Introduction
Materials and methods
Subjects
Parameter | Unit | Mean ± SD |
---|---|---|
Age | Years | 38.1 ± 6.2 |
Height | cm | 183 ± 7.7 |
Weight | kg | 81.8 ± 8.4 |
Body mass index | kg/m2 | 24.5 ± 2.0 |
Sports activity | min/week | 186 ± 13 |
Heart rate | bpm | 68.1 ± 9.3 |
Systolic blood pressure | mmHg | 126 ± 13.8 |
Diastolic blood pressure | mmHg | 83.1 ± 6.5 |
Study design
Incremental exertion test (IET)
Masks
Measurements
Quantification of comfort/discomfort
Statistical analysis
Results
Pulmonary function
Parameter | Unit | nm | sm | ffpm | ANOVA | nm vs sm | nm vs. ffpm | sm vs ffpm |
---|---|---|---|---|---|---|---|---|
FVC | l | 6.1 ± 1.0 | 5.6 ± 1.0 | 5.3 ± 0.8 | < 0.001 | 0.003 | < 0.001 | 0.032 |
FEV1 | l | 4.3 ± 0.7 | 4.0 ± 0.7 | 3.7 ± 0.6 | 0.001 | 0.001 | 0.003 | 0.068 |
TIFF | % | 70.6 ± 9.7 | 71.2 ± 6.9 | 69.7 ± 4.9 | 0.635 | 0.934 | 0.900 | 0.520 |
PEF | l/s | 9.7 ± 1.6 | 8.7 ± 1.4 | 7.5 ± 1.1 | < 0.001 | 0.026 | 0.001 | 0.040 |
Incremental exertion test
Incremental exertion test | Unit | nm | sm | ffpm | ANOVA | nm vs sm | nm vs. ffpm | sm vs. ffpm |
---|---|---|---|---|---|---|---|---|
Rest | ||||||||
Hemodynamic parameters | ||||||||
HR | bpm | 66.2 ± 9.3 | 66.2 ± 11.8 | 66.2 ± 7.2 | 1.000 | 1.000 | 1.000 | 1.000 |
SV | ml | 100 ± 17.7 | 105 ± 22.3 | 103 ± 21.0 | 0.280 | 0.354 | 0.310 | 0.863 |
CO | l/min | 6.3 ± 0.7 | 6.6 ± 0.7 | 6.6 ± 0.9 | 0.314 | 0.542 | 0.248 | 0.985 |
avDO2 | % | 5.4 ± 1.5 | 4.7 ± 1.3 | 5.1 ± 0.9 | 0.346 | 0.307 | 0.837 | 0.623 |
SBP | mmHg | 117 ± 8.7 | 122 ± 12.3 | 121 ± 12.0 | 0.399 | 0.474 | 0.529 | 0.977 |
DBP | mmHg | 81.9 ± 6.1 | 80.1 ± 6.6 | 81.0 ± 6.2 | 0.569 | 0.494 | 0.836 | 0.907 |
Pulmonary parameters | ||||||||
VE | l/min | 10.5 ± 2.5 | 10.3 ± 2.6 | 10.4 ± 1.9 | 0.822 | 0.898 | 0.967 | 0.958 |
Breathing frequency | brpm | 14.8 ± 2.2 | 12.9 ± 2.9 | 12.5 ± 2.7 | 0.006 | 0.051 | 0.016 | 0.601 |
VT | l | 0.7 ± 0.2 | 0.8 ± 0.2 | 0.9 ± 0.2 | 0.146 | 0.465 | 0.125 | 0.770 |
Metabolic parameters | ||||||||
pH | 7.41 ± 0.02 | 7.44 ± 0.06 | 7.42 ± 0.02 | 0.166 | 0.278 | 0.558 | 0.422 | |
PCO2 | mmHg | 40.2 ± 3.4 | 39.3 ± 3.6 | 39.3 ± 2.2 | 0.094 | 0.179 | 0.213 | 0.998 |
PO2 | mmHg | 111 ± 4.3 | 117 ± 23.1 | 122 ± 22.1 | 0.465 | 0.824 | 0.487 | 0.787 |
Lactate | mmol/l | 1.00 ± 0.27 | 0.78 ± 0.26 | 1.04 ± 0.52 | 0.125 | 0.003 | 0.962 | 0.281 |
Maximum load | ||||||||
Peformance | ||||||||
Pmax | W | 277 ± 45.9 | 269 ± 45.1 | 263 ± 41.7 | 0.002 | 0.071 | 0.005 | 0.018 |
Pmax/kg | W/kg | 3.40 ± 0.5 | 3.30 ± 0.5 | 3.22 ± 0.4 | 0.001 | 0.066 | 0.005 | 0.019 |
VO2max/kg | (ml/min)/kg | 39.7 ± 5.8 | 37.9 ± 6.0 | 34.5 ± 5.3 | < 0.001 | 0.063 | 0.001 | 0.013 |
Hemodynamic parameters | ||||||||
HR | bpm | 187 ± 8.3 | 183 ± 9.2 | 182 ± 11.2 | 0.106 | 0.031 | 0.107 | 0.964 |
SV | ml | 151 ± 26.4 | 165 ± 35.0 | 164 ± 20.4 | 0.086 | 0.166 | 0.074 | 0.979 |
CO | l/min | 25.8 ± 4.2 | 27.3 ± 5.6 | 27.0 ± 3.8 | 0.342 | 0.435 | 0.422 | 0.964 |
avDO2 | % | 12.8 ± 2.8 | 11.5 ± 2.2 | 10.5 ± 2.0 | 0.002 | 0.084 | 0.007 | 0.172 |
SBP | mmHg | 214 ± 18.2 | 212 ± 28.5 | 210 ± 18.8 | 0.901 | 0.984 | 0.905 | 0.954 |
DBP | mmHg | 88.8 ± 9.6 | 95.8 ± 36.7 | 89.8 ± 8.8 | 0.582 | 0.779 | 0.959 | 0.847 |
Pulmonary parameters | ||||||||
VE | l/min | 131 ± 27.8 | 114 ± 23.3 | 98.8 ± 18.6 | 0.001 | 0.048 | 0.003 | 0.009 |
Breathing frequency | brpm | 40.9 ± 5.1 | 39.3 ± 6.2 | 36.8 ± 5.9 | 0.019 | 0.518 | 0.024 | 0.138 |
VT | l | 3.2 ± 0.7 | 2.9 ± 0.5 | 2.7 ± 0.4 | 0.016 | 0.255 | 0.021 | 0.102 |
Metabolic parameters | ||||||||
pH | 7.27 ± 0.05 | 7.32 ± 0.10 | 7.31 ± 0.06 | 0.158 | 0.216 | 0.065 | 0.989 | |
PCO2 | mmHg | 34.2 ± 3.8 | 34.3 ± 5.9 | 34.9 ± .0 | 0.726 | 0.999 | 0.560 | 0.943 |
PO2 | mmHg | 107 ± 20.5 | 116 ± 23.7 | 116 ± 23.2 | 0.502 | 0.714 | 0.339 | 0.996 |
Lactate | mmol/l | 12.8 ± 3.09 | 11.0 ± 3.91 | 10.8 ± 3.12 | 0.049 | 0.132 | 0.105 | 0.985 |
Recovery | ||||||||
Hemodynamic parameters | ||||||||
HRR-1 min | bpm | −39.7 ± 15.9 | −38.1 ± 9.2 | −39.9 ± 11.2 | 0.203 | 0.055 | 0.611 | 0.781 |
HRR-5 min | bpm | −72.5 ± 24.1 | −77.6 ± 11.5 | −77.3 ± 10.9 | 0.874 | 0.938 | 0.855 | 0.991 |
Perceived discomfort
Discomfort | nm | sm | ffpm | ANOVA | nm vs sm | nm vs ffpm | sm vs ffpm |
---|---|---|---|---|---|---|---|
Humid | 2.4 ± 2.0 | 4.9 ± 3.2 | 5.9 ± 2.2 | 0.003 | 0.069 | 0.001 | 0.402 |
Hot | 2.0 ± 1.3 | 4.2 ± 2.4 | 6.2 ± 2.3 | < 0.001 | 0.012 | < 0.001 | 0.024 |
Breath resistance | 1.7 ± 1.2 | 5.4 ± 1.9 | 7.4 ± 2.5 | < 0.001 | 0.001 | < 0.001 | 0.045 |
Itchy | 1.1 ± 1.0 | 3.4 ± 3.1 | 4.9 ± 2.6 | 0.002 | 0.030 | 0.001 | 0.331 |
Tight | 1.9 ± 1.8 | 3.9 ± 2.6 | 6.5 ± 2.3 | < 0.001 | 0.035 | < 0.001 | 0.021 |
Salty | 0.7 ± 1.1 | 1.6 ± 1.5 | 3.5 ± 2.8 | 0.003 | 0.261 | 0.012 | 0.023 |
Unfit | 1.4 ± 1.2 | 3.3 ± 2.3 | 5.4 ± 2.3 | < 0.001 | 0.009 | < 0.001 | 0.016 |
Odor | 1.4 ± 2.2 | 1.2 ± 0.9 | 3.6 ± 2.8 | 0.011 | 0.956 | 0.056 | 0.036 |
Fatigue | 2.7 ± 2.2 | 5.8 ± 2.5 | 6.5 ± 2.6 | < 0.001 | 0.002 | 0.001 | 0.394 |
Overall discomfort | 2.8 ± 2.2 | 5.2 ± 2.1 | 7.0 ± 1.7 | < 0.001 | 0.012 | < 0.001 | 0.005 |