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Erschienen in: Lasers in Dental Science 4/2020

15.10.2020 | Original Article

Effectiveness of photobiomodulation in cancer patients with oral mucositis

verfasst von: Fernando Anschau, Jacqueline Webster, Marcelo Eduardo Zanella Capra, Airton Tetelbom Stein

Erschienen in: Lasers in Dental Science | Ausgabe 4/2020

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Abstract

Introduction

Mucositis occurs in more than 40% of chemotherapy-treated patients, significantly reducing their quality of life and increasing interventions for adequate analgesia and nutrition, as well as length of hospital stay. Many different interventions have been evaluated to reduce oral mucositis. Good results have recently been achieved with photobiomodulation (PBM), a technique that has practically no side effects.

Objective

The aim of this study was to evaluate the effectiveness of PBM in the treatment of oral mucositis in patients with leukemia or lymphoma at the Hospital Nossa Senhora da Conceição (HNSC).

Method

Accordingly, an observational retrospective cohort study was conducted with 60 patients with leukemia or lymphoma, comparing time for clinical improvement of oral mucositis in the groups with and without PBM. We included patients of both sexes, 18 years or older, admitted to the HNSC Hematology/Oncology Department from January 2015 to December 2017.

Results

The mean time to resolution of oral mucositis in the PBM-treated group was 7.1 ± 2.57 days and 14.1 ± 6.89 days in the group without PBM (p < 0.001).

Conclusion

PBM was shown to be more effective in reducing oral mucositis compared with the standard treatment protocol alone.
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Metadaten
Titel
Effectiveness of photobiomodulation in cancer patients with oral mucositis
verfasst von
Fernando Anschau
Jacqueline Webster
Marcelo Eduardo Zanella Capra
Airton Tetelbom Stein
Publikationsdatum
15.10.2020
Verlag
Springer International Publishing
Erschienen in
Lasers in Dental Science / Ausgabe 4/2020
Elektronische ISSN: 2367-2587
DOI
https://doi.org/10.1007/s41547-020-00110-x

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