Background
Methods
Criteria for considering studies for this review
Types of participants
Types of interventions and comparators
Outcomes
Types of studies
Literature search
Data collection
Study selection
Data extraction
Quality assessment
Data analysis
Results
Study selection
Characteristics of included studies
Reference in chronological order | General characteristics | Targeted units | Component of scaling-up strategya
| Outcomes | Outcomes | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Country economic status | Funding source | Clinical area | Study design | Setting | Evidence-based practice | C1
| C2
| C3
| C4
| C5
| Scaling-up processb
| Health system | Provider | Patient | ||
Frieden et al. [51] | MIC | Governmental organization | Tuberculosis | Non-RCT | State and district health tuberculosis units | Treatment, short-course (DOTS) strategy for tuberculosis control | Region, patient | ⊠ | Coverage | Sputum smear conversion, cure rate; treatment success | ||||||
Price et al. [52] | LIC | Governmental organization | HIV | Before-after | Primary health centers | Basic HIV care | Site | ⊠ | Reproductive health, services for children, curative services | |||||||
Mutevedzi et al. [53] | MIC | Governmental organization | HIV | Before-after | Primary health care clinics | HIV treatment and care program | Site, patient | ⊠ | Retention in care, mortality, loss to follow-up and virological outcomes | |||||||
Renju et al. [54] | LIC | Governmental organization | Sexually transmitted infection and reproductive health | Before-after | Health units (hospitals, health centers and dispensaries) | Youth-friendly services (YES) intervention | Site, provider | ⊠ | Knowledge and attitudes of health workers | |||||||
Curry et al. [55] | LIC | Voluntary/charitable body | Child care | Before-after | Primary health care units | Some items of Millennium Rural Initiative (EMRI) | Site | ⊠ | ⊠ | Cost-benefit ratio of the EMRI program | Health centre infrastructure and performance | Maternal and child survival | ||||
Goetz et al. [56] | HIC | Research funding body | HIV | Non-RCT | Veterans' healthcare administration facilities | A multimodal program to promote HIV testing | Site | ⊠ | ⊠ | Semi-annual patient load per facility, number of patient visits per year, prevalence of HIV, complexity level | Number of providers seeing the patients during the 6 months of routine testing | HIV testing | ||||
Li et al. [57] | HIC | Governmental organization | Preventing seniors' falls | Before-after | Local senior and community centers | Tai Ji Quan: Moving for Better Balance | Provider | ⊠ | Coverage; measures of program implementation, maintenance and effectiveness | Body mass index, incidence of falls, fear of falling, health status, number of chronic medical conditions | ||||||
Miyano et al. [58] | MIC | Not found | Tuberculosis | CBA | Hospitals and rural health centers | Antiretroviral therapy (ART) services program | Site | ⊠ | ⊠ | HIV testing, tuberculosis treatment outcomes (success, died/failed) | ||||||
Comfort et al. [59] | MIC | Governmental organization | Malaria | Before-after | Hospitals: rural health centers and primary health centers | Malaria control interventions | Site, patient | ⊠ | ⊠ | Costs incurred for malaria admissions | Hospital admissions, outpatient visits for malaria | |||||
Legesse et al. [60] | LIC | Governmental organization | Child care | Non-RCT | Primary health care units | Integrated community case management (iCCM) program | Region, site, patient | ⊠ | ⊠ | ⊠ | Key indicators of iCCM implementation strength, quality of care, utilization of iCCM services, service | Syndromes treated (malaria, suspected pneumonia, diarrhea, severe acute malnutrition) | ||||
Solberg et al. [61] | HIC | Not found | Depression | RCT | Primary care clinics | The IMPACT (Improving Mood: Promoting Access to Collaborative Treatment) model | Site, patient | ⊠ | ⊠ | ⊠ | Depression remission rates, satisfaction with care, work productivity, health status | |||||
Sim et al. [62] | MIC | Voluntary/charitable body | HIV | Before-after | Public health facilities | Linked Response (LR) model | Region, site | Coverage | Pregnant women's access to HIV testing and treatment | |||||||
Munos et al. [63] | LIC | Governmental organization | Child care | Non-RCT | Health districts | iCCM for diarrhea, malaria and pneumonia | Region | ⊠ | ⊠ | ⊠ | ⊠ | Program targets of mortality and coverage, intensity and quality of program implementation, careseeking. | ||||
Singh et al. [64] | MIC | Voluntary/charitable body | Child care | Before-after | Health facilities (health posts, health centers, and hospitals) | Project Fives Alive! | Site | ⊠ | ⊠ | Early antenatal care, skilled delivery coverage, underweight infants at child welfare clinics, under-fives |
Participants
Interventions
Outcomes
Reference in chronological order | Numerator (n) | Denominator (d) | Coverage (n/d) (%) | Timeframe of the scaling-up process | Reported successful coverage | Reported impact on main health outcomes | Used framework | Used framework | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Regions | Sites | Providers | Patients | Regions | Sites | Providers | Patients | Regions | Sites | Providers | Patients | Months | + | – | Unclear | + | – | Unclear | Name | No | |
Frieden et al. [51] | 10,000,000 | 74 | 30 | ⊠ | ⊠g
| ⊠ | |||||||||||||||
Price et al. [52] | 30 | 6 | ⊠ | ⊠g
| ⊠ | ||||||||||||||||
Mutevedzi et al. [53] | 5719 | 16 | 48 | ⊠ | ⊠g
| ⊠ | |||||||||||||||
Renju et al. [54] | 429 | 4 | 177 | 39 | ⊠ | ⊠g
| ⊠ | ||||||||||||||
Curry et al. [55] | 30 |
e
| 18 | ⊠ | ⊠ | ⊠ | |||||||||||||||
Goetz et al. [56] | 15c
| 12 | ⊠ | ⊠g
| ⊠ | ||||||||||||||||
Li et al. [57] | 157 | 63 | 323 | 49 | 22 | ⊠ | ⊠ | RE-AIM | |||||||||||||
Miyano et al. [58] | 8 | ≤ 36 | ⊠ | ⊠g
| ⊠ | ||||||||||||||||
Comfort et al. [59] | 49d
| 400,335d
| ≤ 72 | ⊠ | ⊠ | ⊠ | |||||||||||||||
Legesse et al. [60] | 13,500 |
a
| 4 | 70,000,000 | 31 | ⊠ | ⊠ | ⊠ | |||||||||||||
Solberg et al. [61] | 2348 | 75 | 63 | ⊠ | ⊠g
| ⊠ | |||||||||||||||
Sim et al. [62] | 74 | 956 | 77 | 1004 | 96 | 95 | 57 | ⊠g
| ⊠ | ⊠ | |||||||||||
Munos et al. [63] | 9 |
f
| 35 | ⊠ | ⊠g
| ⊠ | |||||||||||||||
Singh et al. [64] |
b
| 744 | 43 | ⊠ | ⊠g
| ⊠ |