Skip to main content
main-content

09.01.2019 | Original Contributions

Effect of the EndoBarrier Device: a 4-Year Follow-up of a Multicenter Randomized Clinical Trial

Zeitschrift:
Obesity Surgery
Autoren:
Selwyn van Rijn, Yvonne G. M. Roebroek, Charlotte de Jonge, Jan Willem M. Greve, Nicole D. Bouvy
Wichtige Hinweise
Selwyn van Rijn and Yvonne G. M. Roebroek contributed equally to this work.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Objective

To evaluate the long-term effect of the duodenal-jejunal bypass liner (DJBL) on weight loss and glycemic control.

Background

Data on the long-term effect of DJBL treatment is still missing.

Methods

From 2010 to 2012, 29 patients were treated with the DJBL at center A and center B, as part of a multicenter randomized controlled trial. Prior to implantation and after removal of the DJBL, all patients underwent standardized physical examination and blood sampling. Four years after removal of the DJBL, included patients underwent standardized physical examination and blood sampling as previously performed during the initial study.

Results

Out of the 29 patients, 15 patients were eligible for follow-up with a median duration of 42 months. Five patients had successfully received additional bariatric surgery. Four years after explantation of the DJBL, median weight in these 15 patients was 102.0 kg (IQR 94.0–124.6), which was not statistically significantly different from the 106.1 kg at baseline (IQR 99.0–128.4). Median BMI changed from 33.1 kg/m2 (IQR 32.3–38.5) at baseline to 33.7 kg/m2 (IQR 31.2–36.9) after follow-up. Patients had a TWL of 2.2% (IQR − 1.3–5.6) compared to baseline weight. None of the parameters were significantly different after follow-up compared to baseline.

Conclusions

The effect of weight reduction of initial DJBL treatment seems to be diminished after 4 years of follow-up. However, larger prospective studies with long-term follow-up need to be conducted in the future.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Weitere Produktempfehlungen anzeigen
Literatur
Über diesen Artikel
  1. Das kostenlose Testabonnement läuft nach 14 Tagen automatisch und formlos aus. Dieses Abonnement kann nur einmal getestet werden.

Neu im Fachgebiet Chirurgie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Chirurgie und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise