant Group (1992) Single lung transplantation for end-stage silicosis: report of a case. J Formos Med Assoc 91:926–932 Lung Transplant Group (1992) Single lung transplantation for end-stage silicosis: report of a case. J Formos Med Assoc 91:926–932
13.
Zurück zum Zitat Demoulin AS, Hermans G, Gustin M (2009) An unusual interstitial pneumonitis. Rev Med Liege 64:373–376PubMed Demoulin AS, Hermans G, Gustin M (2009) An unusual interstitial pneumonitis. Rev Med Liege 64:373–376PubMed
14.
Zurück zum Zitat Chida M, Fukuda H, Araki O et al (2010) Lung transplantation for aspiration-induced silicosis of the lung. Gen Thorac Cardiovasc Surg 58:141–143CrossRefPubMed Chida M, Fukuda H, Araki O et al (2010) Lung transplantation for aspiration-induced silicosis of the lung. Gen Thorac Cardiovasc Surg 58:141–143CrossRefPubMed
15.
Zurück zum Zitat Detterbeck FC, Lewis SZ, Diekemper R et al (2013) Executive summary: diagnosis and management of lung cancer, 3rd ed.: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 143:7S–37SCrossRefPubMed Detterbeck FC, Lewis SZ, Diekemper R et al (2013) Executive summary: diagnosis and management of lung cancer, 3rd ed.: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 143:7S–37SCrossRefPubMed
16.
Zurück zum Zitat De Leyn P, Dooms C, Kuzdzal J et al (2014) Revised ESTS guidelines for preoperative mediastinal lymph node staging for non-small-cell lung cancer. Eur J Cardiothorac Surg 45:787–798CrossRefPubMed De Leyn P, Dooms C, Kuzdzal J et al (2014) Revised ESTS guidelines for preoperative mediastinal lymph node staging for non-small-cell lung cancer. Eur J Cardiothorac Surg 45:787–798CrossRefPubMed
17.
Zurück zum Zitat Du Rand IA, Barber PV, Goldring J et al (2011) British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults. Thorax 66(Suppl 3):iii1–iii21CrossRefPubMed Du Rand IA, Barber PV, Goldring J et al (2011) British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults. Thorax 66(Suppl 3):iii1–iii21CrossRefPubMed
18.
Zurück zum Zitat Tung AH, Ngai JC, Ko FW et al (2013) Diagnosis of silicotuberculosis by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA). Respirology 18:383–384CrossRefPubMed Tung AH, Ngai JC, Ko FW et al (2013) Diagnosis of silicotuberculosis by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA). Respirology 18:383–384CrossRefPubMed
19.
Zurück zum Zitat Wallace MB, Pascual JM, Raimondo M et al (2008) Minimally invasive endoscopic staging of suspected lung cancer. JAMA 299:540–546CrossRefPubMed Wallace MB, Pascual JM, Raimondo M et al (2008) Minimally invasive endoscopic staging of suspected lung cancer. JAMA 299:540–546CrossRefPubMed
20.
Zurück zum Zitat Jalil BA, Yasufuku K, Khan AM (2015) Uses, limitations, and complications of endobronchial ultrasound. Baylor Univ Med Cent Proc 28:325–330CrossRef Jalil BA, Yasufuku K, Khan AM (2015) Uses, limitations, and complications of endobronchial ultrasound. Baylor Univ Med Cent Proc 28:325–330CrossRef
Metadaten
Titel
EBUS-TBNA is Sufficient for Successful Diagnosis of Silicosis with Mediastinal Lymphadenopathy
verfasst von
David Shitrit
Yochai Adir
Avital Avriel
Daniel King
Gali Epstein Shochet
Alexander Guber
Sonia Schnaer
Michael Kassirer
Paul D. Blanc
Amir Abramovich
Publikationsdatum
29.05.2018
Verlag
Springer US
Erschienen in
Lung / Ausgabe 4/2018
Print ISSN: 0341-2040
Elektronische ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-018-0129-3

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