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01.11.2018 | Echocardiography (JM Gardin and AH Waller, Section Editors) | Ausgabe 11/2018

Current Cardiology Reports 11/2018

Echocardiography in Sarcoidosis

Zeitschrift:
Current Cardiology Reports > Ausgabe 11/2018
Autoren:
Reto Kurmann, Sunil V. Mankad, Rekha Mankad
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s11886-018-1065-9) contains supplementary material, which is available to authorized users.
This article is part of the Topical Collection on Echocardiography

Abstract

Purpose of Review

Cardiac sarcoidosis (CS) is associated with significant morbidity and mortality. The diagnosis of CS is challenging and typically one that is only entertained after many other conditions have been ruled out. A high index of suspicion is necessary in order to correctly determine appropriate testing for the disease. Transthoracic echocardiography is the most readily available imaging modality available to help establish a diagnosis in a potential patient. However, no one echocardiographic feature is pathognomonic.

Recent Findings

On echocardiography, unusual wall motion abnormalities, which do not fit a classic coronary distribution, along with diastolic dysfunction may alert one to the presence of cardiac sarcoid, particularly in the right clinical context. Myocardial strain imaging on echocardiography may increase the sensitivity of identifying cardiac sarcoidosis. Alternative imaging with cardiac magnetic resonance imaging or positron emission tomography have become more frequently utilized to establish a diagnosis of CS.

Summary

Cardiac sarcoidosis remains a difficult condition to diagnose. However early diagnosis is critical to decrease the associated high mortality. Endomyocardial biopsy is highly specific but lacks sensitivity due to the patchy nature of the granulomatous deposition. Thus, imaging plays a role in diagnosis as well as for follow-up. Echocardiography remains an hallmark during the workup for CS. Decreased sensitivity of echocardiography has facilitated the use of other techniques to establish the presence of CS.

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Zusatzmaterial
Video 1 (MP4 873 kb)
11886_2018_1065_MOESM1_ESM.mp4
Video 2 (MP4 714 kb)
11886_2018_1065_MOESM2_ESM.mp4
Literatur
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