Polyetheretherketone (PEEK) is an established implantable orthopaedic biomaterial used spinal surgery, mainly in the form of intervertebral cages. In recent years, there has been a growing interest in improving the affinity of PEEK for bone ongrowth and ingrowth applications. In addition, there has been interest in exploring the potential suitability of PEEK as an orthopaedic-bearing material. Early studies with PEEK bearings examined the possibility of replacing ultra-high molecular weight polyethylene (UHMWPE), but the long-term clinical success of highly crosslinked UHMWPE (HXLPE) diminished practical interest in such applications. Orthopaedic bearings incorporating contemporary ceramic and HXLPE biomaterials are no longer perceived to be clinically limited by their wear characteristics; in large measure for that reason, advances in implant technology must necessarily consider overall economic value alongside clinical efficacy. Because of this new focus, orthopaedists view PEEK biomaterials principally as a potential replacement for metal components, such as the femoral component in total knee replacement. Orthopaedists also view PEEK biomaterials as a potential replacement for metal fracture fixation systems, such as in proximal humerus and distal radius plates and tibial nails.
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