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08.11.2020 | Review

Effectiveness of anesthetic solutions for pain control in lower third molar extraction surgeries: a systematic review of randomized clinical trials with network meta-analysis

verfasst von: Marco Tulio Rossi, Murilo Navarro de Oliveira, Maria Tereza Campos Vidigal, Walbert de Andrade Vieira, Cristiano Elias Figueiredo, Cauane Blumenberg, Vinicius Lima de Almeida, Luiz Renato Paranhos, Luciana Butini Oliveira, Walter Luiz Siqueira, Rui Barbosa de Brito Júnior

Erschienen in: Clinical Oral Investigations | Ausgabe 1/2021

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Abstract

Objective

To assess the effectiveness of different anesthetic solutions for pain control immediately after the extraction of lower third molars.

Methods

Nine databases were used to identify randomized clinical trials, without restriction of language or year of publication. The “JBI Critical Appraisal Tools for Systematic Reviews” was used to assess the risk of bias in the studies. The network meta-analysis was performed to compare the effectiveness of different anesthetics to control the pain immediately after the surgery of lower third molars, using the standardized mean difference (SMD) as the effect estimate. The GRADE approach was used to assess the certainty of evidence.

Results

The search presented 13,739 initial results, from which 45 met the eligibility criteria and presented low to moderate risk of bias. Thirteen studies were included in the meta-analysis. The 2% lidocaine + clonidine presented the lowest pain scores (SMD = − 1.44; − 2.72 to − 0.16) compared to 4% articaine + adrenaline, followed by 0.5% bupivacaine + adrenaline (SMD = − 1.36; − 2.13 to − 0.59). The certainty of evidence varied between very low to moderate.

Conclusion

2% lidocaine + clonidine and 0.5% bupivacaine + adrenaline were the anesthetics with the highest probability for pain control immediately after the surgical procedure of removing impacted lower third molars.

Clinical significance

The use of an adequate anesthetic with effective pain control can contribute to a more comfortable postoperative period.

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Titel: Effectiveness of anesthetic solutions for pain control in lower third molar extraction surgeries: a systematic review of randomized clinical trials with network meta-analysis
verfasst von: Marco Tulio Rossi
Murilo Navarro de Oliveira
Maria Tereza Campos Vidigal
Walbert de Andrade Vieira
Cristiano Elias Figueiredo
Cauane Blumenberg
Vinicius Lima de Almeida
Luiz Renato Paranhos
Luciana Butini Oliveira
Walter Luiz Siqueira
Rui Barbosa de Brito Júnior
Publikationsdatum: 08.11.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 1/2021
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-020-03675-w

Neu im Fachgebiet Zahnmedizin

19.04.2024 | Vorhofflimmern | Nachrichten

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Springer Medizin

Effectiveness of anesthetic solutions for pain control in lower third molar extraction surgeries: a systematic review of randomized clinical trials with network meta-analysis

Abstract

Objective

Methods

Results

Conclusion

Clinical significance

Neu im Fachgebiet Zahnmedizin

Parodontalbehandlung verbessert Prognose bei Katheterablation

Invasive Zahnbehandlung: Wann eine Antibiotikaprophylaxe vor infektiöser Endokarditis schützt

Zell-Organisatoren unter Druck: Mechanismen des embryonalen Zahnwachstums aufgedeckt

Die Oralprophylaxe & Kinderzahnheilkunde umbenannt

Newsletter

Springer Medizin

Abstract

Objective

Methods

Results

Conclusion

Clinical significance

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