Effect of da Vinci robot versus thoracoscopic surgery on lung function and oxidative stress levels in NSCLC patients: a propensity score-matched study
- 29.11.2023
Erschienen in:
- Verfasst von
- Ziqiang Hong
- Qing Liu
- Hongchao Li
- Baiqiang Cui
- Tao Cheng
- Yingjie Lu
- Xusheng Wu
- Dacheng Jin
- Yunjiu Gou
- Xinchun Dong
- Erschienen in
- Surgical Endoscopy | Ausgabe 2/2024
Abstract
Background
To evaluate the short-term efficacy, lung function, and oxidative stress levels between the robotic-assisted thoracoscopic surgery (RATS) and video-assisted thoracoscopic surgery group (VATS) for non-small cell lung cancer (NSCLC).
Methods
We conducted a retrospective cohort study, selecting 248 NSCLC patients who underwent minimally invasive lobectomy at the Department of Thoracic Surgery, Gansu Provincial People’s Hospital, from August 2019 to February 2023. There were 105 patients in the RATS group and 143 patients in the VATS group. The patients in the two groups were subjected to 1:1 propensity score matching analysis (PSM), and the perioperative indicators were recorded. The levels of oxidative stress factors (superoxide dismutase, SOD; malondialdehyde, MDA) and inflammatory factors were measured 1 day before surgery and 3 days after surgery, respectively. Pulmonary function and patient quality of life were measured at 1 day preoperatively and 3 months postoperatively.
Results
There are 93 patients in each group after PSM. Compared to the VATS group, the RATS group had shorter operation time, less intraoperative blood loss, greater number and groups of lymph nodes cleared, and shorter postoperative hospital stay. The SOD level in the RATS group was higher and the MDA level was lower than that in the VATS group after surgery. Postoperative inflammatory cytokine levels were less elevated in the RATS group than in the VATS group. At 3 months postoperatively, FVC%, FEV1%, and GQOLI-74 scores were higher in the RATS group than in the VATS group.
Conclusion
Compared to VATS lobectomy, RATS lobectomy has the advantages of shorter operative time, lesser bleeding, more lymph node dissection, faster postoperative recovery, and lesser impact on postoperative lung function. It is also capable of reducing the postoperative oxidative stress and inflammatory response, which can improve patients’ quality of life.
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- Titel
- Effect of da Vinci robot versus thoracoscopic surgery on lung function and oxidative stress levels in NSCLC patients: a propensity score-matched study
- Verfasst von
-
Ziqiang Hong
Qing Liu
Hongchao Li
Baiqiang Cui
Tao Cheng
Yingjie Lu
Xusheng Wu
Dacheng Jin
Yunjiu Gou
Xinchun Dong
- Publikationsdatum
- 29.11.2023
- Verlag
- Springer US
- Erschienen in
-
Surgical Endoscopy / Ausgabe 2/2024
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218 - DOI
- https://doi.org/10.1007/s00464-023-10577-x
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