Excerpt

A 5-day-old term baby presented in cardiogenic shock due to Coxsackie type B myocarditis complicated by refractory atrial arrhythmias and acute hepatic and renal failure. The initial echocardiogram revealed severe ventricular dysfunction with diffuse hyperechogenic foci (Supplementary Videos 1 and 2, Fig. 1). Despite aggressive medical therapy, his hemodynamic status deteriorated, requiring mechanical circulatory support initially with extracorporeal membrane oxygenation, which was subsequently replaced with a left ventricular assist device (Berlin heart). After 35 days on the assist device, the patient underwent successful cardiac transplantation. The explanted heart had myocardial dystrophic calcification by gross examination (Fig. 2) and histology (Fig. 3).

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