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Erschienen in: Rheumatology International 6/2012

01.06.2012 | Original Article

Ehlers–Danlos syndrome: case report and an electron microscopy study

verfasst von: M. Carlesimo, G. Cortesi, A. Gamba, A. Narcisi, F. Turturro, S. Raffa, M. R. Torrisi, G. Camplone

Erschienen in: Rheumatology International | Ausgabe 6/2012

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Abstract

Ehlers–Danlos syndrome (EDS) type III is a inherited connective tissue disorders characterized by extensibility of the skin, hypermobility of the joints, chronic pain, tissue fragility, easy bruising, and delayed wound healing with result of atrophic scars. The patients report commonly a history of recurrent dislocations of the shoulders and knees after low-impact trauma, chronic joint pain, and early osteoarthritis, which lead to diagnosis. The pathogenesis of this condition is unknown, and the diagnosis is generally made in adult age, based only on clinical criteria. In this report, we describe a case of a 50-year-old woman with a 30-year history of recurrent dislocations and atrophic scars. We performed diagnosis of EDS type III after a complete clinical and instrumental evaluation, comprising of histological and electron microscopic studies, that highlighted collagen abnormalities.
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Metadaten
Titel
Ehlers–Danlos syndrome: case report and an electron microscopy study
verfasst von
M. Carlesimo
G. Cortesi
A. Gamba
A. Narcisi
F. Turturro
S. Raffa
M. R. Torrisi
G. Camplone
Publikationsdatum
01.06.2012
Verlag
Springer-Verlag
Erschienen in
Rheumatology International / Ausgabe 6/2012
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-010-1778-6

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