The authors declare that they have no competing interests.
XFH designed the study protocol, collected the data, performed the statistical analysis, and drafted the manuscript. QSH aided to collect the data and draft the manuscript. SC helped to perform the statistical analysis and interpreted the data. JZ and KQL both helped to collect the data. XMZ conceived the study concept, designed the study protocol and co-ordinate the whole research procedure, helped to do data analysis and finalising the manuscript. All authors read and approved the final manuscript.
Adenomyomectomy has recently been considered the priority option for the treatment of adenomyosis, however, the surgical efficacy and modes are still debated. We aimed to evaluate the efficacy of laparoscopic adenomyomectomy using a double-flap method for the treatment of uterine diffuse adenomyosis when compared with conventional laparoscopic adenomyomectomy.
Laparoscopic adenomyomectomy using the conventional method (group A, n = 48) and the double-flap method (group B, n = 46) to treat diffuse uterine adenomyosis, respectively. Visual analog scale (VAS), menstrual amount, serum CA125 levels, and uterine volume were comparatively analyzed in both groups.
The VAS scores, menstrual amount, serum CA125 levels, and uterine volume at 12 or 24 months after surgery significantly reduced in group B than in group A (P < 0.05); these parameters were statistically decreased in both groups after surgery compared with those obtained before surgery (P < 0.001). Moreover, serum CA125 levels and uterine volume at six months of follow up were significantly lower in group B than in group A (P < 0.01). In addition, blood loss during surgery was similar in groups A and B (P > 0.05), although the operative time was significantly longer in group B than that in group A (P < 0.05).
Laparoscopic adenomyomectomy using the double-flap method may be an effective technique to treat uterine diffuse adenomyosis.
Wang CJ, Yuen LT, Chang SD, Lee CL, Soong YK. Use of laparoscopic cytoreductive surgery to treat infertile women with localized adenomyosis. Fertil Steril. 2006;86:462.e5-8. PubMed
Zheng J, Xia E, Li TC, Sun X. Comparison of combined transcervical resection of the endometrium and levonorgestrel-containing intrauterine system treatment versus levonorgestrel-containing intrauterine system treatment alone in women with adenomyosis: a prospective clinical trial. J Reprod Med. 2013;58:285–90. PubMed
Huang BS, Seow KM, Tsui KH, Huang CY, Lu YF, Wang PH. Fertility outcome of infertile women with adenomyosis treated with the combination of a conservative microsurgical technique and GnRH agonist: long-term follow-up in a series of nine patients. Taiwan J Obstet Gynecol. 2012;51:212–6. CrossRefPubMed
Sun AJ, Luo M, Wang W, Chen R, Lang JH. Characteristics and efficacy of modified adenomyomectomy in the treatment of uterine adenomyoma. Chin Med J (Engl). 2011;124:1322–6.
Shrestha A, Sedai LB. Understanding clinical features of adenomyosis: a case control study. Nepal Med Coll J. 2012;14:176–9. PubMed
Sakhel K, Abuhamad A. Sonography of adenomyosis. J Ultrasound Med. 2012;31:805–8. PubMed
Xu H, Yang Y, Zhou C, Huang X, Lin J, Zhang X. Increased endometrial expression of CC-chemokine receptor-1 in women with adenomyosis. Histol Histopathol. 2014;29:1153–60. PubMed
Akira S, Mine K, Kuwabara Y, Takeshita T. Efficacy of long-term, low-dose gonadotropin-releasing hormone agonist therapy (draw-back therapy) for adenomyosis. Med Sci Monit. 2009;15:CR1–4. PubMed
Kwon YS, Roh HJ, Ahn JW, Lee SH, Im KS. Conservative adenomyomectomy with transient occlusion of uterine arteries for diffuse uterine adenomyosis. J Obstet Gynaecol Res. 2014. doi: 10.1111/jog.12649. [Epub ahead of print].
- Efficacy of laparoscopic adenomyomectomy using double-flap method for diffuse uterine adenomyosis
- BioMed Central
Neu im Fachgebiet Gynäkologie und Geburtshilfe
Meistgelesene Bücher aus dem Fachgebiet
e.Med Kampagnen-Visual, Mail Icon II