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Erschienen in: Child's Nervous System 8/2016

11.03.2016 | Case Report

Ectopic recurrence of pediatric craniopharyngiomas after gross total resection: a report of two cases and a review of the literature

verfasst von: Can Du, Cheng-Yuan Feng, Jian Yuan, Xianrui Yuan

Erschienen in: Child's Nervous System | Ausgabe 8/2016

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Abstract

Introduction

Ectopic recurrent craniopharyngioma is rare. We reported two pediatric cases and reviewed the related literature.

Method

We retrospectively studied 177 craniopharyngioma cases treated by the senior author (Yuan X) between years 2003 and 2013. Two ectopic recurrent craniopharyngiomas were identified. One was discovered under the right frontal lobe and the other was found in the fourth ventricle. Both patients underwent a second radical resection without complications. Then we conducted an extensive review of peer-reviewed, English-language literatures in the US National Library of Medicine, focusing on the treatment modalities, recurrent sites, and clinical outcomes.

Results

Sixty ectopic recurrent tumors have been reported so far (including this study). Thirty-three tumors were located in the previous surgical corridors and 27 were disseminated along the cerebrospinal fluid pathway. All recurrent tumors were surgically removed. The gross total resection (GTR) rates were 87 and 63 %, respectively.

Conclusion

The natural course of recurrent ectopic craniopharyngiomas is progressive. GTR is the treatment of choice. Regular follow-ups are strongly recommended to detect any further recurrence.
Literatur
1.
Zurück zum Zitat Barloon TJ, Yuh WT, Sato Y, Sickels WJ (1988) Frontal lobe implantation of craniopharyngioma by repeated needle aspirations. AJNR Am J Neuroradiol 9:406–407PubMed Barloon TJ, Yuh WT, Sato Y, Sickels WJ (1988) Frontal lobe implantation of craniopharyngioma by repeated needle aspirations. AJNR Am J Neuroradiol 9:406–407PubMed
2.
Zurück zum Zitat de Blank PM, Minturn JE (2011) A rare case of ectopic recurrence of a craniopharyngioma diagnosed 17 years after initial presentation. J Pediatr Hematol Oncol 33:392–397CrossRefPubMed de Blank PM, Minturn JE (2011) A rare case of ectopic recurrence of a craniopharyngioma diagnosed 17 years after initial presentation. J Pediatr Hematol Oncol 33:392–397CrossRefPubMed
3.
Zurück zum Zitat Elfving M, Lundgren J, Englund E, Strömblad L, Erfurth E (2011) Ectopic recurrence of a craniopharyngioma in a 15-year-old girl 9 years after surgery and conventional radiotherapy: case report. Childs Nerv Syst 27:845–851CrossRefPubMed Elfving M, Lundgren J, Englund E, Strömblad L, Erfurth E (2011) Ectopic recurrence of a craniopharyngioma in a 15-year-old girl 9 years after surgery and conventional radiotherapy: case report. Childs Nerv Syst 27:845–851CrossRefPubMed
4.
Zurück zum Zitat Freitag SK, Miller NR, Brem H (2001) Recurrent ectopic craniopharyngioma. Br J Neurosurg 15:511–513CrossRefPubMed Freitag SK, Miller NR, Brem H (2001) Recurrent ectopic craniopharyngioma. Br J Neurosurg 15:511–513CrossRefPubMed
5.
Zurück zum Zitat Gokalp HZ, Egemen N, Ildan F, Bacaci K (1991) Craniopharyngioma of the posterior fossa. Neurosurgery 29:446–448CrossRefPubMed Gokalp HZ, Egemen N, Ildan F, Bacaci K (1991) Craniopharyngioma of the posterior fossa. Neurosurgery 29:446–448CrossRefPubMed
6.
Zurück zum Zitat Israel ZH, Pomeranz S (1995) Intracranial craniopharyngioma seeding following radical resection. Pediatr Neurosurg 22:210–213CrossRefPubMed Israel ZH, Pomeranz S (1995) Intracranial craniopharyngioma seeding following radical resection. Pediatr Neurosurg 22:210–213CrossRefPubMed
7.
Zurück zum Zitat Jakobs M, Orakcioglu B (2012) Ectopic recurrent craniopharyngioma of the frontal bone. J Neurosurg 117:490–497CrossRefPubMed Jakobs M, Orakcioglu B (2012) Ectopic recurrent craniopharyngioma of the frontal bone. J Neurosurg 117:490–497CrossRefPubMed
8.
Zurück zum Zitat Novegno F, Di Rocco F, Colosimo JC, Lauriola L, Caldarelli M (2002) Ectopic recurrences of craniopharyngioma. Childs Nerv Syst 18:468–473CrossRefPubMed Novegno F, Di Rocco F, Colosimo JC, Lauriola L, Caldarelli M (2002) Ectopic recurrences of craniopharyngioma. Childs Nerv Syst 18:468–473CrossRefPubMed
9.
Zurück zum Zitat Ragoowansi AT, Piepgras DG (1991) Postoperative ectopic craniopharyngioma.Case report. J Neurosurg 74:653–655CrossRefPubMed Ragoowansi AT, Piepgras DG (1991) Postoperative ectopic craniopharyngioma.Case report. J Neurosurg 74:653–655CrossRefPubMed
10.
Zurück zum Zitat Elmaci L, Kurtkaya-Yapicier O, Ekinci G, Sav A, Pamir MN, Vidal S, Kovacs K, Scheithauer BW (2002) Metastatic papillary craniopharyngioma: case study and study of tumor angiogenesis. Neuro-Oncology 4:123–128PubMedPubMedCentral Elmaci L, Kurtkaya-Yapicier O, Ekinci G, Sav A, Pamir MN, Vidal S, Kovacs K, Scheithauer BW (2002) Metastatic papillary craniopharyngioma: case study and study of tumor angiogenesis. Neuro-Oncology 4:123–128PubMedPubMedCentral
11.
Zurück zum Zitat Keohane C, Hally M, Ryder DQ, Buckley TF (1994) Late recurrence of craniopharyngioma in the cerebellopontine angle in a fertile woman. J Neurol Neurosurg Psychiatry 57:873–874CrossRefPubMedPubMedCentral Keohane C, Hally M, Ryder DQ, Buckley TF (1994) Late recurrence of craniopharyngioma in the cerebellopontine angle in a fertile woman. J Neurol Neurosurg Psychiatry 57:873–874CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Lee DK, Jung HW, Kim DG, Paek SH, Gwak HS, Choe G (2001) Postoperative spinal seeding of craniopharyngioma. Case report. J Neurosurg 94:617–620CrossRefPubMed Lee DK, Jung HW, Kim DG, Paek SH, Gwak HS, Choe G (2001) Postoperative spinal seeding of craniopharyngioma. Case report. J Neurosurg 94:617–620CrossRefPubMed
13.
Zurück zum Zitat Malik JM, Cosgrove GR, VandenBerg SR (1992) Remote recurrence of craniopharyngioma in the epidural space. Case report. J Neurosurg 77:804–807CrossRefPubMed Malik JM, Cosgrove GR, VandenBerg SR (1992) Remote recurrence of craniopharyngioma in the epidural space. Case report. J Neurosurg 77:804–807CrossRefPubMed
14.
Zurück zum Zitat Elliott RE, Moshel YA, Wisoff JH (2009) Surgical treatment of ectopic recurrence of craniopharyngioma. Report of 4 cases. J Neurosurg Pediatr 4:105–112CrossRefPubMed Elliott RE, Moshel YA, Wisoff JH (2009) Surgical treatment of ectopic recurrence of craniopharyngioma. Report of 4 cases. J Neurosurg Pediatr 4:105–112CrossRefPubMed
15.
Zurück zum Zitat Romani R, Niemela M, Celik O, Isarakul P, Paetau A, Hernesniemi J (2010) Ectopic recurrence of craniopharyngioma along the surgical route: case report and literature review. Acta Neurochir 152:297–302 302CrossRefPubMed Romani R, Niemela M, Celik O, Isarakul P, Paetau A, Hernesniemi J (2010) Ectopic recurrence of craniopharyngioma along the surgical route: case report and literature review. Acta Neurochir 152:297–302 302CrossRefPubMed
16.
Zurück zum Zitat Tomita S, Mendoza ND, Symon L (1992) Recurrent craniopharyngioma in the posterior fossa. Br J Neurosurg 6:587–590CrossRefPubMed Tomita S, Mendoza ND, Symon L (1992) Recurrent craniopharyngioma in the posterior fossa. Br J Neurosurg 6:587–590CrossRefPubMed
17.
Zurück zum Zitat Frangou EM, Tynan JR, Robinson CA, Ogieglo LM, Vitali AM (2009) Metastatic craniopharyngioma: case report and literature review. Childs Nerv Syst 25:1143–1147CrossRefPubMed Frangou EM, Tynan JR, Robinson CA, Ogieglo LM, Vitali AM (2009) Metastatic craniopharyngioma: case report and literature review. Childs Nerv Syst 25:1143–1147CrossRefPubMed
18.
Zurück zum Zitat Fuentes S, Metellus P, Dufour H, Do L, Grisoli F (2002) Postoperative intracranial seeding of craniopharyngioma. Three case reports and a review of the literature. Neurochirurgie 48:345–350PubMed Fuentes S, Metellus P, Dufour H, Do L, Grisoli F (2002) Postoperative intracranial seeding of craniopharyngioma. Three case reports and a review of the literature. Neurochirurgie 48:345–350PubMed
19.
Zurück zum Zitat Goncalves CB, Lima GA, Nogueira J, Do SA, Chimelli L, Taboada GF (2014) Subgaleal recurrence of craniopharyngioma of rapid growing pattern. Pituitary 17:214–219CrossRefPubMed Goncalves CB, Lima GA, Nogueira J, Do SA, Chimelli L, Taboada GF (2014) Subgaleal recurrence of craniopharyngioma of rapid growing pattern. Pituitary 17:214–219CrossRefPubMed
20.
Zurück zum Zitat Gupta K, Kuhn MJ, Shevlin DW, Wacaser LE (1999) Metastatic craniopharyngioma. AJNR Am J Neuroradiol 20:1059–1060PubMed Gupta K, Kuhn MJ, Shevlin DW, Wacaser LE (1999) Metastatic craniopharyngioma. AJNR Am J Neuroradiol 20:1059–1060PubMed
21.
Zurück zum Zitat Ishii K, Sugita K, Kobayashi H, Kamida T, Fujiki M, Izumi T, Mori T (2004) Intracranial ectopic recurrence of craniopharyngioma after Ommaya reservoir implantation. Pediatr Neurosurg 40:230–233CrossRefPubMed Ishii K, Sugita K, Kobayashi H, Kamida T, Fujiki M, Izumi T, Mori T (2004) Intracranial ectopic recurrence of craniopharyngioma after Ommaya reservoir implantation. Pediatr Neurosurg 40:230–233CrossRefPubMed
22.
Zurück zum Zitat Ito M, Jamshidi J, Yamanaka K (2001) Does craniopharyngioma metastasize? Case report and review of the literature. Neurosurgery 48(933–935):935–936 Ito M, Jamshidi J, Yamanaka K (2001) Does craniopharyngioma metastasize? Case report and review of the literature. Neurosurgery 48(933–935):935–936
23.
Zurück zum Zitat Jeong IH, Lee JK, Moon KS, Joo SP, Kwak HJ, Kim TS, Kim JH, Kim SH (2006) Ectopic recurrence of craniopharyngioma: a case report and review of the literature. J Neuro-Oncol 79:191–195CrossRef Jeong IH, Lee JK, Moon KS, Joo SP, Kwak HJ, Kim TS, Kim JH, Kim SH (2006) Ectopic recurrence of craniopharyngioma: a case report and review of the literature. J Neuro-Oncol 79:191–195CrossRef
24.
Zurück zum Zitat Clark SW, Kenning TJ, Evans JJ (2015) Recurrent ectopic craniopharyngioma in the sylvian fissure thirty years after resection through a pterional approach: a case report and review of the literature. Nagoya J Med Sci 77:297–306PubMedPubMedCentral Clark SW, Kenning TJ, Evans JJ (2015) Recurrent ectopic craniopharyngioma in the sylvian fissure thirty years after resection through a pterional approach: a case report and review of the literature. Nagoya J Med Sci 77:297–306PubMedPubMedCentral
25.
Zurück zum Zitat Kawaguchi T, Fujimura M, Shirane R, Shoji T, Watanabe M, Tominaga T (2005) Ectopic recurrence of craniopharyngioma. J Clin Neurosci 12:307–309CrossRefPubMed Kawaguchi T, Fujimura M, Shirane R, Shoji T, Watanabe M, Tominaga T (2005) Ectopic recurrence of craniopharyngioma. J Clin Neurosci 12:307–309CrossRefPubMed
26.
Zurück zum Zitat Kim SK, Wang KC, Shin SH, Choe G, Chi JG, Cho BK (2001) Radical excision of pediatric craniopharyngioma: recurrence pattern and prognostic factors. Childs Nerv Syst 17(531–536):537 Kim SK, Wang KC, Shin SH, Choe G, Chi JG, Cho BK (2001) Radical excision of pediatric craniopharyngioma: recurrence pattern and prognostic factors. Childs Nerv Syst 17(531–536):537
27.
Zurück zum Zitat Lee JH, Kim CY, Kim DG, Jung HW (1999) Postoperative ectopic seeding of craniopharyngioma. Case illustration. J Neurosurg 90:796CrossRefPubMed Lee JH, Kim CY, Kim DG, Jung HW (1999) Postoperative ectopic seeding of craniopharyngioma. Case illustration. J Neurosurg 90:796CrossRefPubMed
28.
Zurück zum Zitat Lermen O, Frank S, Hassler W (2010) Postoperative spinal recurrence of craniopharyngioma. Acta Neurochir 152:309–311, 311CrossRefPubMed Lermen O, Frank S, Hassler W (2010) Postoperative spinal recurrence of craniopharyngioma. Acta Neurochir 152:309–311, 311CrossRefPubMed
29.
Zurück zum Zitat Liu JM, Garonzik IM, Eberhart CG, Sampath P, Brem H (2002) Ectopic recurrence of craniopharyngioma after an interhemispheric transcallosal approach: case report. Neurosurgery 50(639–644):644–645 Liu JM, Garonzik IM, Eberhart CG, Sampath P, Brem H (2002) Ectopic recurrence of craniopharyngioma after an interhemispheric transcallosal approach: case report. Neurosurgery 50(639–644):644–645
30.
Zurück zum Zitat Nomura H, Kurimoto M, Nagai S, Hayashi N, Hirashima Y, Tsukamoto E, Endo S (2002) Multiple intracranial seeding of craniopharyngioma after repeated surgery—case report. Neurol Med Chir (Tokyo) 42:268–271CrossRef Nomura H, Kurimoto M, Nagai S, Hayashi N, Hirashima Y, Tsukamoto E, Endo S (2002) Multiple intracranial seeding of craniopharyngioma after repeated surgery—case report. Neurol Med Chir (Tokyo) 42:268–271CrossRef
31.
Zurück zum Zitat Novak Z, Chrastina J, Feitova V, Lzicarova E, Riha I (2008) Minimally invasive treatment of posterior fossa craniopharyngioma by means of navigated endoscopy. Minim Invasive Neurosurg 51:165–168CrossRefPubMed Novak Z, Chrastina J, Feitova V, Lzicarova E, Riha I (2008) Minimally invasive treatment of posterior fossa craniopharyngioma by means of navigated endoscopy. Minim Invasive Neurosurg 51:165–168CrossRefPubMed
32.
Zurück zum Zitat Salunke P, Bhardwaj LK, Gupta K, Das K (2011) Ectopic recurrence of craniopharyngioma along the surgical tract. Neurol India 59:137–139CrossRefPubMed Salunke P, Bhardwaj LK, Gupta K, Das K (2011) Ectopic recurrence of craniopharyngioma along the surgical tract. Neurol India 59:137–139CrossRefPubMed
33.
Zurück zum Zitat Elliott RE, Hsieh K, Hochm T, Belitskaya-Levy I, Wisoff J, Wisoff JH (2010) Efficacy and safety of radical resection of primary and recurrent craniopharyngiomas in 86 children. J Neurosurg Pediatr 5:30–48CrossRefPubMed Elliott RE, Hsieh K, Hochm T, Belitskaya-Levy I, Wisoff J, Wisoff JH (2010) Efficacy and safety of radical resection of primary and recurrent craniopharyngiomas in 86 children. J Neurosurg Pediatr 5:30–48CrossRefPubMed
34.
Zurück zum Zitat Schmalisch K, Beschorner R, Psaras T, Honegger J (2010) Postoperative intracranial seeding of craniopharyngiomas–report of three cases and review of the literature. Acta Neurochir 152:313–319 319CrossRefPubMed Schmalisch K, Beschorner R, Psaras T, Honegger J (2010) Postoperative intracranial seeding of craniopharyngiomas–report of three cases and review of the literature. Acta Neurochir 152:313–319 319CrossRefPubMed
35.
Zurück zum Zitat Steno J, Bizik I, Steno A, Matejcik V (2011) Craniopharyngiomas in children: how radical should the surgeon be? Childs Nerv Syst 27:41–54CrossRefPubMed Steno J, Bizik I, Steno A, Matejcik V (2011) Craniopharyngiomas in children: how radical should the surgeon be? Childs Nerv Syst 27:41–54CrossRefPubMed
36.
Zurück zum Zitat Tomita T, McLone DG (1993) Radical resections of childhood craniopharyngiomas. Pediatr Neurosurg 19:6–14CrossRefPubMed Tomita T, McLone DG (1993) Radical resections of childhood craniopharyngiomas. Pediatr Neurosurg 19:6–14CrossRefPubMed
37.
Zurück zum Zitat Wang XY, Xu SJ, Li XG (2010) Post-operative implantation metastasis of craniopharyngioma: a case report. J Int Med Res 38:1876–1882CrossRefPubMed Wang XY, Xu SJ, Li XG (2010) Post-operative implantation metastasis of craniopharyngioma: a case report. J Int Med Res 38:1876–1882CrossRefPubMed
38.
Zurück zum Zitat Yamada Y, Haraoka J, Akimoto J (2006) Ectopic recurrence of craniopharyngioma. Neurol Med Chir (Tokyo) 46:598–600CrossRef Yamada Y, Haraoka J, Akimoto J (2006) Ectopic recurrence of craniopharyngioma. Neurol Med Chir (Tokyo) 46:598–600CrossRef
39.
Zurück zum Zitat Yang Y, Shrestha D, Shi XE, Zhou Z, Qi X, Qian H (2015) Ectopic recurrence of craniopharyngioma: reporting three new cases. Br J Neurosurg 29:295–297CrossRefPubMed Yang Y, Shrestha D, Shi XE, Zhou Z, Qi X, Qian H (2015) Ectopic recurrence of craniopharyngioma: reporting three new cases. Br J Neurosurg 29:295–297CrossRefPubMed
40.
Zurück zum Zitat Bikmaz K, Guerrero CA, Dammers R, Krisht AF, Husain MM (2009) Ectopic recurrence of craniopharyngiomas: case report. Neurosurgery 64:E382–E383 E383CrossRefPubMed Bikmaz K, Guerrero CA, Dammers R, Krisht AF, Husain MM (2009) Ectopic recurrence of craniopharyngiomas: case report. Neurosurgery 64:E382–E383 E383CrossRefPubMed
41.
Zurück zum Zitat Bianco AM, Madeira LV, Rosemberg S, Shibata MK (2006) Cortical seeding of a craniopharyngioma after craniotomy: case report. Surg Neurol 66:437–440 440CrossRef Bianco AM, Madeira LV, Rosemberg S, Shibata MK (2006) Cortical seeding of a craniopharyngioma after craniotomy: case report. Surg Neurol 66:437–440 440CrossRef
42.
Zurück zum Zitat Baba M, Iwayama S, Jimbo M, Kitamura K (1978) Cystic craniopharyngioma extending down into the upper cervical spinal canal (author’s transl). No Shinkei Geka 6:687–693PubMed Baba M, Iwayama S, Jimbo M, Kitamura K (1978) Cystic craniopharyngioma extending down into the upper cervical spinal canal (author’s transl). No Shinkei Geka 6:687–693PubMed
Metadaten
Titel
Ectopic recurrence of pediatric craniopharyngiomas after gross total resection: a report of two cases and a review of the literature
verfasst von
Can Du
Cheng-Yuan Feng
Jian Yuan
Xianrui Yuan
Publikationsdatum
11.03.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Child's Nervous System / Ausgabe 8/2016
Print ISSN: 0256-7040
Elektronische ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-016-3050-1

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